mRNA Transcript Targeted by Tristetraproline [cytosol]

Stable Identifier
R-ALL-450597
Type
OtherEntity
Compartment
cytosol
Locations in the PathwayBrowser
for Species:
Expand all
General

Tristetraproline binds AU-rich elements in the following mRNAs: Tumor necrosis factor alpha (TNFA), Granulocyte-macrophage colony stimulating factor (CSF2, GM-CSF), Interleukin-2 (IL-2), and Proto-oncogene C-FOS (FOS, c-fos).

Literature References
PubMed ID Title Journal Year
17369404 TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

Franks, TM, Lykke-Andersen, J

Genes Dev 2007
17133347 Tristetraprolin recruits functional mRNA decay complexes to ARE sequences

Williams, DA, Walsh, RJ, Hau, HH, Ogilvie, RL, Bohjanen, PR, Reilly, CS

J Cell Biochem 2007
Participates
as a component of
as an input of
Cross References
ChEBI
Cite Us!