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Go!
VEGFB [extracellular region]
Stable Identifier
R-HSA-2975973
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Vascular endothelial growth factor B, VEGFB_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [extracellular region] (Homo sapiens)
VEGFs [extracellular region] (Homo sapiens)
VEGFB [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGF ligand-receptor interactions (Homo sapiens)
Homodimerization of VEGF proteins (Homo sapiens)
VEGF [extracellular region] (Homo sapiens)
VEGFB [extracellular region] (Homo sapiens)
VEGF dimer [extracellular region] (Homo sapiens)
VEGFB dimer [extracellular region] (Homo sapiens)
VEGFB [extracellular region] (Homo sapiens)
VEGF binds to VEGFR leading to receptor dimerization (Homo sapiens)
VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Homo sapiens)
VEGFA,VEGFB,PGF dimers [extracellular region] (Homo sapiens)
VEGFB dimer [extracellular region] (Homo sapiens)
VEGFB [extracellular region] (Homo sapiens)
VEGFR1 dimer:VEGFA, VEGFB, PGF dimers [plasma membrane] (Homo sapiens)
VEGFA,VEGFB,PGF dimers [extracellular region] (Homo sapiens)
VEGFB dimer [extracellular region] (Homo sapiens)
VEGFB [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49765 VEGFB
Gene Names
VEGFB, VRF
Chain
signal peptide:1-21, chain:22-207
Reference Genes
BioGPS Gene:7423 VEGFB
COSMIC (genes):VEGFB VEGFB
CTD Gene:7423 VEGFB
dbSNP Gene:7423 VEGFB
ENSEMBL:ENSG00000173511 VEGFB
ENSEMBL_homo_sapiens_GENE:ENSG00000173511.10 VEGFB
HGNC:12681 VEGFB
KEGG Gene (Homo sapiens):7423 VEGFB
Monarch:7423 VEGFB
NCBI Gene:7423 VEGFB
OMIM:601398 VEGFB
UCSC:P49765 VEGFB
Reference Transcript
RefSeq:NM_003377.4 VEGFB
RefSeq:NM_001243733.1 VEGFB
Other Identifiers
11717537_a_at
16726311
1926_at
203683_3p_s_at
203683_PM_s_at
203683_s_at
3334326
3334327
3334328
3334329
3334330
3334331
3334333
3334335
3334336
3334338
37268_at
7423
7940904
A_14_P127402
A_23_P1594
A_24_P55971
GE59164
GE80109
GO:0001666
GO:0001934
GO:0001938
GO:0002040
GO:0002376
GO:0003012
GO:0003013
GO:0005515
GO:0005576
GO:0005615
GO:0006486
GO:0006493
GO:0007165
GO:0007507
GO:0008083
GO:0008201
GO:0008284
GO:0010629
GO:0012501
GO:0016020
GO:0023052
GO:0030949
GO:0031093
GO:0031410
GO:0035470
GO:0036211
GO:0038084
GO:0042056
GO:0042060
GO:0042802
GO:0043066
GO:0043183
GO:0043226
GO:0043524
GO:0045766
GO:0048010
GO:0048018
GO:0048856
GO:0048870
GO:0050731
GO:0050918
GO:0050930
GO:0051781
GO:0051897
GO:0060048
GO:0060754
GO:0060976
GO:0070374
GO:0098772
GO:1901135
HMNXSV003015722
ILMN_1722855
ILMN_1726981
ILMN_1772274
ILMN_1801814
PH_hs_0004543
PH_hs_0035467
TC11000589.hg
g4507886_3p_at
g4507886_3p_s_at
Participates
as a member of
VEGFs [extracellular region] (Homo sapiens)
VEGF [extracellular region] (Homo sapiens)
as a component of
VEGFB dimer [extracellular region] (Homo sapiens)
Other forms of this molecule
VEGFB [platelet alpha granule lumen]
Inferred To
vegfaa [extracellular region]
(Danio rerio)
Vegfb [extracellular region]
(Mus musculus)
Vegfb [extracellular region]
(Rattus norvegicus)
vegfa [extracellular region]
(Xenopus tropicalis)
vegfb [extracellular region]
(Xenopus tropicalis)
Homologues of VEGFB [extracellular region]
(Xenopus tropicalis)
VEGFB [extracellular region]
(Bos taurus)
VEGFB [extracellular region]
(Canis familiaris)
VEGFB [extracellular region]
(Gallus gallus)
VEGFB [extracellular region]
(Sus scrofa)
Cross References
RefSeq
NP_001230662.1
,
NP_003368.1
OpenTargets
ENSG00000173511
GeneCards
P49765
HPA
ENSG00000173511-VEGFB
Ensembl
ENST00000426086
,
ENSG00000173511
,
ENSP00000311127
,
ENSP00000401550
,
ENST00000309422
PRO
P49765
Pharos - Targets
P49765
PDB
2XAC
,
2C7W
,
2VWE
,
6TKK
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15692 VEGFA
2
VEGFA [platelet alpha granule lumen]
(R-HSA-3132764)
VEGFA [extracellular region]
(R-HSA-2975974)
0.483
2
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