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Ub-TLE3 [nucleoplasm]
Stable Identifier
R-HSA-3322374
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
ub-TLE3
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Deactivation of the beta-catenin transactivating complex (Homo sapiens)
XIAP dissociates from ub-TLE (Homo sapiens)
ub-TLE [nucleoplasm] (Homo sapiens)
ub-TLE3 tetramer [nucleoplasm] (Homo sapiens)
Ub-TLE3 [nucleoplasm] (Homo sapiens)
ub-TLE:XIAP [nucleoplasm] (Homo sapiens)
ub-TLE [nucleoplasm] (Homo sapiens)
ub-TLE3 tetramer [nucleoplasm] (Homo sapiens)
Ub-TLE3 [nucleoplasm] (Homo sapiens)
XIAP monoubiquinates TLE (Homo sapiens)
ub-TLE:XIAP [nucleoplasm] (Homo sapiens)
ub-TLE [nucleoplasm] (Homo sapiens)
ub-TLE3 tetramer [nucleoplasm] (Homo sapiens)
Ub-TLE3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q04726 TLE3
Gene Names
TLE3, KIAA1547
Chain
chain:1-772
Reference Genes
BioGPS Gene:7090 TLE3
COSMIC (genes):TLE3 TLE3
CTD Gene:7090 TLE3
dbSNP Gene:7090 TLE3
ENSEMBL:ENSG00000140332 TLE3
HGNC:11839 TLE3
KEGG:hsa:7090 TLE3
Monarch:7090 TLE3
NCBI Gene:7090 TLE3
OMIM:600190 TLE3
UCSC:Q04726 TLE3
Reference Transcript
RefSeq:NM_020908.2 TLE3
RefSeq:NM_001282980.1 TLE3
RefSeq:NM_001282981.1 TLE3
RefSeq:NM_001282979.1 TLE3
RefSeq:NM_001105192.2 TLE3
RefSeq:NM_001282982.1 TLE3
RefSeq:NM_005078.3 TLE3
Participates
as a component of
ub-TLE3 tetramer [nucleoplasm] (Homo sapiens)
Other forms of this molecule
TLE3 [nucleoplasm]
Inferred To
TLE3 [nucleoplasm]
(Bos taurus)
TLE3 [nucleoplasm]
(Canis familiaris)
TLE3 [nucleoplasm]
(Gallus gallus)
TLE3 [nucleoplasm]
(Sus scrofa)
gro [nucleoplasm]
(Drosophila melanogaster)
tle3b [nucleoplasm]
(Danio rerio)
Tle3 [nucleoplasm]
(Mus musculus)
Tle3 [nucleoplasm]
(Rattus norvegicus)
Modified Residues
Name
ubiquitinylated lysine at unknown position
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
OpenTargets
ENSG00000140332
ENSEMBL
ENSG00000140332
,
ENSP00000453435
,
ENST00000557997
,
ENST00000451782
,
ENST00000558379
,
ENSP00000453107
,
ENSP00000453760
,
ENSP00000394717
,
ENSP00000452871
,
ENST00000559048
,
ENST00000440567
,
ENST00000557907
,
ENSP00000453083
,
ENSP00000415057
,
ENSP00000319233
,
ENST00000558939
,
ENST00000317509
HPA
ENSG00000140332-TLE3
GeneCards
TLE3
PRO
Q04726
Pharos - Targets
Q04726
GlyGen
Q04726
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q05925 HME1
0.569
3
UniProt:Q9C009 FOXQ1
0.569
4
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.564
2
UniProt:P0DTD1-PRO_0000449630 REP
0.527
2
UniProt:Q04725 TLE2
2
Ub-TLE2 [nucleoplasm]
(R-HSA-3322370)
TLE2 [nucleoplasm]
(R-HSA-212354)
0.527
3
UniProt:Q12952 FOXL1
0.483
2
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