Reactome | PCBP2 [nucleoplasm]

PCBP2 [nucleoplasm]

Stable Identifier

R-HSA-71921

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hnRNP-E2, PCB2_HUMAN, Poly(rC)-binding protein 2, Alpha-CP2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15366 PCBP2

Gene Names

PCBP2

Chain

chain:1-365

Reference Genes

BioGPS Gene:5094 PCBP2

COSMIC (genes):PCBP2 PCBP2

CTD Gene:5094 PCBP2

dbSNP Gene:5094 PCBP2

ENSEMBL:ENSG00000197111 PCBP2

HGNC:8648 PCBP2

KEGG Gene (Homo sapiens):5094 PCBP2

Monarch:5094 PCBP2

NCBI Gene:5094 PCBP2

OMIM:601210 PCBP2

UCSC:Q15366 PCBP2

Reference Transcript

Other Identifiers

0002260093

11728665_a_at

11728666_s_at

11728667_x_at

11729213_a_at

11753946_x_at

11754995_a_at

204031_s_at

213263_s_at

213264_at

3140984

3140985

3140989

3140990

3140991

3416037

3416043

3416044

3416045

3416049

3416050

3416052

3416055

3416056

3416058

3416062

3416064

3416066

3416068

3416070

3416071

3416080

3416081

3416082

3416083

3416084

35745_f_at

35746_r_at

40997_at

5094

78178_at

78180_g_at

7955817

A_23_P204052

A_24_P141688

A_33_P3298492

GE81464

GO:0000398

GO:0002376

GO:0003674

GO:0003676

GO:0003677

GO:0003723

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005925

GO:0006397

GO:0006950

GO:0008150

GO:0009056

GO:0016020

GO:0016032

GO:0016070

GO:0016071

GO:0019899

GO:0031625

GO:0032480

GO:0034641

GO:0039694

GO:0043161

GO:0043226

GO:0044403

GO:0045087

GO:0050687

GO:0051607

GO:0070062

GO:0075522

GO:1990829

Hs.211601.1.S1_3p_at

ILMN_1724825

ILMN_2312296

ILMN_3249963

ILMN_3251155

PH_hs_0029183

TC12003242.hg

X78136_at

g4826885_3p_a_at

Participant Of

input

Formation of pre-mRNPs

hasComponent

output

Cleavage at the 3'-Splice Site and Exon Ligation

Other forms of this molecule

PCBP2 [cytosol]

Inferred To

Pcbp2 [nucleoplasm] (Mus musculus)

Pcbp2 [nucleoplasm] (Rattus norvegicus)

LOC426023 [nucleoplasm] (Gallus gallus)

PCBP2 [nucleoplasm] (Bos taurus)

PCBP2 [nucleoplasm] (Canis familiaris)

PCBP2 [nucleoplasm] (Dictyostelium discoideum)

PCBP2 [nucleoplasm] (Sus scrofa)

pcbp2 [nucleoplasm] (Danio rerio)

pes-4 [nucleoplasm] (Caenorhabditis elegans)

pcbp3 [nucleoplasm] (Xenopus tropicalis)

mub [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001122385.1, NP_001122386.1, NP_001122383.1, NP_114366.1, NP_005007.2, NP_001122384.1, NP_001092090.1

OpenTargets

ENSG00000197111

GeneCards

Q15366

HPA

ENSG00000197111-PCBP2

Ensembl

ENST00000447282, ENSP00000448927, ENST00000455667, ENSP00000352228, ENST00000552819, ENST00000439930, ENST00000546463, ENST00000359282, ENSP00000394116, ENSP00000448762, ENSP00000449070, ENSP00000390304, ENSG00000197111, ENST00000548933, ENST00000359462, ENSP00000449062, ENSP00000352438, ENSP00000408949, ENSP00000388008, ENST00000552296, ENST00000437231

PRO

Q15366

PDB

2JZX, 2AXY, 2P2R, 2PY9, 2PQU

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P84103 SRSF3	1	SRSF3 [nucleoplasm] (R-HSA-72035)	0.581	3
UniProt:P09012 SNRPA	1	SNRPA [nucleoplasm] (R-HSA-71915)	0.556	3
UniProt:Q12771 Q12771			0.527	2
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.527	2
UniProt:Q15365 PCBP1	1	PCBP1 [nucleoplasm] (R-HSA-71919)	0.508	2
IntAct:EBI-2643306 CEBPA-UORF			0.499	4