Interaction of ABL with ROBO1:SLIT2

Stable Identifier
R-HSA-376141
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Interaction of ABL with ROBO1:SLIT2
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
ABL (ABL1 or ABL2) binds directly, via its SH3 domain, to the CC3 motif in the cytoplasmic domain of human ROBO1 (Bashaw et al. 2000).
Literature References
PubMed ID Title Journal Year
10892742 Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

Pawson, T, Bashaw, GJ, Goodman, CS, Kidd, T, Murray, D

Cell 2000
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Orthologous Events
Interaction of ABL with ROBO1:SLIT2 (Bos taurus)
Interaction of ABL with ROBO1:SLIT2 (Drosophila melanogaster)
Interaction of ABL with ROBO1:SLIT2 (Mus musculus)
Authored
Garapati, P V  (2008-09-05)
Reviewed
Jaworski, A  (2017-07-31)
Kidd, T  (2009-08-18)
Created
Garapati, P V  (2008-09-05)
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