Reactome | MMGT1 [Golgi membrane]

MMGT1 [Golgi membrane]

Stable Identifier

R-HSA-5216137

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Membrane magnesium transporter 1, MMGT1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N4V1 MMGT1

Gene Names

MMGT1, EMC5, TMEM32

Chain

chain:1-131

Reference Genes

BioGPS Gene:93380 MMGT1

COSMIC (genes):MMGT1 MMGT1

CTD Gene:93380 MMGT1

dbSNP Gene:93380 MMGT1

ENSEMBL:ENSG00000169446 MMGT1

HGNC:28100 MMGT1

KEGG:hsa:93380 MMGT1

Monarch:93380 MMGT1

NCBI Gene:93380 MMGT1

OMIM:301098 MMGT1

UCSC:Q8N4V1 MMGT1

Reference Transcript

Other Identifiers

11719088_at

11749362_a_at

17114478

225125_PM_at

225125_at

4023271

4023273

4023275

4023276

4023277

4023278

4023279

4023280

4023282

4023283

48122_at

8175360

90518_at

93380

A_23_P11224

GE56834

GE631666

GO:0000139

GO:0005215

GO:0005515

GO:0005737

GO:0005768

GO:0005769

GO:0005783

GO:0005789

GO:0005794

GO:0005886

GO:0006812

GO:0006824

GO:0006825

GO:0006826

GO:0015087

GO:0015093

GO:0015095

GO:0015693

GO:0016020

GO:0022890

GO:0031410

GO:0031901

GO:0032977

GO:0034755

GO:0043226

GO:0043231

GO:0045050

GO:0055085

GO:0071816

GO:0072546

GO:0140104

GO:1903830

HMNXSV003038195

Hs.110702.0.A1_3p_at

ILMN_1776216

PH_hs_0006092

TC0X001412.hg

Cross References

OpenTargets

ENSG00000169446

ENSEMBL

ENST00000305963, ENSP00000505226, ENSP00000306220, ENST00000679621

HPA

ENSG00000169446-MMGT1

PRO

Q8N4V1

Pharos - Targets

Q8N4V1

PDB

7ADO, 8S9S, 8EOI, 6Z3W, 7ADP, 6WW7, 8J0O, 8J0N

Interactors (61)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15006 EMC2			0.864	13
UniProt:Q9BV81 EMC6			0.806	8
UniProt:Q9NPA0 EMC7			0.788	11
UniProt:O43402 EMC8			0.725	8
UniProt:Q9P0I2 EMC3	1	EMC3 [endoplasmic reticulum membrane] (R-HSA-9714347)	0.725	7
UniProt:Q5J8M3 EMC4			0.725	6
UniProt:Q5UCC4 EMC10			0.71	6
UniProt:O95167 NDUFA3	1	NDUFA3 [mitochondrial inner membrane] (R-HSA-60180)	0.666	4
UniProt:Q8N766 EMC1			0.643	7
UniProt:Q9Y3B6 EMC9			0.643	5
UniProt:Q9NZ01 TECR	1	TECR [endoplasmic reticulum membrane] (R-HSA-548663)	0.556	3
UniProt:Q969S0 SLC35B4	1	SLC35B4 [Golgi membrane] (R-HSA-742365)	0.556	3
UniProt:Q9H2L4 TMM60			0.556	3
UniProt:Q86Y07 VRK2	2	VRK2 [mitochondrial outer membrane] (R-HSA-9715102) VRK2 [endoplasmic reticulum membrane] (R-HSA-9714457)	0.556	3
UniProt:Q8WVX3-2 C4ORF3			0.556	3
UniProt:Q5J8X5 M4A13			0.556	3
UniProt:Q96ES6 MFSD3			0.556	3
UniProt:Q86Y82 STX12			0.556	3
UniProt:P07204 THBD	1	THBD [plasma membrane] (R-HSA-141030)	0.556	3
UniProt:P55061 BI1			0.556	3
UniProt:Q9H0Q3 FXYD6	1	FXYD6 [plasma membrane] (R-HSA-2752104)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:Q6N075 MFSD5			0.556	3
UniProt:Q6ICL7 S35E4			0.556	3
UniProt:Q9Y3D6 FIS1	2	FIS1 [peroxisomal membrane] (R-HSA-9033123) FIS1 [cytosol] (R-HSA-9033099)	0.556	3
UniProt:Q9UIQ6-2 LNPEP			0.556	3
UniProt:O43752 STX6	2	STX6 [trans-Golgi network membrane] (R-HSA-6811007) STX6 [Golgi membrane] (R-HSA-6811004)	0.556	3
UniProt:P01031 C5	7	C5a [extracellular region] (R-HSA-173677) C5 beta chain [extracellular region] (R-HSA-173675) C5 alpha chain [extracellular region] (R-HSA-173673) C5b alpha' [extracellular region] (R-HSA-173672) C5a-desArg [extracellular region] (R-HSA-8852798) C5aT [extracellular region] (R-HSA-8852711) C5(965-1676) [extracellular region] (R-HSA-8852713)	0.556	3
UniProt:Q9Y5Y5 PEX16	2	PEX16 [peroxisomal membrane] (R-HSA-9603805) PEX16 [cytosol] (R-HSA-9603790)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:Q9NZG7 NINJ2			0.556	3
UniProt:Q86W74-2 ANKRD46			0.556	3
UniProt:Q9NVC3 S38A7			0.556	3
UniProt:Q8NBD8 T229B			0.556	3
UniProt:P07357 C8A	1	C8A [extracellular region] (R-HSA-173716)	0.556	3
UniProt:Q14416 GRM2	1	GRM2 [plasma membrane] (R-HSA-420468)	0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:Q9H1M4 DEFB127	3	DEFB127(?-63) [extracellular region] (R-HSA-1471317) DEFB127(?-63) [Golgi lumen] (R-HSA-975809) DEFB127(1-63) [Golgi lumen] (R-HSA-1470031)	0.556	3
UniProt:Q96GQ5 RUSF1			0.556	3
UniProt:Q9P0S9 TM14C			0.556	3
UniProt:Q6PL24 TMED8			0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:P59542 TAS2R19	1	TAS2R19 [plasma membrane] (R-HSA-3299625)	0.556	3
UniProt:Q9UHX3 ADGRE2	1	EMR2 [plasma membrane] (R-HSA-444760)	0.556	3
UniProt:P61266 STX1B	3	STX1B(1-?) [cytosol] (R-HSA-5246520) STX1B(?-288) [plasma membrane] (R-HSA-5246519) STX1B [plasma membrane] (R-HSA-181479)	0.556	3
UniProt:Q8TBB6 S7A14			0.556	3
UniProt:Q9Y5U4 INSIG2	1	INSIG2 [endoplasmic reticulum membrane] (R-HSA-1655736)	0.556	3
UniProt:Q9GZY8-5 MFF			0.556	3
UniProt:Q9Y6G1 TM14A			0.556	3
UniProt:Q8TBM7 TM254			0.556	3
UniProt:P11215 ITGAM	3	ITGAM [plasma membrane] (R-HSA-202757) ITGAM [specific granule membrane] (R-HSA-6799647) ITGAM [tertiary granule membrane] (R-HSA-6800979)	0.556	3
UniProt:Q8TD06 AGR3			0.556	3
UniProt:Q53FV1 ORMDL2	1	ORMDL2 [endoplasmic reticulum membrane] (R-HSA-8865591)	0.556	3
UniProt:O00155 GPR25	1	GPR25 [plasma membrane] (R-HSA-6805220)	0.556	3
UniProt:Q8IY26 PLPP6	1	PLPP6 [plasma membrane] (R-HSA-8952144)	0.556	3
UniProt:Q69YG0 TMM42			0.556	3
UniProt:P50402 EMD	4	EMD [nuclear envelope] (R-HSA-201573) EMD [cytosol] (R-HSA-9613988) EMD [endoplasmic reticulum membrane] (R-HSA-9613998) EMD [endosome membrane] (R-HSA-9715092)	0.556	3
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.483	3

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