TTP:mRNA Complex [cytosol]

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18367721 Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation

Deleault, KM, Gross, RH, Townley-Tilson, WH, Brooks, SA, Emmons, J, Whitfield, ML, Skinner, SJ

RNA 2008
12324455 RNA binding properties of the AU-rich element-binding recombinant Nup475/TIS11/tristetraprolin protein

Applegate, JL, Arseneau, KO, Pizarro, TT, Pelo, JW, Sachedina, MA, Worthington, MT

J Biol Chem 2002
15117938 RNA sequence elements required for high affinity binding by the zinc finger domain of tristetraprolin: conformational changes coupled to the bipartite nature of Au-rich MRNA-destabilizing motifs

Malicka, J, Wilson, GM, Brewer, BY, Blackshear, PJ

J Biol Chem 2004
12705825 Selective RNA binding by a single CCCH zinc-binding domain from Nup475 (Tristetraprolin)

Michel, SL, Berg, JM, Guerrerio, AL

Biochemistry 2003
12639954 Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates

Brewer, G, Guan, X, Zhou, P, Kennington, EA, Lai, WS, Wilson, GM, Blackshear, PJ

J Biol Chem 2003
10330172 Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA

Kennington, EA, Carballo, E, Lai, WS, Strum, JR, Phillips, RS, Blackshear, PJ

Mol Cell Biol 1999
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