Translatable mRNA Complex [cytosol]

Stable Identifier
R-HSA-429977
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General

mRNA's that are ready for translation have a circular structure caused by interaction between PABP bound to the 3' poly(A) tail and the eIF4E-eIF4G-PAIP complex bound to the 7-methylguanosine cap. The interaction between poly(A)-PABP and the eIF4G-eIF4E complex stimulates affinity of eIF4E for the cap and improves translation.

Participants
Participant Of
Inferred To