Reactome | Nr1h2 [nucleoplasm]

Nr1h2 [nucleoplasm]

Stable Identifier

R-RNO-4720435

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

polySUMO2,3-K409,K447-NR1H2, Q62755

Locations in the PathwayBrowser

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Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - SUMOylation (Rattus norvegicus)
    - SUMO E3 ligases SUMOylate target proteins (Rattus norvegicus)
      - SUMOylation of intracellular receptors (Rattus norvegicus)
        
        HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Rattus norvegicus)
        
        SUMO2,3-NR1H2:hydroxycholesterol [nucleoplasm] (Rattus norvegicus)
        
        Nr1h2 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q62755

Gene Names

Nr1h2

Reference Genes

BioGPS Gene:58851 Nr1h2

ENSEMBL:ENSRNOG00000019812

ENSEMBL:ENSRNOG00055005528

ENSEMBL:ENSRNOG00060007205

ENSEMBL:ENSRNOG00065027607

KEGG:rno:58851 Nr1h2

Monarch:58851 Nr1h2

NCBI Gene:58851 Nr1h2

UCSC:Q62755 Nr1h2

Reference Transcript

Other Identifiers

10721421

1370208_at

17632454

5628571

5665960

5677993

5775971

5884551

58851

6041286

6120049

6256727

6306013

6312619

6343902

6393388

6396764

6715052

A_44_P474165

GE20864

GO:0000122

GO:0000978

GO:0000981

GO:0001228

GO:0003677

GO:0003700

GO:0004879

GO:0005634

GO:0005737

GO:0006355

GO:0006357

GO:0006629

GO:0008270

GO:0010867

GO:0010875

GO:0010884

GO:0010887

GO:0030522

GO:0031490

GO:0032369

GO:0032376

GO:0034191

GO:0036151

GO:0042632

GO:0043565

GO:0045723

GO:0045861

GO:0045892

GO:0045893

GO:0045944

GO:0046872

GO:0046965

GO:0048550

GO:0051117

GO:0055088

GO:0090108

GO:0090187

GO:0090340

GO:0090575

GO:0120163

GO:1902895

GO:1903573

ILMN_1367664

PH_rn_0004069

U14533_at

Participates

as a component of

SUMO2,3-NR1H2:hydroxycholesterol [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

Nr1h2 [cytosol]

Nr1h2 [nucleoplasm]

Inferred From

polySUMO2,3-K409,K447-NR1H2 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 409 (in Homo sapiens)

Coordinate

409

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 447 (in Homo sapiens)

Coordinate

447

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_113814.2, NP_001385539.1, NP_001385538.1

ENSEMBL

ENSRNOT00000026862, ENSRNOP00000026862, ENSRNOG00000019812

PRO

Q62755

RGD

61906

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