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AP1B1 [cytosol]
Stable Identifier
R-HSA-167705
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
AP-1 beta subunit
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
HIV Infection (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
The role of Nef in HIV-1 replication and disease pathogenesis (Homo sapiens)
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters (Homo sapiens)
Nef mediated downregulation of MHC class I complex cell surface expression (Homo sapiens)
Degradation of MHC I Complex (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Nef:class I MHC complex:AP-1:PACS-1 Complex [early endosome membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Formation of MHC I:Nef:AP-1:PACS-1 Complex (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Nef:class I MHC complex:Ap-1:PACS-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Transport of MHC I:Nef:AP-1:PACS-1 Complex (Homo sapiens)
Nef:class I MHC complex:AP-1:PACS-1 Complex [early endosome membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Nef:class I MHC complex:Ap-1:PACS-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
TGN-lysosomal vesicle coat assembly (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
trans-Golgi Network Derived Vesicle Uncoating (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Homo sapiens)
AP-1 Complex [cytosol] (Homo sapiens)
AP1B1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q10567 AP1B1
Gene Names
AP1B1, ADTB1, BAM22, CLAPB2
Chain
chain:1-949
Reference Genes
BioGPS Gene:162 AP1B1
COSMIC (genes):AP1B1 AP1B1
CTD Gene:162 AP1B1
dbSNP Gene:162 AP1B1
ENSEMBL:ENSG00000100280 AP1B1
HGNC:554 AP1B1
KEGG Gene (Homo sapiens):162 AP1B1
Monarch:162 AP1B1
NCBI Gene:162 AP1B1
OMIM:600157 AP1B1
UCSC:Q10567 AP1B1
Reference Transcript
RefSeq:NM_145730.2 AP1B1
RefSeq:NM_001127.3 AP1B1
RefSeq:NM_001166019.1 AP1B1
Other Identifiers
0006860707
11730427_a_at
11730428_a_at
162
16933591
205423_at
3956782
3956783
3956784
3956785
3956788
3956791
3956792
3956793
3956795
3956796
3956798
3956799
3956800
3956801
3956803
3956804
3956805
3956807
3956808
3956810
3956811
3956812
3956814
3956815
3956816
3956817
3956823
3956824
3956829
3956831
40745_at
8075217
A_23_P6398
A_33_P3317593
GE57637
GO:0000139
GO:0001822
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005794
GO:0005829
GO:0006810
GO:0006886
GO:0006892
GO:0007368
GO:0007507
GO:0008150
GO:0015031
GO:0016020
GO:0016192
GO:0019886
GO:0019899
GO:0019901
GO:0030117
GO:0030131
GO:0030276
GO:0030659
GO:0030665
GO:0031410
GO:0032588
GO:0032991
GO:0043226
GO:0043231
GO:0044403
GO:0048856
GO:0050690
HMNXSV003020318
ILMN_1781983
ILMN_2387505
L13939_s_at
PH_hs_0016268
TC22000634.hg
g4501972_3p_at
Participates
as a component of
AP-1 Complex [cytosol] (Homo sapiens)
Other forms of this molecule
AP1B1 [cytoplasmic vesicle membrane]
AP1B1 [Golgi membrane]
AP1B1 [lysosomal membrane]
AP1B1 [trans-Golgi network membrane]
Inferred To
apb-1 [cytosol]
(Caenorhabditis elegans)
AP1B1 [cytosol]
(Bos taurus)
AP1B1 [cytosol]
(Canis familiaris)
AP1B1 [cytosol]
(Gallus gallus)
AP1B1 [cytosol]
(Plasmodium falciparum)
AP1B1 [cytosol]
(Sus scrofa)
Ghost homologue of AP1B1 [cytosol]
(Xenopus tropicalis)
APL2 [cytosol]
(Saccharomyces cerevisiae)
AP-1-2beta [cytosol]
(Drosophila melanogaster)
ap1b1 [cytosol]
(Danio rerio)
ap1b1 [cytosol]
(Dictyostelium discoideum)
apl2 [cytosol]
(Schizosaccharomyces pombe)
Ap1b1 [cytosol]
(Mus musculus)
Ap1b1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_001118.3
,
NP_001159491.1
,
NP_663782.2
OpenTargets
ENSG00000100280
GeneCards
Q10567
HPA
ENSG00000100280-AP1B1
Ensembl
ENSP00000319361
,
ENST00000317368
,
ENSP00000384194
,
ENST00000405198
,
ENST00000357586
,
ENSG00000100280
,
ENSP00000350199
,
ENST00000432560
,
ENSP00000400065
PRO
Q10567
Pharos - Targets
Q10567
GlyGen
Q10567
Orphanet
28822
PDB
6DFF
,
6CRI
,
6D84
,
4P6Z
,
6D83
,
4HMY
,
6CM9
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