polySUMO2,3-K409,K447-NR1H2 [nucleoplasm]

Stable Identifier
R-HSA-4720435
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SUMO2,3-Oxysterols receptor LXR-beta, NR1H2_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
17218271 Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

Ghisletti, S, Pascual, G, Huang, W, Lin, ME, Willson, TM, Ogawa, S, Rosenfeld, MG, Glass, CK

Mol. Cell 2007
External Reference Information
External Reference
UniProt:P55055 NR1H2
Gene Names
NR1H2, LXRB, NER, UNR
Chain
chain:1-460
Reference Genes
BioGPS Gene:7376 NR1H2
COSMIC (genes):NR1H2 NR1H2
CTD Gene:7376 NR1H2
dbSNP Gene:7376 NR1H2
ENSEMBL:ENSG00000131408 NR1H2
HGNC:7965 NR1H2
KEGG:hsa:7376 NR1H2
Monarch:7376 NR1H2
NCBI Gene:7376 NR1H2
OMIM:600380 NR1H2
UCSC:P55055 NR1H2
Reference Transcript
Other Identifiers
11748768_x_at
11751235_a_at
11757339_x_at
16864472
218215_PM_s_at
218215_s_at
3839277
3839278
3839279
3839280
3839283
3839284
3839285
3839286
3839287
3839288
3839289
3839290
3839291
3839292
3839293
3839294
3839295
3839296
3839297
3839298
3839299
3839300
3839301
3839302
3839303
3839304
518_at
519_g_at
7376
8030630
A_23_P55926
A_23_P67332
A_33_P3356637
GE58888
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003700
GO:0004879
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006629
GO:0008270
GO:0009755
GO:0010745
GO:0010867
GO:0010875
GO:0010884
GO:0010887
GO:0016071
GO:0030154
GO:0030522
GO:0031490
GO:0032369
GO:0032376
GO:0034191
GO:0036151
GO:0042632
GO:0042789
GO:0043226
GO:0043565
GO:0044255
GO:0045723
GO:0045861
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0046965
GO:0048550
GO:0051006
GO:0051117
GO:0051247
GO:0055088
GO:0060089
GO:0060336
GO:0090108
GO:0090187
GO:0090340
GO:0090575
GO:0120163
GO:0140110
GO:1902895
GO:1903573
HMNXSV003054082
ILMN_1678032
PH_hs_0028409
TC19000756.hg
U07132_at
g11321629_3p_a_at
Participates
as a component of
Other forms of this molecule
NR1H2 [nucleoplasm]
NR1H2 [cytosol]
Inferred To
NR1H2 [nucleoplasm] (Bos taurus)
NR1H2 [nucleoplasm] (Sus scrofa)
EcR [nucleoplasm] (Drosophila melanogaster)
nr1h2 [nucleoplasm] (Xenopus tropicalis)
Nr1h2 [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Rattus norvegicus)
Modified Residues
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 409
Coordinate
409
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 447
Coordinate
447
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
Guide to Pharmacology - Targets
601
OpenTargets
ENSEMBL
HPA
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
Pharos - Targets
GlyGen
ZINC - Predictions - Purchasable
PDB
Interactors (2)
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