Reactome | RPS15 [nucleoplasm]

RPS15 [nucleoplasm]

Stable Identifier

R-HSA-6798706

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 15, P11174, 40S ribosomal protein S15, RIG protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62841 RPS15

Gene Names

RPS15, RIG

Chain

initiator methionine:1, chain:2-145

Reference Genes

BioGPS Gene:6209 RPS15

COSMIC (genes):RPS15 RPS15

CTD Gene:6209 RPS15

dbSNP Gene:6209 RPS15

ENSEMBL:ENSG00000115268 RPS15

HGNC:10388 RPS15

KEGG Gene (Homo sapiens):6209 RPS15

Monarch:6209 RPS15

NCBI Gene:6209 RPS15

OMIM:180535 RPS15

UCSC:P62841 RPS15

Reference Transcript

RefSeq:NM_001018.4 RPS15

Other Identifiers

11757375_x_at

16856581

200819_s_at

2352562

2586800

2586801

2586802

3815730

3815734

3815741

3815742

3815744

39916_r_at

6209

8024299

A_23_P209152

GO:0000028

GO:0000056

GO:0000184

GO:0001649

GO:0002181

GO:0003674

GO:0003677

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0006413

GO:0006464

GO:0006605

GO:0006614

GO:0006810

GO:0006913

GO:0007165

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0015935

GO:0016020

GO:0019083

GO:0022607

GO:0022618

GO:0022626

GO:0022627

GO:0030154

GO:0030234

GO:0032991

GO:0034641

GO:0034655

GO:0042254

GO:0042274

GO:0043226

GO:0044403

GO:0045202

GO:0048856

GO:0065003

GO:0097371

GO:0097421

GO:1901798

GO:1904667

GO:1990948

ILMN_1691807

ILMN_2219131

ILMN_2219134

TC19000039.hg

g4506686_3p_a_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RPS15 [cytosol]

Inferred To

rps-15 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of RPS15 [nucleoplasm] (Xenopus tropicalis)

rps15 [nucleoplasm] (Danio rerio)

rps15 [nucleoplasm] (Dictyostelium discoideum)

RPS15 [nucleoplasm] (Bos taurus)

RPS15 [nucleoplasm] (Canis familiaris)

RPS15 [nucleoplasm] (Plasmodium falciparum)

RPS15 [nucleoplasm] (Saccharomyces cerevisiae)

rps1501 [nucleoplasm] (Schizosaccharomyces pombe)

rps1502 [nucleoplasm] (Schizosaccharomyces pombe)

RpS15 [nucleoplasm] (Drosophila melanogaster)

Homologues of RPS15 [nucleoplasm] (Bos taurus)

Homologues of RPS15 [nucleoplasm] (Schizosaccharomyces pombe)

Rps15 [nucleoplasm] (Mus musculus)

Rps15 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001009.1

OpenTargets

ENSG00000115268

HPA

ENSG00000115268-RPS15

GeneCards

P62841

Ensembl

ENSP00000467466, ENST00000592588, ENSG00000115268

PRO

P62841

Pharos - Targets

P62841

Orphanet

23639

GlyGen

P62841

PDB

6ZMO, 6ZMT, 4UG0, 6Z6L, 5VYC, 7K5I, 6Y57, 6Y0G, 6FEC, 6G5I, 6ZMI, 6QZP, 6ZXG, 6ZXF, 6XA1, 6IP5, 6OLI, 6ZXH, 6ZUO, 6Z6M, 6ZN5, 6ZXD, 6ZMW, 6Z6N, 6ZXE, 6G18, 6OLZ, 5T2C, 6G51, 6ZVH, 6G4W, 6OM7, 5AJ0, 6ZV6, 6IP6, 5LKS, 6Y2L, 6IP8, 6YBS, 5OA3, 6OM0, 6G4S, 6OLG, 6ZON, 4V6X, 6ZP4, 6ZME, 6G5H, 6ZVJ, 6G53, 6ZLW, 6ZOJ, 6ZM7, 7A09, 6OLE, 5A2Q, 6ZOL, 5FLX, 6OLF

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.783	9
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.607	3
UniProt:P62937 PPIA	5	PPIA [extracellular exosome] (R-HSA-6801538) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [extracellular region] (R-HSA-173646) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [cytosol] (R-HSA-173123)	0.556	3
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.527	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.527	9

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