Reactome | ELL3 [nucleoplasm]

ELL3 [nucleoplasm]

Stable Identifier

R-CFA-6807497

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

ELL3, E2RD67

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - RNA polymerase II transcribes snRNA genes (Canis familiaris)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
    - Integrator complex processes the 3' end of snRNA (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Canis familiaris)
      - LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        LEC [nucleoplasm] (Canis familiaris)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Canis familiaris)
        
        ELL3 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2RD67

Gene Names

ELL3

Reference Genes

ENSEMBL:ENSCAFG00000013343

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000013343 ELL3

Other Identifiers

487526

CfaAffx.20646.1.S1_at

GO:0000987

GO:0003674

GO:0003677

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0006354

GO:0006366

GO:0006368

GO:0006950

GO:0007165

GO:0008023

GO:0008150

GO:0008219

GO:0008283

GO:0009058

GO:0010717

GO:0030154

GO:0032786

GO:0032991

GO:0034641

GO:0042795

GO:0043226

GO:0045944

GO:0048856

GO:0048863

GO:0050769

GO:1901797

GO:1902166

GO:2000179

Participant Of

hasMember

ELL,ELL2,ELL3 [nucleoplasm]

Inferred From

ELL3 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000128886

Ensembl

ENSCAFG00000013343, ENSCAFP00000019667, ENSCAFT00000021180

VGNC

40308

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