SUMO1-K108-RXRA [nucleoplasm]

Stable Identifier
R-HSA-4341130
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Retinoic acid receptor RXR-alpha, RXRA_HUMAN
SUMO1-K108-RXRA [nucleoplasm] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16912044 Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1

Choi, SJ, Chung, SS, Rho, EJ, Lee, HW, Lee, MH, Choi, HS, Seol, JH, Baek, SH, Bang, OS, Chung, CH

J. Biol. Chem. 2006
External Reference Information
External Reference
Gene Names
RXRA, NR2B1
Chain
chain:1-462
Other Identifiers
0001850017
11742843_a_at
11742844_a_at
17090917
202426_s_at
202449_s_at
3193370
3193371
3193372
3193390
3193393
3193396
3193399
3193400
3193408
3193410
3193412
3193413
3193414
3193415
3193416
3193418
32800_at
405_at
6256
8159127
A_14_P104460
A_23_P219176
A_23_P423197
GE61154
GO:0000003
GO:0000122
GO:0000228
GO:0000790
GO:0000977
GO:0000978
GO:0000981
GO:0001162
GO:0001701
GO:0001890
GO:0001893
GO:0001972
GO:0003674
GO:0003677
GO:0003690
GO:0003700
GO:0003707
GO:0003713
GO:0004879
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005739
GO:0006355
GO:0006357
GO:0006367
GO:0006412
GO:0006629
GO:0006766
GO:0006810
GO:0007165
GO:0007507
GO:0007566
GO:0008134
GO:0008150
GO:0008203
GO:0008270
GO:0008283
GO:0008289
GO:0009058
GO:0009790
GO:0015721
GO:0016032
GO:0016922
GO:0019048
GO:0019216
GO:0019899
GO:0030154
GO:0031490
GO:0032526
GO:0032991
GO:0034641
GO:0035357
GO:0038023
GO:0040007
GO:0042277
GO:0042802
GO:0042809
GO:0043010
GO:0043167
GO:0043226
GO:0043235
GO:0043401
GO:0043565
GO:0044212
GO:0044281
GO:0044323
GO:0044403
GO:0045893
GO:0045944
GO:0045994
GO:0046872
GO:0048384
GO:0048856
GO:0050692
GO:0050693
GO:0055010
GO:0055012
GO:0060038
GO:0060528
GO:0060687
GO:0070644
GO:0090575
Hs.20084.0.S1_3p_a_at
ILMN_1687315
PH_hs_0001748
TC09000782.hg
X52773_at
g10862707_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
Inter-chain Crosslink via sumoylated lysine at 108 and 97
Coordinate
108
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (24)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P10276 RARA  3 0.952 15
 UniProt:Q15788 NCOA1  3 0.857 14
 UniProt:P11473 VDR  2 0.791 6
 UniProt:Q15596 NCOA2  3 0.775 5
 UniProt:P37231-1 PPARG      0.715 6
 UniProt:Q15648 MED1  1 0.697 6
 UniProt:P04625 THA      0.65 4
 UniProt:Q71SY5 MED25  1 0.625 4
 UniProt:Q13133 NR1H3  1 0.609 8
 ChEBI:9352 SULINDAC      0.602 3
 UniProt:P27986 PIK3R1  15 0.556 8
 UniProt:O14503 BHLHE40  1 0.556 4
 UniProt:P97792-1 CXADR      0.544 2
 IntAct:EBI-15743714 COACTIVATOR PEPTIDE      0.544 2
 IntAct:EBI-11173936 P2      0.524 4
 IntAct:EBI-11173957 P4      0.524 4
 IntAct:EBI-11173879 P1      0.524 4
 UniProt:Q03463-PRO_0000278730      0.524 3
 IntAct:EBI-11173918 IR1      0.524 2
 UniProt:Q9JLI4 NCOA6      0.508 2
 UniProt:P42224 STAT1  7 0.508 2
 IntAct:EBI-10055663 CP2C8      0.499 5
 IntAct:EBI-10055402 PXR-RE      0.499 3
 IntAct:EBI-10055654 CP2C8      0.499 5
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