TTP:mRNA Complex [cytosol]

Stable Identifier
R-HSA-450365
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12705825 Selective RNA binding by a single CCCH zinc-binding domain from Nup475 (Tristetraprolin)

Michel, SL, Berg, JM, Guerrerio, AL

Biochemistry 2003
12639954 Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates

Brewer, G, Guan, X, Zhou, P, Kennington, EA, Lai, WS, Wilson, GM, Blackshear, PJ

J Biol Chem 2003
18367721 Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation

Deleault, KM, Gross, RH, Townley-Tilson, WH, Brooks, SA, Emmons, J, Whitfield, ML, Skinner, SJ

RNA 2008
10330172 Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA

Kennington, EA, Carballo, E, Lai, WS, Strum, JR, Phillips, RS, Blackshear, PJ

Mol Cell Biol 1999
12324455 RNA binding properties of the AU-rich element-binding recombinant Nup475/TIS11/tristetraprolin protein

Applegate, JL, Arseneau, KO, Pizarro, TT, Pelo, JW, Sachedina, MA, Worthington, MT

J Biol Chem 2002
15117938 RNA sequence elements required for high affinity binding by the zinc finger domain of tristetraprolin: conformational changes coupled to the bipartite nature of Au-rich MRNA-destabilizing motifs

Malicka, J, Wilson, GM, Brewer, BY, Blackshear, PJ

J Biol Chem 2004
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