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3x4Hyp-GalHyl-COL7A1(17-2821)
Stable Identifier
R-HSA-3605686
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
3x4Hyp-GalHyl-COL7A1 -NC2, 4-Hyp 5-Gal-Hyl collagen alpha-1(VII) chain, COL7A1, CO7A1_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Anchoring fibril formation (Homo sapiens)
Cleavage of collagen VII NC2 region by BMP1 (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII binds laminin-322 and collagen IV (Homo sapiens)
Anchoring fibril complex [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Formation of anchoring fibrils (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Hemidesmosome formation (Homo sapiens)
Collagen type VII fibril:Laminin-332 [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Type I hemidesmosome complex [extracellular region] (Homo sapiens)
Collagen type VII fibril:Laminin-332 [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VII degradation by MMP1,2,3 (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
FN1 binds Collagen types I-V, VII (Homo sapiens)
Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
FN1(32-2386):Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen types I-V, VII [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Collagen type VII binds integrin alpha2beta1 (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII fibril:Integrin alpha2beta1 [plasma membrane] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Laminin interactions (Homo sapiens)
Collagen type VII binds collagen type IV (Homo sapiens)
Collagen type IV networks:Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Laminin-332 binds collagen type VII (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
Collagen type VII fibril:Laminin-332 [extracellular region] (Homo sapiens)
Collagen type VII fibril [extracellular region] (Homo sapiens)
Collagen type VII -NC2 hexamer [extracellular region] (Homo sapiens)
Collagen type VII -NC2 trimer [extracellular region] (Homo sapiens)
Collagen alpha-1(VII) -NC2 chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02388 COL7A1
Gene Names
COL7A1
Chain
signal peptide:1-16, chain:17-2944
Reference Genes
BioGPS Gene:1294 COL7A1
COSMIC (genes):COL7A1 COL7A1
CTD Gene:1294 COL7A1
dbSNP Gene:1294 COL7A1
ENSEMBL:ENSG00000114270 COL7A1
HGNC:2214 COL7A1
KEGG Gene (Homo sapiens):hsa:1294 COL7A1
Monarch:1294 COL7A1
NCBI Gene:1294 COL7A1
OMIM:120120 COL7A1
UCSC:Q02388 COL7A1
Reference Transcript
RefSeq:XM_011533337.1 COL7A1
RefSeq:NM_000094.3 COL7A1
Other Identifiers
0005130047
11721705_at
1294
16357
16953458
204136_at
217312_s_at
32123_at
42420
8086985
AAA36357
AAA58965
AAA75438
AAA89196
AAA96439
AAB24637
BAA02853
CAB016357
CCDS2773
COL7A1
COL7A1-201
D13694
ENSG00000114270
ENSP00000332371
ENST00000328333
EntrezGene:1294
g4502960_3p_at
GE57549
GO:0000139
GO:0003674
GO:0004867
GO:0005515
GO:0005575
GO:0005576
GO:0005578
GO:0005581
GO:0005590
GO:0005604
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0006461
GO:0006810
GO:0006888
GO:0007155
GO:0008150
GO:0008544
GO:0009056
GO:0009790
GO:0010466
GO:0010951
GO:0016192
GO:0022607
GO:0030134
GO:0030154
GO:0030198
GO:0030234
GO:0030414
GO:0030574
GO:0031012
GO:0031410
GO:0033116
GO:0035987
GO:0042802
GO:0043226
GO:0043234
GO:0048208
GO:0048646
GO:0048856
GO:0061024
GO:0065003
HGNC:2214
HPA042420
Hs.1640.1.S1_3p_a_at
Hs.476218
ILMN_1751161
IPR002035
IPR002223
IPR003961
IPR008160
IPR013783
IPR020901
L02870
L06862
L23982
LRG_286
LRG_286t1
M65158
M96984
MIM:120120
MIM:131705
MIM:131750
MIM:131850
MIM:132000
MIM:226600
MIM:604129
MIM:607523
NM_000094
NP_000085
PF00014
PF00041
PF00092
PF01391
PH_hs_0000224
PR00453
PR00759
S51236
SM00060
SM00327
TC03001382.hg
uc003ctz.3
UPI0000126D20
XM_011533337
XM_017005688
XM_017005689
XM_017005690
XM_017005691
XM_017005692
XP_011531639
XP_016861177
XP_016861178
XP_016861179
XP_016861180
XP_016861181
XR_001740003
XR_001740004
XR_001740005
XR_001740006
XR_001740007
XR_001740008
Participant Of
hasMember
Collagen alpha-1(VII) -NC2 chains [extracellular region]
Other forms of this molecule
3x4Hyp-3Hyp-5Hyl-COL7A1(2822-2944) [extracellular region]
5Hyl-COL7A1(2822-2944) [extracellular region]
3x4Hyp-3Hyp-COL7A1(2822-2944) [extracellular region]
3x4Hyp-5Hyl-COL7A1(2822-2944) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL7A1(2822-2944) [extracellular region]
COL7A1(2822-2944) [extracellular region]
3x4Hyp-GlcGalHyl-COL7A1(2822-2944) [extracellular region]
3x4Hyp-GalHyl-COL7A1(2822-2944) [extracellular region]
3x4Hyp-COL7A1(2822-2944) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1(2822-2944) [extracellular region]
GlcGalHyl-COL7A1(2822-2944) [extracellular region]
GalHyl-COL7A1(2822-2944) [extracellular region]
COL7A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1 [extracellular region]
GalHyl-COL7A1 [extracellular region]
3x4Hyp-3Hyp-COL7A1 [extracellular region]
3x4Hyp-COL7A1 [extracellular region]
3x4Hyp-5Hyl-COL7A1 [extracellular region]
GlcGalHyl-COL7A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL7A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL7A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL7A1 [extracellular region]
5Hyl-COL7A1 [extracellular region]
3x4Hyp-GalHyl-COL7A1 [extracellular region]
3x4Hyp-GalHyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-GlcGalHyl-COL7A1(17-?) [extracellular region]
3x4Hyp-3Hyp-COL7A1(?-2944) [extracellular region]
3x4Hyp-COL7A1(?-2944) [extracellular region]
GlcGalHyl-COL7A1(17-?) [extracellular region]
3x4Hyp-5Hyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL7A1(17-?) [extracellular region]
GalHyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL7A1(?-2944) [extracellular region]
COL7A1(17-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1(17-?) [extracellular region]
COL7A1(?-2944) [extracellular region]
3x4Hyp-COL7A1(17-?) [extracellular region]
3x4Hyp-3Hyp-COL7A1(17-?) [extracellular region]
GalHyl-COL7A1(17-?) [extracellular region]
GlcGalHyl-COL7A1(?-2944) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL7A1(17-?) [extracellular region]
3x4Hyp-5Hyl-COL7A1(17-?) [extracellular region]
3x4Hyp-GalHyl-COL7A1(17-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL7A1(?-2944) [extracellular region]
5Hyl-COL7A1(?-2944) [extracellular region]
5Hyl-COL7A1(17-?) [extracellular region]
5Hyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-5Hyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-3Hyp-5Hyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GlcGalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-3Hyp-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-GalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-3Hyp-GalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-GlcGalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
5Hyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-5Hyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
GlcGalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-3Hyp-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-GalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-3Hyp-GalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
GalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-GlcGalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
3x4Hyp-3Hyp-5Hyl-COL7A1 [COPII-coated ER to Golgi transport vesicle]
GalHyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-3Hyp-COL7A1(17-2821) [extracellular region]
5Hyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1(17-2821) [extracellular region]
COL7A1(17-2821) [extracellular region]
3x4Hyp-5Hyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-GlcGalHyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-COL7A1(17-2821) [extracellular region]
GlcGalHyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL7A1(17-2821) [extracellular region]
3x4Hyp-3Hyp-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL7A1 [endoplasmic reticulum lumen]
5Hyl-COL7A1 [endoplasmic reticulum lumen]
COL7A1 [endoplasmic reticulum lumen]
GlcGalHyl-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL7A1 [endoplasmic reticulum lumen]
GalHyl-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL7A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL7A1 [endoplasmic reticulum lumen]
Inferred To
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Bos taurus)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Canis familiaris)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Danio rerio)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Gallus gallus)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Mus musculus)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Rattus norvegicus)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Sus scrofa)
3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Taeniopygia guttata)
Homologues of 3x4Hyp-GalHyl-COL7A1(17-2821) [extracellular region] (Danio rerio)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
XP_011531639.1
,
NP_000085.1
GeneCards
Q02388
PRO
Q02388
Orphanet
15781
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5JRA6 MIA3
3
MIA3 [endoplasmic reticulum lumen]
(R-HSA-8956743)
p-MIA3 [endoplasmic reticulum lumen]
(R-HSA-8957064)
MIA3 [endoplasmic reticulum membrane]
(R-HSA-5689472)
0.524
2
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