mRNA Transcript Targeted by Tristetraproline [cytosol]

Stable Identifier
R-ALL-450597
Type
OtherEntity
Compartment
cytosol
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General

Tristetraproline binds AU-rich elements in the following mRNAs: Tumor necrosis factor alpha (TNFA), Granulocyte-macrophage colony stimulating factor (CSF2, GM-CSF), Interleukin-2 (IL-2), and Proto-oncogene C-FOS (FOS, c-fos).

Literature References
PubMed ID Title Journal Year
17369404 TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

Franks, TM, Lykke-Andersen, J

Genes Dev 2007
17133347 Tristetraprolin recruits functional mRNA decay complexes to ARE sequences

Hau, HH, Walsh, RJ, Ogilvie, RL, Williams, DA, Reilly, CS, Bohjanen, PR

J Cell Biochem 2007
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