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ROBO1:SLIT2 [plasma membrane]
Stable Identifier
R-HSA-390371
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Robo1:Slit2:Glypican-1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Activation of RAC1 (Homo sapiens)
Activation of RAC1 by SOS (Homo sapiens)
SLIT2:ROBO1:NCK:SOS [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
NCK binds ROBO1:SLIT2 (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Recruitment of PAK to NCK (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK:PAK [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Recruitment of SOS to plasma membrane (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK:SOS [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Ena/VASP proteins bind ROBO1:SLIT2 complex (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Inactivation of CDC42 and RAC1 (Homo sapiens)
ARHGAP39 (Vilse) binds ROBO1:SLIT2 (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
ROBO1:SLIT2:ARHGAP39 [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Inactivation of CDC42 (Homo sapiens)
SLIT2:ROBO1:SRGAP [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Inactivation of RAC1 (Homo sapiens)
ROBO1:SLIT2:ARHGAP39 [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SRGAP binds ROBO1:SLIT2 (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:SRGAP [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
ROBO1 binds SLIT2 (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Recruitment of Profilin by Ena/VASP proteins (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP:PFN [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Role of ABL in ROBO-SLIT signaling (Homo sapiens)
Activation of CLASP (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:ABL:CLASP [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Interaction of ABL with ROBO1:SLIT2 (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Phosphorylation of ROBO1 by ABL kinase (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Recruitment of CAP to ABL (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:ABL:CAP [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1 binds CXCR4 (Homo sapiens)
CXCL12:CXCR4:ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1 increases RHOA activity (Homo sapiens)
MYO9B inactivates RHOA (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2-bound ROBO1 binds MYO9B (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
Participants
components
ROBO1 [plasma membrane]
(Homo sapiens)
SLIT2 [extracellular region]
(Homo sapiens)
Participates
as an input of
Interaction of ABL with ROBO1:SLIT2 (Homo sapiens)
SLIT2:ROBO1 binds CXCR4 (Homo sapiens)
SLIT2-bound ROBO1 binds MYO9B (Homo sapiens)
ARHGAP39 (Vilse) binds ROBO1:SLIT2 (Homo sapiens)
NCK binds ROBO1:SLIT2 (Homo sapiens)
SRGAP binds ROBO1:SLIT2 (Homo sapiens)
Ena/VASP proteins bind ROBO1:SLIT2 complex (Homo sapiens)
as a component of
SLIT2:ROBO1:ABL [plasma membrane] (Homo sapiens)
CXCL12:CXCR4:ROBO1:SLIT2 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:NCK [plasma membrane] (Homo sapiens)
ROBO1:SLIT2:ARHGAP39 [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:SRGAP [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
as an output of
ROBO1 binds SLIT2 (Homo sapiens)
Inferred To
ROBO1:SLIT2 [plasma membrane]
(Bos taurus)
ROBO1:SLIT2 [plasma membrane]
(Drosophila melanogaster)
ROBO1:SLIT2 [plasma membrane]
(Mus musculus)
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