Reactome | VRK2-2 [nucleoplasm]

VRK2-2 [nucleoplasm]

Stable Identifier

R-HSA-2993893

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

VRK2B

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q86Y07-2 VRK2

Gene Names

VRK2

Participates

as a candidate of

VRK1/VRK2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

VRK2-2 [cytosol]

Inferred To

VRK2 [nucleoplasm] (Bos taurus)

VRK2 [nucleoplasm] (Canis familiaris)

VRK2 [nucleoplasm] (Sus scrofa)

Vrk2 [nucleoplasm] (Rattus norvegicus)

VRK2-2 [nucleoplasm] (Mus musculus)

Cross References

RefSeq

NP_001275768.1, XP_047301704.1, XP_047301703.1, XP_047301701.1, NP_001275767.1, NP_001275766.1, NP_001123953.1, NP_001275765.1, NP_001123954.1, NP_001123955.1, NP_001123952.1, XP_006712154.1, XP_006712153.1, XP_005264597.1, XP_011531394.1, NP_006287.2

ZINC - World Drugs

VRK2_HUMAN

Guide to Pharmacology - Targets

2276

OpenTargets

ENSG00000028116

ENSEMBL

ENST00000417641, ENST00000412104, ENST00000648897, ENST00000340157, ENSP00000402375, ENST00000440705, ENSP00000408002, ENSP00000404156, ENSP00000342381, ENSP00000398323, ENSG00000028116, ENSP00000497378, ENST00000435505

ZINC - FDA approved

VRK2_HUMAN

ZINC - Substances

VRK2_HUMAN

ZINC target

Q86Y07

PRO

Q86Y07

PDB

8Q1Z, 6NCG, 5UU1, 9FET, 2V62

ZINC - Investigational

VRK2_HUMAN

HPA

ENSG00000028116-VRK2

GeneCards

VRK2

Pharos - Targets

Q86Y07

ZINC - Predictions - Purchasable

VRK2_HUMAN

HMDB Protein

HMDBP01323

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N4V1 MMGT1	1	MMGT1 [Golgi membrane] (R-HSA-5216137)	0.556	3
UniProt:Q02750 MAP2K1	20	MAP2K1(9-393) [cytosol] (R-HSA-5211353) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1 F53S [cytosol] (R-HSA-9652034) MAP2K1 D67N [cytosol] (R-HSA-9652016) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837) MAP2K1 [cytosol] (R-HSA-59502) p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-HSA-112339) p-T286,T292-MAP2K1 [cytosol] (R-HSA-112374) p-S,218, S222,T292 MAP2K1 [cytosol] (R-HSA-5674490) MAP2K1 F53C [cytosol] (R-HSA-9652028) MAP2K1 P124Q [cytosol] (R-HSA-9652058) MAP2K1 L42_K57del [cytosol] (R-HSA-9652026) MAP2K1 F53Y [cytosol] (R-HSA-9652041) MAP2K1 P124L [cytosol] (R-HSA-9652056) MAP2K1 G128D [cytosol] (R-HSA-9652043) MAP2K1 D67Y [cytosol] (R-HSA-9652019) MAP2K1 F53V [cytosol] (R-HSA-9652038) MAP2K1 K57T [cytosol] (R-HSA-9652052) MAP2K1 K57N [cytosol] (R-HSA-9652050) MAP2K1 F53L [cytosol] (R-HSA-9652031)	0.524	2
UniProt:P27824 CANX	3	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum membrane] (R-HSA-9932989)	0.483	3

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