Reactome | APOC4 [extracellular region]

APOC4 [extracellular region]

Stable Identifier

R-HSA-5215930

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Apolipoprotein C-IV, APOC4_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P55056 APOC4

Gene Names

APOC4

Chain

signal peptide:1-27, chain:28-127

Reference Genes

BioGPS Gene:346 APOC4

COSMIC (genes):APOC4 APOC4

CTD Gene:346 APOC4

dbSNP Gene:346 APOC4

ENSEMBL:ENSG00000267467 APOC4

ENSEMBL_homo_sapiens_GENE:ENSG00000267467.4 APOC4

HGNC:611 APOC4

KEGG Gene (Homo sapiens):346 APOC4

Monarch:346 APOC4

NCBI Gene:346 APOC4

OMIM:600745 APOC4

UCSC:P55056 APOC4

Reference Transcript

RefSeq:NM_001646.2 APOC4

Other Identifiers

11734042_at

16863138

206738_PM_at

206738_at

34454_r_at

346

3835913

3835914

3835916

3835917

3835918

3835919

3835920

8029541

A_23_P27450

A_33_P3209162

GE79711

GO:0005215

GO:0005319

GO:0005515

GO:0005576

GO:0005615

GO:0006629

GO:0006869

GO:0010890

GO:0034361

GO:0034364

GO:0070328

HMNXSV003042666

ILMN_1765605

PH_hs_0028567

TC19002643.hg

U32576_rna1_at

g4502160_3p_at

Participates

as an output of

Expression of APOC4 regulated by NR1H2 or NR1H3 (Homo sapiens)

as a component of

VLDL [extracellular region] (Homo sapiens)

as an input of

VLDL binds APOC1 and APOC4 (Homo sapiens)

Inferred To

APOC4 [extracellular region] (Canis familiaris)

Apoc4 [extracellular region] (Mus musculus)

Apoc4 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_001637.1

OpenTargets

ENSG00000267467

HPA

ENSG00000267467-APOC4

GeneCards

P55056

Ensembl

ENSG00000267467, ENST00000592954, ENSP00000468236

PRO

P55056

Pharos - Targets

P55056

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:Q9NPL8 TIMMDC1	1	TIMMDC1 [mitochondrial inner membrane] (R-HSA-5689720)	0.556	3
UniProt:Q6P1Q0 LTMD1			0.556	3
UniProt:Q9UHD9 UBQLN2	1	UBQLN2 [cytosol] (R-HSA-8866007)	0.556	3
UniProt:Q05329 GAD2	2	PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888582) PXLP-K396-GAD2 [plasma membrane] (R-HSA-936509)	0.556	3
UniProt:Q5SQN1 SNP47			0.556	3
UniProt:Q17RD7 SYT16			0.556	3
UniProt:P40305-1 IFI27			0.556	3
UniProt:Q8WWC4 C2orf47	1	C2orf47 [mitochondrial inner membrane] (R-HSA-8949660)	0.556	3
UniProt:Q9HC62 SENP2	1	SENP2 [nucleoplasm] (R-HSA-2984298)	0.556	3
UniProt:Q96QA5 GSDMA			0.556	3
UniProt:Q9BQE5 APOL2			0.556	3
UniProt:Q6ZUI0 TPRG1			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q9UMS0 NFU1	1	NFU1 [mitochondrial matrix] (R-HSA-1362393)	0.556	3
UniProt:Q8WXG1 RSAD2	1	RSAD2 [endoplasmic reticulum membrane] (R-HSA-5624199)	0.556	3
UniProt:Q96BZ9 TBC1D20	1	TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6814813)	0.556	3
UniProt:Q9H237-2 Q9H2372			0.556	3
UniProt:Q92843 B2CL2			0.556	3
UniProt:P07204 THBD	1	THBD [plasma membrane] (R-HSA-141030)	0.556	3
UniProt:Q5XKP0 MICOS13	1	MIC13 (QIL1) [mitochondrial inner membrane] (R-HSA-8949561)	0.556	3
UniProt:Q5TGZ0 MICOS10	1	MINOS1 (MIC10) [mitochondrial inner membrane] (R-HSA-8949616)	0.556	3
UniProt:Q9NR28 DIABLO	2	DIABLO [mitochondrial intermembrane space] (R-HSA-64637) DIABLO [cytosol] (R-HSA-114298)	0.556	3

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