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What is Reactome ?
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VEGFA-165 [extracellular region]
Stable Identifier
R-HSA-4420127
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Vascular endothelial growth factor A, VEGFA_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
VEGFA-165 dimer binds VEGFA inhibitors (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer:VEGFA inhibitors [extracellular region] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
AXL autophosphorylates on Y779 and Y821 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
AXL binds SRC-1 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
BCAR1 binds p-7Y-PTK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1:BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
CDC42:GTP binds PAK2 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
CRK binds BCAR1 and or PXN (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
DOCK180:ELMO binds CRK (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
FYN autophosphorylates (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
FYN phosphorylates PAK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
HSP90AA1 binds p-6Y-VEGFR2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PAK2 autophorylates (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PAK2 binds NCK (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PTK2 autophosphorylates (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1:BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PTK2beta binds alphaVbeta3 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
PXN binds p-6Y,S732-PTK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
Phosphorylation of SRC-1 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SRC-1 binds p-Y397-PTK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SRC-1 phosphorylates PTK2-beta (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SRC-1 phosphorylates SHB (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SRC-1 phosphorylates p-Y397-PTK2 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
Src kinases phosphorylate VAV (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer binds VEGFA inhibitors (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer:VEGFA inhibitors [extracellular region] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer binds VEGFR2 dimer (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer:VEGFA inhibitors [extracellular region] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer:VEGFR2 [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFR2 autophosphorylates (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA-165 dimer:VEGFR2 [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFR2 mediated cell proliferation (Homo sapiens)
PLCG1 disassociates from VEGFR2 and translocate to PM (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
SFKs phosphorylate PLCG1 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds PLCG1 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds FYN (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds NCK (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds PI3K (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds SH2D2A (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds SHB (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-6Y-VEGFR2 binds SHC-transforming protein 2 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-AXL binds PI3K (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Homo sapiens)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p-Y420-FYN is phosphorylated on S21 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
p38 MAPK activation by VEGFR (Homo sapiens)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Homo sapiens)
VEGFA-165 dimer [extracellular region] (Homo sapiens)
VEGFA-165 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15692-4 VEGFA
Gene Names
VEGFA, VEGF
Participates
as a component of
VEGFA-165 dimer [extracellular region] (Homo sapiens)
Inferred To
vegfaa [extracellular region]
(Danio rerio)
Vegfa [extracellular region]
(Mus musculus)
Vegfa [extracellular region]
(Rattus norvegicus)
VEGFA-165 [extracellular region]
(Gallus gallus)
vegfa [extracellular region]
(Xenopus tropicalis)
VEGFA [extracellular region]
(Bos taurus)
VEGFA [extracellular region]
(Canis familiaris)
VEGFA [extracellular region]
(Sus scrofa)
Ghost homologue of VEGFA-165 [extracellular region]
(Caenorhabditis elegans)
Ghost homologue of VEGFA-165 [extracellular region]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001191314.1
,
NP_001191313.1
,
NP_001165100.1
,
NP_001028928.1
,
NP_001165101.1
,
NP_001020540.2
,
NP_001020541.2
,
NP_001273973.1
,
NP_001165099.1
,
NP_001020537.2
,
NP_001165098.1
,
NP_001020539.2
,
NP_001165097.1
,
NP_001020538.2
,
NP_001165096.1
,
NP_003367.4
,
NP_001165093.1
,
NP_001303939.1
,
NP_001165094.1
,
NP_001165095.1
OpenTargets
ENSG00000112715
ENSEMBL
ENST00000523950
,
ENST00000417285
,
ENST00000523873
,
ENSP00000430829
,
ENSP00000361125
,
ENSP00000361148
,
ENSP00000430002
,
ENSP00000500082
,
ENSP00000428321
,
ENSP00000388663
,
ENST00000482630
,
ENST00000372064
,
ENST00000672860
,
ENST00000372067
,
ENSP00000421561
,
ENST00000523125
,
ENSP00000317598
,
ENST00000520948
,
ENSP00000361137
,
ENSP00000430479
,
ENST00000372077
,
ENSG00000112715
,
ENSP00000429643
,
ENST00000324450
,
ENST00000518689
,
ENSP00000429008
,
ENST00000413642
,
ENST00000457104
,
ENSP00000409911
,
ENSP00000389864
,
ENST00000518824
,
ENSP00000361134
,
ENST00000372055
ZINC - Substances
VEGFA_HUMAN
ZINC - Biogenic
VEGFA_HUMAN
ZINC target
P15692
PRO
P15692
GlyGen
P15692
PDB
1KAT
,
5HHD
,
5FV1
,
1MJV
,
6BFT
,
5DN2
,
1VPF
,
1BJ1
,
6D3O
,
6ZCD
,
1CZ8
,
4WPB
,
2VPF
,
7LL8
,
6Z3F
,
3S1B
,
1TZI
,
7KEZ
,
5T89
,
3S1K
,
6ZBR
,
6Z13
,
4ZFF
,
3V2A
,
1VPP
,
1KMX
,
4QAF
,
7KF0
,
5HHC
,
5FV2
,
3P9W
,
7KF1
,
1MKG
,
3QTK
,
1MKK
,
2VGH
,
5O4E
,
3BDY
,
6V7K
,
4GLN
,
7LL9
,
4GLS
,
1TZH
,
6ZFL
,
1FLT
,
1QTY
,
4DEQ
,
2FJG
,
4KZN
,
2QR0
,
2FJH
,
6T9D
,
1VGH
ZINC - Metabolites
VEGFA_HUMAN
HPA
ENSG00000112715-VEGFA
GeneCards
VEGFA
Pharos - Targets
P15692
ZINC - Predictions - Purchasable
VEGFA_HUMAN
HMDB Protein
HMDBP02130
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17948 FLT1
1
VEGFR1 [plasma membrane]
(R-HSA-3004464)
0.819
5
UniProt:P35968 KDR
5
p-6Y-VEGFR2 [plasma membrane]
(R-HSA-4420103)
VEGFR2 [plasma membrane]
(R-HSA-195382)
p-Y801,Y1054,Y1175-KDR [plasma membrane]
(R-HSA-9860484)
VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) fusion [plasma membrane]
(R-HSA-9673613)
p-11Y-VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) [plasma membrane]
(R-HSA-9673636)
0.808
5
UniProt:P15692 VEGFA
2
VEGFA [extracellular region]
(R-HSA-2975974)
VEGFA [platelet alpha granule lumen]
(R-HSA-3132764)
0.719
10
UniProt:O14786 NRP1
1
NRP1 [plasma membrane]
(R-HSA-3008773)
0.697
4
UniProt:P49765 VEGFB
2
VEGFB [platelet alpha granule lumen]
(R-HSA-3132756)
VEGFB [extracellular region]
(R-HSA-2975973)
0.483
2
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