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DENND6A [cytosol]
Stable Identifier
R-HSA-8876587
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Protein DENND6A, DEN6A_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
DENND6A,B exchange GTP for GDP on RAB14 (Homo sapiens)
DENND6A,B [cytosol] (Homo sapiens)
DENND6A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IWF6 DENND6A
Gene Names
DENND6A, FAM116A
Chain
chain:1-608
Reference Genes
BioGPS Gene:201627 DENND6A
COSMIC (genes):DENND6A DENND6A
CTD Gene:201627 DENND6A
dbSNP Gene:201627 DENND6A
ENSEMBL:ENSG00000174839 DENND6A
ENSEMBL_homo_sapiens_GENE:ENSG00000174839.13 DENND6A
HGNC:26635 DENND6A
KEGG Gene (Homo sapiens):201627 DENND6A
Monarch:201627 DENND6A
NCBI Gene:201627 DENND6A
OMIM:620561 DENND6A
UCSC:Q8IWF6 DENND6A
Reference Transcript
RefSeq:NM_152678.2 DENND6A
Other Identifiers
11758454_s_at
16955456
201627
226965_PM_at
226965_at
2678117
2678118
2678119
2678120
2678121
2678122
2678126
2678127
2678128
2678132
2678134
2678135
2678138
2678139
2678141
2678142
2678147
2678150
2678151
2678153
2678155
2678156
2678157
2678158
2678163
2678164
2678165
2678166
63303_at
70783_at
8088348
A_32_P118586
GO:0005085
GO:0005737
GO:0005768
GO:0005829
GO:0007155
GO:0031410
GO:0043226
GO:0043231
GO:0055037
GO:0098772
GO:2000049
HMNXSV003015357
HMNXSV003017718
Hs.99670.0.A1_3p_at
ILMN_1713178
PH_hs_0022209
TC03001496.hg
Participates
as a member of
DENND6A,B [cytosol] (Homo sapiens)
Inferred To
BEST:LD39762 [cytosol]
(Drosophila melanogaster)
DENND6A [cytosol]
(Bos taurus)
DENND6A [cytosol]
(Caenorhabditis elegans)
DENND6A [cytosol]
(Dictyostelium discoideum)
DENND6A [cytosol]
(Gallus gallus)
Dennd6a [cytosol]
(Mus musculus)
Dennd6a [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_689891.1
OpenTargets
ENSG00000174839
HPA
ENSG00000174839-DENND6A
GeneCards
Q8IWF6
Ensembl
ENST00000311128
,
ENSG00000174839
,
ENSP00000311401
PRO
Q8IWF6
Pharos - Targets
Q8IWF6
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37173 TGFBR2
9
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 [plasma membrane]
(R-HSA-170842)
0.527
3
UniProt:Q8TDQ0 HAVCR2
1
HAVCR2 [plasma membrane]
(R-HSA-5340408)
0.527
2
UniProt:Q7KYR7 BTN2A1
1
BTN2A1 [plasma membrane]
(R-HSA-8851994)
0.527
2
UniProt:Q15116 PDCD1
2
p-Y223,Y248-PDCD1 [plasma membrane]
(R-HSA-389736)
PDCD1 [plasma membrane]
(R-HSA-197604)
0.527
2
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