TTP:mRNA Complex [cytosol]

Stable Identifier
R-HSA-450365
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12324455 RNA binding properties of the AU-rich element-binding recombinant Nup475/TIS11/tristetraprolin protein

Worthington, MT, Pelo, JW, Sachedina, MA, Applegate, JL, Arseneau, KO, Pizarro, TT

J Biol Chem 2002
18367721 Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation

Emmons, J, Townley-Tilson, WH, Deleault, KM, Skinner, SJ, Gross, RH, Whitfield, ML, Brooks, SA

RNA 2008
15117938 RNA sequence elements required for high affinity binding by the zinc finger domain of tristetraprolin: conformational changes coupled to the bipartite nature of Au-rich MRNA-destabilizing motifs

Brewer, BY, Malicka, J, Blackshear, PJ, Wilson, GM

J Biol Chem 2004
12705825 Selective RNA binding by a single CCCH zinc-binding domain from Nup475 (Tristetraprolin)

Michel, SL, Guerrerio, AL, Berg, JM

Biochemistry 2003
12639954 Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates

Blackshear, PJ, Lai, WS, Kennington, EA, Brewer, G, Wilson, GM, Guan, X, Zhou, P

J Biol Chem 2003
10330172 Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA

Lai, WS, Carballo, E, Strum, JR, Kennington, EA, Phillips, RS, Blackshear, PJ

Mol Cell Biol 1999
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