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AP1B1 [Golgi membrane]
Stable Identifier
R-HSA-350809
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
AP-1 beta subunit
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP1B1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q10567 AP1B1
Gene Names
AP1B1, ADTB1, BAM22, CLAPB2
Chain
chain:1-949
Reference Genes
BioGPS Gene:162 AP1B1
COSMIC (genes):AP1B1 AP1B1
CTD Gene:162 AP1B1
dbSNP Gene:162 AP1B1
ENSEMBL:ENSG00000100280 AP1B1
HGNC:554 AP1B1
KEGG Gene (Homo sapiens):162 AP1B1
Monarch:162 AP1B1
NCBI Gene:162 AP1B1
OMIM:600157 AP1B1
UCSC:Q10567 AP1B1
Reference Transcript
RefSeq:NM_001127.3 AP1B1
RefSeq:NM_001166019.1 AP1B1
RefSeq:NM_145730.2 AP1B1
Other Identifiers
0006860707
11730427_a_at
11730428_a_at
162
16933591
205423_at
3956782
3956783
3956784
3956785
3956788
3956791
3956792
3956793
3956795
3956796
3956798
3956799
3956800
3956801
3956803
3956804
3956805
3956807
3956808
3956810
3956811
3956812
3956814
3956815
3956816
3956817
3956823
3956824
3956829
3956831
40745_at
8075217
A_23_P6398
A_33_P3317593
GE57637
GO:0000139
GO:0001822
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005794
GO:0005829
GO:0006810
GO:0006886
GO:0007368
GO:0007507
GO:0008150
GO:0015031
GO:0016020
GO:0016192
GO:0019886
GO:0019899
GO:0019901
GO:0030117
GO:0030131
GO:0030276
GO:0030659
GO:0030665
GO:0031410
GO:0032588
GO:0032991
GO:0043226
GO:0043231
GO:0044403
GO:0048856
GO:0050690
ILMN_1781983
ILMN_2387505
L13939_s_at
PH_hs_0016268
TC22000634.hg
g4501972_3p_at
Participant Of
hasComponent
AP-1 Complex [Golgi membrane]
Other forms of this molecule
AP1B1 [cytosol]
AP1B1 [trans-Golgi network membrane]
AP1B1 [lysosomal membrane]
AP1B1 [cytoplasmic vesicle membrane]
Inferred To
Ap1b1 [Golgi membrane] (Mus musculus)
Ap1b1 [Golgi membrane] (Rattus norvegicus)
APL2 [Golgi membrane] (Saccharomyces cerevisiae)
AP-1-2beta [Golgi membrane] (Drosophila melanogaster)
apl2 [Golgi membrane] (Schizosaccharomyces pombe)
ap1b1 [Golgi membrane] (Danio rerio)
ap1b1 [Golgi membrane] (Dictyostelium discoideum)
AP1B1 [Golgi membrane] (Canis familiaris)
AP1B1 [Golgi membrane] (Gallus gallus)
AP1B1 [Golgi membrane] (Plasmodium falciparum)
AP1B1 [Golgi membrane] (Sus scrofa)
AP1B1 [Golgi membrane] (Xenopus tropicalis)
apb-1 [Golgi membrane] (Caenorhabditis elegans)
Cross References
RefSeq
NP_001159491.1
,
NP_663782.2
,
NP_001118.3
OpenTargets
ENSG00000100280
HPA
ENSG00000100280-AP1B1
GeneCards
Q10567
Ensembl
ENST00000357586
,
ENSG00000100280
,
ENSP00000386071
,
ENST00000402502
,
ENSP00000319361
,
ENSP00000400065
,
ENST00000415447
,
ENST00000405198
,
ENST00000432560
,
ENSP00000387612
,
ENSP00000384194
,
ENST00000317368
,
ENSP00000350199
PRO
Q10567
Orphanet
28822
PDB
4HMY
,
6DFF
,
6D83
,
4P6Z
,
6CM9
,
6CRI
,
6D84
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]
6
PI(4,5)P2 [Golgi membrane]
(R-ALL-1806165)
PI(4,5)P2 [plasma membrane]
(R-ALL-179856)
PI(4,5)P2 [endoplasmic reticulum membrane]
(R-ALL-2023856)
PI(4,5)P2 [nucleoplasm]
(R-ALL-6810412)
PI(4,5)P2 [cytoplasmic vesicle membrane]
(R-ALL-8874467)
PI(4,5)P2 [early endosome membrane]
(R-ALL-8849966)
0.462
2
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate [ChEBI:16618]
6
PI(3,4,5)P3 [endocytic vesicle membrane]
(R-ALL-917725)
PIP3 [plasma membrane]
(R-ALL-38117)
PI(3,4,5)P3 [endosome membrane]
(R-ALL-917716)
PI(3,4,5)P3 [early endosome membrane]
(R-ALL-8849955)
PI(3,4,5)P3 [cytoplasmic vesicle membrane]
(R-ALL-8874468)
PI(3,4,5)P3 [plasma membrane]
(R-ALL-179838)
0.462
2
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