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TLE3 [nucleoplasm]
Stable Identifier
R-HSA-3322363
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser for interactor UniProt:Q08117 TLE5
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)
TLE3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q04726 TLE3
Gene Names
TLE3, KIAA1547
Chain
chain:1-772
Reference Genes
BioGPS Gene:7090 TLE3
COSMIC - genes:TLE3 TLE3
CTD Gene:7090 TLE3
dbSNP Gene:7090 TLE3
ENSEMBL:ENSG00000140332 TLE3
HGNC:11839 TLE3
KEGG:hsa:7090 TLE3
Monarch:7090 TLE3
NCBI Gene:7090 TLE3
OMIM:600190 TLE3
UCSC:Q04726 TLE3
Reference Transcript
RefSeq:NM_001282979.2 TLE3
RefSeq:NM_001282982.1 TLE3
RefSeq:NM_020908.3 TLE3
RefSeq:NM_001282981.2 TLE3
RefSeq:NM_005078.4 TLE3
RefSeq:NM_001105192.3 TLE3
RefSeq:NM_001282980.2 TLE3
Participates
as a component of
ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm] (Homo sapiens)
TLE3 tetramer [nucleoplasm] (Homo sapiens)
as an input of
ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)
as a member of
TLE [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-TLE3 [nucleoplasm]
Inferred To
TLE3 [nucleoplasm]
(Bos taurus)
TLE3 [nucleoplasm]
(Canis familiaris)
TLE3 [nucleoplasm]
(Gallus gallus)
TLE3 [nucleoplasm]
(Sus scrofa)
gro [nucleoplasm]
(Drosophila melanogaster)
unc-37 [nucleoplasm]
(Caenorhabditis elegans)
tle3b [nucleoplasm]
(Danio rerio)
Tle3 [nucleoplasm]
(Mus musculus)
Tle3 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001098662.1
,
NP_001269909.1
,
NP_001269910.1
,
NP_001269911.1
,
NP_005069.2
,
NP_065959.1
,
NP_001269908.1
OpenTargets
ENSG00000140332
ENSEMBL
ENSP00000394717
,
ENST00000440567
,
ENST00000557907
,
ENSP00000415057
,
ENSP00000453435
,
ENST00000317509
,
ENSP00000453107
,
ENST00000557997
,
ENST00000559048
,
ENST00000558379
,
ENST00000451782
,
ENSG00000140332
,
ENSP00000319233
,
ENSP00000453760
,
ENSP00000452871
,
ENSP00000453083
,
ENST00000558939
HPA
ENSG00000140332-TLE3
GeneCards
TLE3
PRO
Q04726
Pharos - Targets
Q04726
GlyGen
Q04726
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04725 TLE2
2
Ub-TLE2 [nucleoplasm]
(R-HSA-3322370)
TLE2 [nucleoplasm]
(R-HSA-212354)
0.643
4
UniProt:Q9C009 FOXQ1
1
FOXQ1 [nucleoplasm]
(R-HSA-9931149)
0.569
4
UniProt:Q05925 HME1
0.569
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.564
2
UniProt:O95231 VENTX
1
VENTX [nucleoplasm]
(R-HSA-8853887)
0.527
2
UniProt:Q04724 TLE1
2
Ub-TLE1 [nucleoplasm]
(R-HSA-3322369)
TLE1 [nucleoplasm]
(R-HSA-212327)
0.527
4
UniProt:P0DTD1-PRO_0000449630 REP
0.527
2
UniProt:P55083 MFAP4
1
MFAP4 [extracellular region]
(R-HSA-2161384)
0.527
5
UniProt:Q12952 FOXL1
0.483
2
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