Reactome | ROBO1 [plasma membrane]

ROBO1 [plasma membrane]

Stable Identifier

R-HSA-204361

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Roundabout homolog 1, ROB1_HUMAN

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External Reference Information

External Reference

UniProt:Q9Y6N7 ROBO1

Gene Names

ROBO1, DUTT1

Chain

signal peptide:1-25, chain:26-1651

Reference Genes

BioGPS Gene:6091 ROBO1

COSMIC (genes):ROBO1 ROBO1

CTD Gene:6091 ROBO1

dbSNP Gene:6091 ROBO1

ENSEMBL:ENSG00000169855 ROBO1

HGNC:10249 ROBO1

Monarch:6091 ROBO1

NCBI Gene:6091 ROBO1

OMIM:602430 ROBO1

UCSC:Q9Y6N7 ROBO1

Reference Transcript

Other Identifiers

11725495_a_at

11751560_a_at

11758227_s_at

16956386

213194_PM_at

213194_at

2683764

2683765

2683766

2683767

2683768

2683769

2683770

2683771

2683772

2683773

2683774

2683781

2683785

2683786

2683790

2683791

2683792

2683793

2683794

2683795

2683797

2683798

2683799

2683800

2683801

2683802

2683804

2683805

2683806

2683807

2683808

2683813

2683814

2683816

2683817

2683818

2683821

2683850

2683864

2683865

2683866

2683867

2683868

2683869

2683870

2683871

2683877

2683895

2683899

2683900

2683901

2683902

2683903

2683963

2683964

2683993

32944_at

42644_at

55461_at

6091

8088919

85473_at

A_23_P80503

A_24_P77432

GE63242

GO:0002042

GO:0003129

GO:0003148

GO:0003180

GO:0003184

GO:0003272

GO:0005515

GO:0005737

GO:0005886

GO:0006919

GO:0006935

GO:0007155

GO:0007156

GO:0007399

GO:0007411

GO:0008046

GO:0009986

GO:0010628

GO:0010629

GO:0016199

GO:0021836

GO:0030154

GO:0030275

GO:0030336

GO:0030424

GO:0030949

GO:0033116

GO:0033600

GO:0035025

GO:0035385

GO:0035904

GO:0042802

GO:0042995

GO:0043005

GO:0043406

GO:0045747

GO:0048856

GO:0048870

GO:0050772

GO:0050925

GO:0060089

GO:0060412

GO:0070100

GO:1900748

HMNXSV003043301

Hs.301198.0.S2_3p_at

ILMN_1666468

ILMN_1710723

ILMN_1806790

PH_hs_0026807

TC03001570.hg

Participates

as a candidate of

ROBO2,(ROBO1) [plasma membrane] (Homo sapiens)

as a component of

as an output of

as an input of

as a member of

ROBO1,ROBO2 [plasma membrane] (Homo sapiens)

Other forms of this molecule

p-Y1073-ROBO1 [plasma membrane]

PolyUb-ROBO1 [plasma membrane]

Inferred To

Robo1 [plasma membrane] (Mus musculus)

ROBO1 [plasma membrane] (Bos taurus)

robo2 [plasma membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000420637, ENST00000464233, ENST00000467549, ENST00000495273, ENSP00000420321, ENSP00000417992

OpenTargets

ENSG00000169855

HPA

ENSG00000169855-ROBO1

PRO

Q9Y6N7

Pharos - Targets

Q9Y6N7

GlyGen

Q9Y6N7

Orphanet

ROBO1

PDB

5OPE, 5O5I, 6A78, 2V9T, 2EO9, 6A79, 5O5G, 2V9R, 6A77, 3WIH, 4HLJ, 2V9Q

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O94813 SLIT2	3	SLIT2(31-1121) [extracellular region] (R-HSA-426409) SLIT2(1122-1529) [extracellular region] (R-HSA-426412) SLIT2 [extracellular region] (R-HSA-375997)	0.558	2
UniProt:O75044 SRGAP2	1	SRGAP2 [cytosol] (R-HSA-195131)	0.558	3

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