Reactome | PCBP2 [nucleoplasm]

PCBP2 [nucleoplasm]

Stable Identifier

R-HSA-71921

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hnRNP-E2, PCB2_HUMAN, Poly(rC)-binding protein 2, Alpha-CP2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15366 PCBP2

Gene Names

PCBP2

Chain

chain:1-365

Reference Genes

BioGPS Gene:5094 PCBP2

COSMIC (genes):PCBP2 PCBP2

CTD Gene:5094 PCBP2

dbSNP Gene:5094 PCBP2

ENSEMBL:ENSG00000197111 PCBP2

ENSEMBL:ENSG00000197111.16 PCBP2

HGNC:8648 PCBP2

KEGG Gene (Homo sapiens):5094 PCBP2

Monarch:5094 PCBP2

NCBI Gene:5094 PCBP2

OMIM:601210 PCBP2

UCSC:Q15366 PCBP2

Reference Transcript

Other Identifiers

11728665_a_at

11728666_s_at

11728667_x_at

11729213_a_at

11753946_x_at

11754995_a_at

204031_PM_s_at

204031_s_at

213263_PM_s_at

213263_s_at

213264_PM_at

213264_at

3140984

3140985

3140989

3140990

3140991

3416037

3416043

3416044

3416045

3416049

3416050

3416052

3416055

3416056

3416058

3416062

3416064

3416066

3416068

3416070

3416071

3416080

3416081

3416082

3416083

3416084

35745_f_at

35746_r_at

40997_at

5094

78178_at

78180_g_at

7955817

A_23_P204052

A_24_P141688

A_33_P3298492

GE81464

GO:0002376

GO:0003676

GO:0003677

GO:0003697

GO:0003723

GO:0003729

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005925

GO:0006351

GO:0006355

GO:0010468

GO:0014069

GO:0016020

GO:0016071

GO:0019899

GO:0030163

GO:0031625

GO:0039694

GO:0043161

GO:0043226

GO:0045087

GO:0045824

GO:0045944

GO:0050687

GO:0051252

GO:0051607

GO:0070062

GO:0075522

GO:0098542

GO:1990829

GO:1990904

HMNXSV003000464

HMNXSV003049278

Hs.211601.1.S1_3p_at

ILMN_1724825

ILMN_2312296

PH_hs_0029183

TC12003242.hg

X78136_at

g4826885_3p_a_at

Participates

as a component of

hnRNP proteins [nucleoplasm] (Homo sapiens)

as a member of

Alternative Splicing Factors [nucleoplasm] (Homo sapiens)

Other forms of this molecule

PCBP2 [cytosol]

Inferred To

PBP2 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of PCBP2 [nucleoplasm] (Saccharomyces cerevisiae)

Pcbp2 [nucleoplasm] (Mus musculus)

Pcbp2 [nucleoplasm] (Rattus norvegicus)

PCBP2 [nucleoplasm] (Bos taurus)

PCBP2 [nucleoplasm] (Canis familiaris)

PCBP2 [nucleoplasm] (Gallus gallus)

PCBP2 [nucleoplasm] (Sus scrofa)

HEK2 [nucleoplasm] (Saccharomyces cerevisiae)

pes-4 [nucleoplasm] (Caenorhabditis elegans)

PCBP3 [nucleoplasm] (Danio rerio)

pcbp3 [nucleoplasm] (Xenopus tropicalis)

rnc1 [nucleoplasm] (Schizosaccharomyces pombe)

mub [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001092090.1, NP_005007.2, NP_001122384.1, NP_001122386.1, NP_001122383.1, NP_001122385.1, NP_114366.1

OpenTargets

ENSG00000197111

GeneCards

Q15366

HPA

ENSG00000197111-PCBP2

Ensembl

ENSP00000449062, ENST00000546463, ENSP00000390304, ENST00000552296, ENST00000359462, ENSP00000352438, ENSP00000352228, ENSG00000197111, ENST00000447282, ENSP00000449070, ENST00000552819, ENSP00000448762, ENSP00000394116, ENST00000359282, ENST00000548933, ENST00000455667, ENSP00000448927, ENST00000437231, ENSP00000388008, ENSP00000408949, ENST00000439930

PRO

Q15366

Pharos - Targets

Q15366

PDB

2AXY, 2PQU, 2JZX, 2P2R, 2PY9

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P84103 SRSF3	1	SRSF3 [nucleoplasm] (R-HSA-72035)	0.581	3
UniProt:P09012 SNRPA	1	SNRPA [nucleoplasm] (R-HSA-71915)	0.556	3
UniProt:Q12771 Q12771			0.527	2
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.527	2
UniProt:Q15365 PCBP1	1	PCBP1 [nucleoplasm] (R-HSA-71919)	0.508	2
IntAct:EBI-2643306 CEBPA-UORF			0.499	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	12
UniProt:Q8IUH3 RBM45			0.462	2