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ELL3 [nucleoplasm]
Stable Identifier
R-HSA-6807497
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RNA polymerase II elongation factor ELL3, ELL3_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
Integrator complex processes the 3' end of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Homo sapiens)
LEC [nucleoplasm] (Homo sapiens)
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
ELL3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HB65 ELL3
Gene Names
ELL3
Chain
chain:1-397
Reference Genes
BioGPS Gene:80237 ELL3
COSMIC (genes):ELL3 ELL3
CTD Gene:80237 ELL3
dbSNP Gene:80237 ELL3
ENSEMBL:ENSG00000128886 ELL3
HGNC:23113 ELL3
KEGG:hsa:80237 ELL3
Monarch:80237 ELL3
NCBI Gene:80237 ELL3
OMIM:609885 ELL3
UCSC:Q9HB65 ELL3
Reference Transcript
RefSeq:NM_025165.2 ELL3
Other Identifiers
11722636_a_at
16808345
219517_PM_at
219517_at
219518_PM_s_at
219518_s_at
3621622
3621624
3621625
3621626
3621627
3621628
3621629
3621630
3621631
3621632
3621633
3621634
3621635
3621636
3621637
3621638
3621639
3621640
3621641
3621642
3621643
3621644
3621645
3621646
3621647
60885_at
60886_g_at
7988212
80237
84543_at
A_23_P3237
A_24_P47988
GE83115
GO:0000987
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005829
GO:0006351
GO:0006354
GO:0006355
GO:0006366
GO:0006368
GO:0007283
GO:0008023
GO:0010717
GO:0016073
GO:0016607
GO:0022414
GO:0030054
GO:0030154
GO:0032786
GO:0032968
GO:0042771
GO:0042795
GO:0043226
GO:0045944
GO:0048863
GO:0050769
GO:0061351
GO:0072089
GO:0072331
GO:1901797
GO:1902166
GO:2000179
GO:2000648
HMNXSV003047918
ILMN_1771264
PH_hs_0022833
TC15002773.hg
g13376767_3p_at
Participates
as a member of
ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)
Inferred To
Ell3 [nucleoplasm]
(Mus musculus)
Ell3 [nucleoplasm]
(Rattus norvegicus)
Ell [nucleoplasm]
(Drosophila melanogaster)
ELL3 [nucleoplasm]
(Bos taurus)
ELL3 [nucleoplasm]
(Canis familiaris)
ELL3 [nucleoplasm]
(Sus scrofa)
ell-1 [nucleoplasm]
(Caenorhabditis elegans)
ell3 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000319359
,
ENSP00000320346
OpenTargets
ENSG00000128886
HPA
ENSG00000128886-ELL3
PRO
Q9HB65
Pharos - Targets
Q9HB65
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96JC9 EAF1
1
EAF1 [nucleoplasm]
(R-HSA-8932787)
0.8
8
UniProt:P42568 MLLT3
1
MLLT3 [nucleoplasm]
(R-HSA-8932789)
0.643
3
UniProt:Q96CJ1 EAF2
1
EAF2 [nucleoplasm]
(R-HSA-8932790)
0.527
3
UniProt:P55199 ELL
1
ELL [nucleoplasm]
(R-HSA-54257)
0.527
2
UniProt:Q9UHB7 AFF4
1
AFF4 [nucleoplasm]
(R-HSA-8932788)
0.527
3
UniProt:Q03111 MLLT1
1
MLLT1 [nucleoplasm]
(R-HSA-8932918)
0.527
4
UniProt:O60563 CCNT1
1
CCNT1 [nucleoplasm]
(R-HSA-51611)
0.527
3
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