ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane

Stable Identifier
R-HSA-8847638
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NSF-mediated ATP hydrolysis promotes disassembly of the cis-SNARE complex, allowing the SNAREs to be reused in subsequent rounds of vesicle fusion (reviewed in Sudhof and Rothman, 2009; Hong and Lev, 2014).

Literature References
PubMed ID Title Journal Year
19164740 Membrane fusion: grappling with SNARE and SM proteins

S├╝dhof, TC, Rothman, JE

Science 2009
24119662 Tethering the assembly of SNARE complexes

Hong, W, Lev, S

Trends Cell Biol. 2014
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ATPase activity of STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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