Reactome | NPLOC4 [nucleoplasm]

NPLOC4 [nucleoplasm]

Stable Identifier

R-HSA-5654987

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nuclear protein localization protein 4 homolog, NPL4

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TAT6 NPLOC4

Gene Names

NPLOC4, KIAA1499, NPL4

Chain

initiator methionine:1, chain:2-608

Reference Genes

BioGPS Gene:55666 NPLOC4

COSMIC (genes):NPLOC4 NPLOC4

CTD Gene:55666 NPLOC4

dbSNP Gene:55666 NPLOC4

ENSEMBL:ENSG00000182446 NPLOC4

HGNC:18261 NPLOC4

KEGG Gene (Homo sapiens):55666 NPLOC4

Monarch:55666 NPLOC4

NCBI Gene:55666 NPLOC4

OMIM:606590 NPLOC4

UCSC:Q8TAT6 NPLOC4

Reference Transcript

Other Identifiers

0003800594

11733893_a_at

11755047_a_at

11755406_x_at

11761364_a_at

16849882

217796_s_at

3774030

3774031

3774032

3774033

3774034

3774035

3774036

3774037

3774038

3774039

3774040

3774042

3774043

3774045

3774059

3774060

3774063

3774064

3774066

3774074

3774075

3774077

3774079

3774084

3774085

3774087

3774090

3774095

55666

61951_at

65788_at

8019211

90976_at

A_23_P72044

A_33_P3238966

GE55586

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0005829

GO:0006259

GO:0006511

GO:0006810

GO:0006950

GO:0007030

GO:0007165

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0019899

GO:0030433

GO:0030970

GO:0031625

GO:0032182

GO:0032480

GO:0032991

GO:0034098

GO:0034641

GO:0036501

GO:0039536

GO:0042175

GO:0043130

GO:0043161

GO:0043167

GO:0043226

GO:0046872

GO:0070987

HMNXSV003026832

ILMN_1807600

PH_hs_0023960

TC17001954.hg

g8923608_3p_a_at

Participates

as a component of

NPLOC4:UFD1L:VCP [nucleoplasm] (Homo sapiens)

Other forms of this molecule

NPLOC4 [cytosol]

Inferred To

NPL4 [nucleoplasm] (Saccharomyces cerevisiae)

NPLOC4 [nucleoplasm] (Bos taurus)

NPLOC4 [nucleoplasm] (Canis familiaris)

NPLOC4 [nucleoplasm] (Gallus gallus)

NPLOC4 [nucleoplasm] (Sus scrofa)

Nploc4 [nucleoplasm] (Mus musculus)

Nploc4 [nucleoplasm] (Rattus norvegicus)

Npl4 [nucleoplasm] (Drosophila melanogaster)

npl-4.2 [nucleoplasm] (Caenorhabditis elegans)

npl4 [nucleoplasm] (Schizosaccharomyces pombe)

nploc4 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_060391.2, XP_011523281.1

OpenTargets

ENSG00000182446

GeneCards

Q8TAT6

HPA

ENSG00000182446-NPLOC4

Ensembl

ENST00000374747, ENSP00000331487, ENSG00000182446, ENSP00000363879, ENST00000331134

PRO

Q8TAT6

Pharos - Targets

Q8TAT6

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55072 VCP	8	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) VCP [nucleoplasm] (R-HSA-5643745) VCP [secretory granule lumen] (R-HSA-6801039) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [cytosol] (R-HSA-1181251)	0.848	9
UniProt:P37173 TGFBR2	9	TGFBR2 Y470D [plasma membrane] (R-HSA-3640905) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 K128fs3 [cytosol] (R-HSA-3642173) TGFBR2 K128fs35 [cytosol] (R-HSA-3642166) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 [plasma membrane] (R-HSA-170842)	0.556	3
UniProt:O94888 UBXN7	2	UBXN7 [cytosol] (R-HSA-8956071) ub-UBXN7 [cytosol] (R-HSA-9755305)	0.499	5

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