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MonoUb-K164-PCNA [nucleoplasm]
Stable Identifier
R-HSA-5651986
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Icon
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Recognition of DNA damage by PCNA-containing replication complex (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 binds monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
TRIM25 binds monoUb:164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion Synthesis by POLH (Homo sapiens)
Elongation by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Insertion of correct bases opposite the lesion by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLI (Homo sapiens)
POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLZ elongates POLI-incorporated dNMP (Homo sapiens)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLK (Homo sapiens)
POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by REV1 (Homo sapiens)
POLZ extends translesion synthesis (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 binds AP-dsDNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 inserts dCMP opposite to AP sites in DNA (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in GG-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
HLTF binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
HLTF polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12004 PCNA
Gene Names
PCNA
Chain
chain:1-261
Reference Genes
BioGPS Gene:5111 PCNA
COSMIC (genes):PCNA PCNA
CTD Gene:5111 PCNA
dbSNP Gene:5111 PCNA
ENSEMBL:ENSG00000132646 PCNA
HGNC:8729 PCNA
KEGG:hsa:5111 PCNA
Monarch:5111 PCNA
NCBI Gene:5111 PCNA
OMIM:176740 PCNA
UCSC:P12004 PCNA
Reference Transcript
RefSeq:NM_182649.1 PCNA
RefSeq:NM_002592.2 PCNA
Other Identifiers
11716103_a_at
16916958
1824_s_at
1884_s_at
201202_PM_at
201202_at
3896201
3896202
3896203
3896204
3896206
3896207
3896209
3896211
3896213
3896214
3896215
3896216
4006657
4006658
5111
8064844
A_23_P28886
A_33_P3258612
GE61312
GO:0000122
GO:0000307
GO:0000701
GO:0000781
GO:0000785
GO:0001673
GO:0003677
GO:0003682
GO:0003684
GO:0003824
GO:0005515
GO:0005634
GO:0005652
GO:0005654
GO:0005657
GO:0005813
GO:0005815
GO:0006260
GO:0006272
GO:0006275
GO:0006281
GO:0006287
GO:0006298
GO:0006355
GO:0006979
GO:0007507
GO:0016604
GO:0016787
GO:0019899
GO:0019985
GO:0022414
GO:0030154
GO:0030331
GO:0030337
GO:0030855
GO:0030894
GO:0030971
GO:0031297
GO:0032077
GO:0032139
GO:0032200
GO:0032355
GO:0032405
GO:0033993
GO:0034644
GO:0035035
GO:0042802
GO:0043226
GO:0043596
GO:0043626
GO:0044849
GO:0044877
GO:0045739
GO:0045740
GO:0046686
GO:0048856
GO:0070062
GO:0070182
GO:0070301
GO:0070557
GO:0071466
GO:0071548
GO:0097421
GO:0098772
GO:0140097
GO:1900264
GO:1902065
GO:1902990
HMNXSV003000505
HMNXSV003026895
ILMN_1685682
ILMN_1694177
ILMN_1706958
J05614_at
M15796_at
PH_hs_0028994
TC20000592.hg
g4505640_3p_at
Participates
as a component of
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Other forms of this molecule
PCNA [nucleoplasm]
ISG-K164,ISG-K168-PCNA [nucleoplasm]
K63polyUb-K164-PCNA [nucleoplasm]
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
Inferred To
PCNA [nucleoplasm]
(Bos taurus)
PCNA [nucleoplasm]
(Canis familiaris)
PCNA [nucleoplasm]
(Drosophila melanogaster)
PCNA [nucleoplasm]
(Gallus gallus)
PCNA [nucleoplasm]
(Sus scrofa)
PCNA1 [nucleoplasm]
(Plasmodium falciparum)
pcna [nucleoplasm]
(Danio rerio)
pcna [nucleoplasm]
(Dictyostelium discoideum)
pcna [nucleoplasm]
(Xenopus tropicalis)
Pcna [nucleoplasm]
(Mus musculus)
Pcna [nucleoplasm]
(Rattus norvegicus)
POL30 [nucleoplasm]
(Saccharomyces cerevisiae)
pcn-1 [nucleoplasm]
(Caenorhabditis elegans)
pcn1 [nucleoplasm]
(Schizosaccharomyces pombe)
Modified Residues
Name
ubiquitinylated lysine at 164
Coordinate
164
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_872590.1
,
NP_002583.1
ZINC - World Drugs
PCNA_HUMAN
OpenTargets
ENSG00000132646
ENSEMBL
ENSP00000368458
,
ENSP00000368438
,
ENST00000379143
,
ENST00000379160
ZINC - FDA approved
PCNA_HUMAN
ZINC - Substances
PCNA_HUMAN
ZINC - Biogenic
PCNA_HUMAN
ZINC target
P12004
PRO
P12004
GlyGen
P12004
PDB
6CBI
,
6S1O
,
6TNY
,
6S1M
,
5E0U
,
3JA9
,
1W60
,
5MLO
,
7EFA
,
5YCO
,
8UI9
,
7KQ1
,
7QNZ
,
8F5Q
,
7NV1
,
6QCG
,
1VYM
,
2ZVK
,
6QC0
,
2ZVM
,
4D2G
,
8UI8
,
5MAV
,
5IY4
,
8UMT
,
8UMV
,
8GL9
,
6GIS
,
1UL1
,
7M5M
,
3TBL
,
3P87
,
1U7B
,
6VVO
,
5MOM
,
6EHT
,
6S1N
,
1U76
,
5E0T
,
4RJF
,
8B8T
,
5YD8
,
3VKX
,
5E0V
,
6TNZ
,
3WGW
,
8E84
,
8GLA
,
7NV0
,
8UN0
,
5MLW
,
8UII
,
2ZVL
,
1AXC
,
8COB
,
7KQ0
,
6GWS
,
8UI7
,
7QO1
,
8UMY
,
8UMU
,
6K3A
,
6FCM
,
8UMW
,
6FCN
,
7M5N
,
6HVO
,
7M5L
,
1VYJ
,
8GCJ
,
4ZTD
ZINC - Metabolites
PCNA_HUMAN
HPA
ENSG00000132646-PCNA
Pharos - Targets
P12004
Orphanet
PCNA
ZINC - Predictions - Purchasable
PCNA_HUMAN
Interactors (56)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38936 CDKN1A
5
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
CDKN1A [nucleoplasm]
(R-HSA-182585)
CDKN1A [cytosol]
(R-HSA-182512)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
0.977
39
UniProt:P39748 FEN1
1
FEN1 [nucleoplasm]
(R-HSA-54745)
0.964
22
UniProt:P12004 PCNA
5
PCNA [nucleoplasm]
(R-HSA-68439)
MonoUb-K164-PCNA [nucleoplasm]
(R-HSA-5651986)
ISG-K164,ISG-K168-PCNA [nucleoplasm]
(R-HSA-5653768)
K63polyUb-K164-PCNA [nucleoplasm]
(R-HSA-8943000)
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
(R-HSA-4615861)
0.898
11
UniProt:Q15054 POLD3
1
POLD3 [nucleoplasm]
(R-HSA-68445)
0.83
7
IntAct:EBI-4399559 UBIQ
0.811
7
UniProt:Q15004 PCLAF
2
KIAA0101 [nucleoplasm]
(R-HSA-5655178)
MonoUb-K15,K24-KIAA0101 [nucleoplasm]
(R-HSA-5655182)
0.8
7
UniProt:Q13111 CAF1A
0.734
4
UniProt:P20585 MSH3
2
MSH3 K383Rfs*32 [nucleoplasm]
(R-HSA-5578664)
MSH3 [nucleoplasm]
(R-HSA-5357519)
0.718
6
UniProt:P49005 POLD2
1
POLD2 [nucleoplasm]
(R-HSA-68443)
0.678
3
UniProt:O95944 NCR2
1
NCR2 [plasma membrane]
(R-HSA-197652)
0.672
7
UniProt:P28340 POLD1
2
POLD1 [cytosol]
(R-HSA-2564763)
POLD1 [nucleoplasm]
(R-HSA-68449)
0.669
3
UniProt:A2RU14 TM218
0.666
4
UniProt:Q9Z111 GA45G
0.664
9
UniProt:P24941 CDK2
5
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
CDK2 [nucleoplasm]
(R-HSA-68365)
CDK2 [cytosol]
(R-HSA-157440)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
0.643
4
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
14
UniProt:P42771 CDKN2A
20
p16INK4A D84G [cytosol]
(R-HSA-9632461)
p16INK4A E88* [cytosol]
(R-HSA-9632588)
p16INK4A R87P [cytosol]
(R-HSA-9632335)
p16INK4A V126D [cytosol]
(R-HSA-9631055)
p16INK4A W110* [cytosol]
(R-HSA-9632585)
p16INK4A D84H [cytosol]
(R-HSA-9632489)
p16INK4A R80* [cytosol]
(R-HSA-9632586)
p16INK4A P114L [cytosol]
(R-HSA-9630916)
p16INK4A R58* [cytosol]
(R-HSA-9632582)
p16INK4A D84N [cytosol]
(R-HSA-9632483)
p16INK4A M53I [cytosol]
(R-HSA-9630911)
p16INK4A D84Y [cytosol]
(R-HSA-9632478)
p16INK4A G101W [cytosol]
(R-HSA-9631257)
p16INK4A P81L [cytosol]
(R-HSA-9632280)
p16INK4A A20P [cytosol]
(R-HSA-9630805)
p16INK4A D84V [cytosol]
(R-HSA-9632465)
p16INK4A P81T [cytosol]
(R-HSA-9632275)
p16INK4A P81H [cytosol]
(R-HSA-9632293)
p16INK4A D84A [cytosol]
(R-HSA-9632486)
p16INK4A P81R [cytosol]
(R-HSA-9632294)
0.61
8
UniProt:Q5FWF4 ZRAB3
0.599
8
UniProt:P24385 CCND1
4
CCND1 [nucleoplasm]
(R-HSA-113832)
CCND1 [cytosol]
(R-HSA-68328)
p-T286-CCND1 [cytosol]
(R-HSA-75813)
p-T286-CCND1 [nucleoplasm]
(R-HSA-75811)
0.59
2
UniProt:P24522 GADD45A
1
GADD45A [nucleoplasm]
(R-HSA-3215139)
0.589
3
UniProt:Q9H063 MAF1
3
p-S60,S68,S75-MAF1 [cytosol]
(R-HSA-8944455)
MAF1 [cytosol]
(R-HSA-8944460)
MAF1 [nucleoplasm]
(R-HSA-8944422)
0.581
4
UniProt:P30041 PRDX6
3
PRDX6 [cytosol]
(R-HSA-3343670)
PRDX6 [extracellular region]
(R-HSA-6806198)
PRDX6 [azurophil granule lumen]
(R-HSA-6798744)
0.573
2
UniProt:P07355 ANXA2
6
ANXA2 [azurophil granule lumen]
(R-HSA-6798766)
ANXA2 [extracellular region]
(R-HSA-6806242)
p-S26-ANXA2 [cytosol]
(R-HSA-9865163)
p-Y24,S26-ANXA2 [cytosol]
(R-HSA-9865224)
ANXA2 [external side of plasma membrane]
(R-HSA-5336164)
ANXA2 [cytosol]
(R-HSA-5263667)
0.573
2
UniProt:P00558 PGK1
1
PGK1 [cytosol]
(R-HSA-70483)
0.573
2
UniProt:P68104 EEF1A1
7
EEF1A1 [lysosomal membrane]
(R-HSA-9626022)
EEF1A1 [cytosol]
(R-HSA-156905)
EEF1A1 [secretory granule lumen]
(R-HSA-6801479)
EEF1A1 [extracellular region]
(R-HSA-6806456)
EEF1A1 [ficolin-1-rich granule lumen]
(R-HSA-6801528)
Me3K318-EEF1A1 [cytosol]
(R-HSA-8932419)
Me3K79-EEF1A1 [cytosol]
(R-HSA-8932212)
0.573
2
UniProt:P61769 B2M
11
B2M(21-119) [plasma membrane]
(R-HSA-167743)
B2M(21-119) [endoplasmic reticulum lumen]
(R-HSA-983063)
B2M(21-119) [specific granule lumen]
(R-HSA-6806144)
B2M(21-119) [extracellular region]
(R-HSA-1302721)
B2M(21-119) [tertiary granule lumen]
(R-HSA-6800179)
B2M(21-119) [Golgi membrane]
(R-HSA-983403)
B2M(21-119) [ER to Golgi transport vesicle membrane]
(R-HSA-983378)
B2M(21-119) [early endosome lumen]
(R-HSA-1236827)
B2M(21-119) [recycling endosome membrane]
(R-HSA-8863880)
B2M(21-119) [phagocytic vesicle membrane]
(R-HSA-1236891)
B2M(21-119) [early endosome membrane]
(R-HSA-182298)
0.573
3
UniProt:P04075 ALDOA
6
ALDOA [platelet alpha granule lumen]
(R-HSA-349738)
ALDOA [ficolin-1-rich granule lumen]
(R-HSA-6801521)
ALDOA [tertiary granule lumen]
(R-HSA-6801485)
ALDOA [extracellular region]
(R-HSA-349735)
ALDOA [secretory granule lumen]
(R-HSA-6801469)
ALDOA [cytosol]
(R-HSA-71492)
0.571
3
UniProt:P04406 GAPDH
1
GAPDH [cytosol]
(R-HSA-70428)
0.571
3
UniProt:P06733 ENO1
1
ENO1 [cytosol]
(R-HSA-71437)
0.571
3
UniProt:Q14527 HLTF
1
HLTF [nucleoplasm]
(R-HSA-8855007)
0.564
2
UniProt:P61970 NTF2
0.556
3
UniProt:Q9NZD8 SPG21
0.556
3
UniProt:Q96DZ9-2 CMTM5
0.556
3
UniProt:Q8IWU4 SLC30A8
2
SLC30A8 [Golgi membrane]
(R-HSA-9817561)
SLC30A8 [secretory granule membrane]
(R-HSA-437106)
0.556
3
UniProt:P03129 VE7
0.547
2
UniProt:A8CG34 POM121C
1
POM121C [nuclear envelope]
(R-HSA-6805165)
0.547
2
UniProt:Q8IWL3 HSCB
5
HSCB [mitochondrial matrix]
(R-HSA-1299438)
HSCB(1-30) [mitochondrial matrix]
(R-HSA-8986120)
HSCB(1-235) [mitochondrial inner membrane]
(R-HSA-1299443)
HSCB [mitochondrial inner membrane]
(R-HSA-1299447)
HSCB(1-235) [mitochondrial intermembrane space]
(R-HSA-1299456)
0.547
2
UniProt:P18669 PGAM1
4
PGAM1 [cytosol]
(R-HSA-71442)
PGAM1 [secretory granule lumen]
(R-HSA-6803293)
PGAM1 [extracellular region]
(R-HSA-6806482)
PGAM1 [ficolin-1-rich granule lumen]
(R-HSA-6803309)
0.544
2
UniProt:Q9H160 ING2
2
monoSUMO1-K195-ING2 [nucleoplasm]
(R-HSA-4086075)
ING2 [nucleoplasm]
(R-HSA-3215167)
0.544
3
UniProt:P60174 TPI1
1
TPI1 [cytosol]
(R-HSA-70451)
0.544
2
UniProt:P03950 ANG
2
ANG [extracellular region]
(R-HSA-5692435)
ANG [cytosol]
(R-HSA-9708345)
0.537
4
UniProt:P35249 RFC4
1
RFC4 [nucleoplasm]
(R-HSA-68429)
0.527
2
UniProt:P24864 CCNE1
3
CCNE1 [nucleoplasm]
(R-HSA-68363)
CCNE1 [cytosol]
(R-HSA-157443)
Unfolded CCNE1 [cytosol]
(R-HSA-6813836)
0.527
3
UniProt:P35250 RFC2
1
RFC2 [nucleoplasm]
(R-HSA-68433)
0.527
2
UniProt:O96020 CCNE2
3
Unfolded CCNE2 [cytosol]
(R-HSA-6813844)
CCNE2 [cytosol]
(R-HSA-157452)
CCNE2 [nucleoplasm]
(R-HSA-68367)
0.527
3
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P52701 MSH6
2
MSH6 L222* [nucleoplasm]
(R-HSA-5632954)
MSH6 [nucleoplasm]
(R-HSA-5357528)
0.527
2
UniProt:P20248 CCNA2
3
CCNA2 [nucleoplasm]
(R-HSA-68905)
CCNA2 [cytosol]
(R-HSA-157444)
PolyUb-CCNA2 [nucleoplasm]
(R-HSA-6783099)
0.527
3
UniProt:P14635 CCNB1
4
CCNB1 [nucleoplasm]
(R-HSA-68901)
p-4S-CCNB1 [cytosol]
(R-HSA-170058)
p-4S-CCNB1 [nucleoplasm]
(R-HSA-170049)
CCNB1 [cytosol]
(R-HSA-157451)
0.527
3
UniProt:Q9HCU8 POLD4
1
POLD4 [nucleoplasm]
(R-HSA-68447)
0.524
4
UniProt:B4URF7 B4URF7
0.508
2
UniProt:Q86TU7 SETD3
1
SETD3 [nucleoplasm]
(R-HSA-5688411)
0.508
3
UniProt:Q1K9H5 Q1K9H5
0.508
2
UniProt:Q9UBF6 RNF7
1
RNF7 (RBX2) [cytosol]
(R-HSA-8863132)
0.508
3
UniProt:Q8TE30 Q8TE30
0.499
6
UniProt:Q9H211 CDT1
1
CDT1 [nucleoplasm]
(R-HSA-68536)
0.499
2
UniProt:P57081 WDR4
1
WDR4 [nucleoplasm]
(R-HSA-6782341)
0.462
3
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