Reactome | SALM3 [plasma membrane]

SALM3 [plasma membrane]

Stable Identifier

R-HSA-197883

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

LRFN4, Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor, LRFN4_HUMAN

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External Reference Information

External Reference

UniProt:Q6PJG9 LRFN4

Gene Names

LRFN4, SALM3

Chain

signal peptide:1-16, chain:17-635

Reference Genes

BioGPS Gene:78999 LRFN4

COSMIC (genes):LRFN4 LRFN4

CTD Gene:78999 LRFN4

dbSNP Gene:78999 LRFN4

ENSEMBL:ENSG00000173621 LRFN4

ENSEMBL_homo_sapiens_GENE:ENSG00000173621.9 LRFN4

HGNC:28456 LRFN4

KEGG Gene (Homo sapiens):78999 LRFN4

Monarch:78999 LRFN4

NCBI Gene:78999 LRFN4

OMIM:612810 LRFN4

UCSC:Q6PJG9 LRFN4

Reference Transcript

Other Identifiers

11722296_at

11722297_s_at

16727616

219491_3p_at

219491_PM_at

219491_at

238092_PM_at

238092_at

3336577

3336578

3336579

3336580

3336581

3336582

3336583

3336586

3336587

3336588

3336589

3336590

3336591

3336592

3336593

54986_at

78999

7941743

80420_at

A_14_P138952

A_23_P63980

A_33_P3280094

GE82766

GO:0005515

GO:0005886

GO:0007155

GO:0009986

GO:0016020

GO:0034330

GO:0043226

GO:0048856

GO:0098839

GO:0098978

GO:0098982

GO:0099151

GO:0099560

GO:1905606

HMNXSV003050078

Hs.148438.0.A1_3p_at

ILMN_1809417

PH_hs_0022645

PH_hs_0030807

TC11000675.hg

TC11002732.hg

g13128987_3p_at

g13128987_3p_s_at

Participates

as a candidate of

SALM2,3(SALM1,4) [plasma membrane] (Homo sapiens)

as a component of

SALM3:LAR-RPTPs [plasma membrane] (Homo sapiens)

as an input of

SALM3 binds LAR-RPTP (Homo sapiens)

as a member of

SALM1,2,3 [plasma membrane] (Homo sapiens)

Inferred To

Lrfn4 [plasma membrane] (Mus musculus)

Lrfn4 [plasma membrane] (Rattus norvegicus)

LRFN4 [plasma membrane] (Bos taurus)

LRFN4 [plasma membrane] (Canis familiaris)

kek5 [plasma membrane] (Drosophila melanogaster)

lrfn4 [plasma membrane] (Xenopus tropicalis)

unc-89 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_076941.2, XP_005274296.1

OpenTargets

ENSG00000173621

GeneCards

Q6PJG9

HPA

ENSG00000173621-LRFN4

Ensembl

ENSP00000312535, ENSG00000173621, ENST00000309602

PRO

Q6PJG9

Pharos - Targets

Q6PJG9

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.597	12
UniProt:P16333 NCK1	2	NCK1 [cytosol] (R-HSA-197954) NCK1 [plasma membrane] (R-HSA-202992)	0.597	10
UniProt:Q3LI66 KRTAP6-2	1	KRTAP6-2 [cytosol] (R-HSA-6810261)	0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
UniProt:P0DPK4 NT2NC			0.556	3
UniProt:Q7Z3S9 NT2NA			0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.527	2
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.462	3
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.462	3
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.462	3
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.462	3

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