Reactome | SF3A3 [nucleoplasm]

SF3A3 [nucleoplasm]

Stable Identifier

R-HSA-71966

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SAP 61 (Splicing factor 3A subunit 3), Splicing factor 3A subunit 3, Spliceosome associated protein 61, SAP 61, SF3a60

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q12874 SF3A3

Gene Names

SF3A3, SAP61

Chain

chain:1-501

Reference Genes

BioGPS Gene:10946 SF3A3

COSMIC (genes):SF3A3 SF3A3

CTD Gene:10946 SF3A3

dbSNP Gene:10946 SF3A3

ENSEMBL:ENSG00000183431 SF3A3

HGNC:10767 SF3A3

KEGG Gene (Homo sapiens):10946 SF3A3

Monarch:10946 SF3A3

NCBI Gene:10946 SF3A3

OMIM:605596 SF3A3

UCSC:Q12874 SF3A3

Reference Transcript

RefSeq:NM_006802.3 SF3A3

Other Identifiers

10946

11718112_at

11718113_a_at

16685544

203818_s_at

2407440

2407441

2407442

2407443

2407445

2407447

2407448

2407449

2407450

2407452

2407455

2407456

2407459

2407461

2407462

2407465

2407466

2407468

2407471

3395675

3395676

37379_at

3895496

3895497

3895498

3895504

3895506

3895507

3895508

3895511

4044003

4044004

4044005

4044006

4044008

7915130

A_21_P0000193

A_32_P63913

GE60076

GO:0000375

GO:0000389

GO:0000398

GO:0003674

GO:0003676

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0005686

GO:0006397

GO:0008150

GO:0008270

GO:0008380

GO:0016607

GO:0022607

GO:0022618

GO:0032991

GO:0034641

GO:0043167

GO:0043226

GO:0046872

GO:0065003

GO:0071005

GO:0071013

GO:1903241

HMNXSV003038052

ILMN_1705151

PH_hs_0004499

PH_hs_0040561

TC01002529.hg

U08815_at

g5803166_3p_a_at

Participates

as a component of

SF3A [nucleoplasm] (Homo sapiens)

Inferred To

Sf3a3 [nucleoplasm] (Mus musculus)

Sf3a3 [nucleoplasm] (Rattus norvegicus)

sf3a3 [nucleoplasm] (Danio rerio)

sf3a3 [nucleoplasm] (Xenopus tropicalis)

prp-9 [nucleoplasm] (Caenorhabditis elegans)

SF3A3 [nucleoplasm] (Canis familiaris)

SF3A3 [nucleoplasm] (Dictyostelium discoideum)

SF3A3 [nucleoplasm] (Gallus gallus)

SF3A3 [nucleoplasm] (Sus scrofa)

noi [nucleoplasm] (Drosophila melanogaster)

sap61 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_006793.1

OpenTargets

ENSG00000183431

GeneCards

Q12874

HPA

ENSG00000183431-SF3A3

Ensembl

ENSP00000362110, ENSG00000183431, ENST00000373019

PRO

Q12874

Pharos - Targets

Q12874

GlyGen

Q12874

PDB

6AH0, 6Y53, 6Y5Q, 6Y50, 2DT7, 6AHD, 7ONB, 7ABH, 7ABI, 5Z57, 5Z58, 6QX9, 6FF7, 7ABG, 5Z56

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.508	2