MAP2K1

Stable Identifier
R-HSA-59502
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
MEK1, Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1), Dual specificity mitogen-activated protein kinase kinase 1 , MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
MAP2K1, MEK1, PRKMK1
Chain
chain:1-393
Other Identifiers
0001740347
1130_at
11717291_a_at
11749555_a_at
11757478_s_at
16802190
1844_s_at
1S9J
202670_at
26430
2P55
3092255
3092256
3092263
3092264
3598663
3598664
3598670
3598671
3598672
3598673
3598688
3598690
3598691
3598692
3598696
3598697
3598700
3598701
3598702
3834
3DV3
3DY7
3E8N
3EQB
3EQC
3EQD
3EQF
3EQG
3EQH
3EQI
3MBL
3ORN
3OS3
3PP1
3SLS
3V01
3V04
3VVH
3W8Q
3WIG
3ZLS
3ZLW
3ZLX
3ZLY
3ZM4
4AN2
4AN3
4AN9
4ANB
4ARK
4LMN
4MNE
4U7Z
4U80
4U81
5604
5BX0
5EYM
5HZE
7984319
A4QPA9
A_23_P20248
AAA36318
AAI37460
AAI39730
AK291500
BAF84189
BC137459
BC139729
CAB003834
CCDS10216
CH471082
EAW77765
ENSG00000169032
ENSP00000302486
ENST00000307102
EntrezGene:5604
GE57608
GO:0000003
GO:0000165
GO:0000166
GO:0000187
GO:0000278
GO:0000902
GO:0001932
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004708
GO:0004712
GO:0004713
GO:0004871
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005739
GO:0005768
GO:0005769
GO:0005770
GO:0005783
GO:0005794
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005925
GO:0006412
GO:0006464
GO:0006468
GO:0006810
GO:0006935
GO:0006950
GO:0007049
GO:0007050
GO:0007165
GO:0007346
GO:0007507
GO:0007568
GO:0008022
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009058
GO:0009790
GO:0010628
GO:0010629
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018107
GO:0018108
GO:0021697
GO:0030154
GO:0030182
GO:0030216
GO:0030234
GO:0030878
GO:0031410
GO:0032872
GO:0034641
GO:0040011
GO:0042981
GO:0043167
GO:0043226
GO:0043539
GO:0045597
GO:0045893
GO:0047485
GO:0048538
GO:0048646
GO:0048679
GO:0048856
GO:0048870
GO:0050772
GO:0060020
GO:0060324
GO:0060425
GO:0060440
GO:0060502
GO:0060674
GO:0060711
GO:0070371
GO:0070374
GO:0071902
GO:0090170
GO:0090398
GO:0097110
GO:1903800
GO:2000641
H3BRW9
HGNC:6840
HPA026430
Hs.3446.0.A2_3p_at
ILMN_1694240
IPR000719
IPR008271
IPR011009
IPR017441
L05624
L05624_s_at
L11284
L11284_at
LRG_725
LRG_725t1
MAP2K1
MAP2K1-201
MIM:163950
MIM:176872
MIM:615279
NM_002755
NP_002746
PF00069
PH_hs_0022483
SM00220
TC15000613.hg
uc010bhq.4
UPI000013EBC9
XM_011521783
XM_017022411
XM_017022412
XP_011520085
XP_016877900
XP_016877901
Participant Of
Other forms of this molecule
Inferred To
Cross References
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Metabolites
GeneCards
BRENDA (Homo sapiens)
Orphanet
ZINC - Predictions - Purchasable
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P15056 BRAF  34 0.976 58
 UniProt:P04049 RAF1  11 0.952 35
 UniProt:P10398 ARAF  4 0.69 5
 UniProt:Q8IVT5 KSR1  5 0.643 7
 UniProt:P28482 MAPK1  7 0.609 2
 UniProt:Q8N9N5 BANP  1 0.556 3
 UniProt:Q9Y297 BTRC  2 0.556 3
 UniProt:P46937 YAP1  7 0.556 3
 UniProt:P31946 YWHAB  1 0.527 2
 UniProt:Q86Y07 VRK2      0.524 2
 UniProt:Q61097  5 0.508 2
 UniProt:Q13526 PIN1  1 0.508 5
 UniProt:Q86Y07-1 VRK2      0.499 2
 UniProt:P27361 MAPK3  4 0.499 2
 UniProt:Q8WWU5-7 TCP11      0.488 2
 UniProt:Q8N9N5-2 BANP      0.488 2
 UniProt:Q9H8W4 PKHF2      0.488 2
 UniProt:Q49A26-4 GLYR1      0.488 2
 UniProt:Q96S96 PEBP4      0.462 3
 UniProt:O75832 PSMD10  2 0.462 2