Reactome | TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-6814813

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

TBC1 domain family member 20

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96BZ9 TBC1D20

Gene Names

TBC1D20, C20orf140

Chain

chain:1-403

Reference Genes

BioGPS Gene:128637 TBC1D20

COSMIC (genes):TBC1D20 TBC1D20

CTD Gene:128637 TBC1D20

dbSNP Gene:128637 TBC1D20

ENSEMBL:ENSG00000125875 TBC1D20

HGNC:16133 TBC1D20

KEGG:hsa:128637 TBC1D20

Monarch:128637 TBC1D20

NCBI Gene:128637 TBC1D20

OMIM:611663 TBC1D20

UCSC:Q96BZ9 TBC1D20

Reference Transcript

Other Identifiers

11728738_x_at

11728739_a_at

11728740_a_at

128637

16916312

226409_PM_at

226409_at

226664_PM_at

226664_at

3894187

3894193

3894195

3894196

3894197

3894198

3894199

3894200

3894201

3894202

3894203

3894205

3894206

3894207

3894208

3894209

3894210

3894211

3894212

3894213

3894214

3894216

3894217

3894222

3894223

45812_at

58325_at

8064336

A_23_P354187

A_23_P354193

A_24_P392958

GE57020

GE61475

GO:0000139

GO:0001675

GO:0002088

GO:0005096

GO:0005515

GO:0005783

GO:0005789

GO:0006888

GO:0007030

GO:0007283

GO:0008584

GO:0016020

GO:0016192

GO:0019068

GO:0022414

GO:0031267

GO:0031965

GO:0033116

GO:0034389

GO:0043010

GO:0043226

GO:0043547

GO:0044829

GO:0046726

GO:0048856

GO:0070309

GO:0072520

GO:0090110

GO:0098772

GO:1902953

HMNXSV003024000

HMNXSV003057899

Hs.16475.0.S1_3p_at

Hs.167827.0.S1_3p_at

ILMN_1742869

ILMN_1836440

ILMN_2044572

PH_hs_0002559

PH_hs_0023018

TC20000541.hg

Participates

as a component of

as an input of

as an output of

TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Homo sapiens)

Inferred To

Dmel\CG17883 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

tbc-20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

GYP8 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)

tbc1d20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)

TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)

TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Plasmodium falciparum)

Tbc1d20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Tbc1d20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

gyp10 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

XP_005260718.1, NP_653229.1

OpenTargets

ENSG00000125875

ENSEMBL

ENSP00000505500, ENSP00000505557, ENSG00000125875, ENST00000679944, ENST00000680106, ENST00000681636, ENST00000679741, ENSP00000432280, ENST00000681539, ENSP00000504904, ENST00000354200, ENSP00000506122, ENST00000680792, ENST00000681742, ENST00000680284, ENSP00000506012, ENSP00000506278, ENSP00000506155, ENSP00000506231, ENSP00000346139, ENST00000461304

HPA

ENSG00000125875-TBC1D20

GeneCards

TBC1D20

PRO

Q96BZ9

Pharos - Targets

Q96BZ9

Orphanet

TBC1D20

PDB

4HL4, 4HLQ

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27958-PRO_0000037576			0.697	11
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:P55056 APOC4	1	APOC4 [extracellular region] (R-HSA-5215930)	0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3

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