Reactome | TRAPPC4 [plasma membrane]

TRAPPC4 [plasma membrane]

Stable Identifier

R-HSA-2682314

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Trafficking protein particle complex subunit 4, TPPC4_HUMAN, Synbindin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y296 TRAPPC4

Gene Names

TRAPPC4, SBDN, CGI-104, HSPC172, PTD009

Chain

chain:1-219

Reference Genes

BioGPS Gene:51399 TRAPPC4

COSMIC (genes):TRAPPC4 TRAPPC4

CTD Gene:51399 TRAPPC4

dbSNP Gene:51399 TRAPPC4

ENSEMBL:ENSG00000196655 TRAPPC4

ENSEMBL:ENSG00000196655.12 TRAPPC4

ENSEMBL:ENSG00000280495.5 TRAPPC4

HGNC:19943 TRAPPC4

KEGG Gene (Homo sapiens):51399 TRAPPC4

Monarch:51399 TRAPPC4

NCBI Gene:51399 TRAPPC4

OMIM:610971 TRAPPC4

UCSC:Q9Y296 TRAPPC4

Reference Transcript

Other Identifiers

11749400_a_at

16732088

217958_PM_at

217958_at

217959_PM_s_at

217959_s_at

3351777

3351778

3351779

3351782

3351784

3351788

3351789

3351790

3351793

51399

7894041

7944375

91724_at

A_14_P122802

A_14_P134701

A_23_P127613

GE82084

GO:0000139

GO:0005515

GO:0005737

GO:0005768

GO:0005783

GO:0005794

GO:0005795

GO:0005829

GO:0005886

GO:0006888

GO:0006901

GO:0006914

GO:0008021

GO:0016020

GO:0016192

GO:0016358

GO:0030008

GO:0030154

GO:0030425

GO:0031410

GO:0043226

GO:0045202

GO:0045211

GO:0048208

GO:0048856

GO:0061024

GO:0065003

GO:0099022

GO:1990071

GO:1990072

HMNXSV003046509

ILMN_1814650

PH_hs_0014423

g7706666_3p_at

Participates

as a component of

Syndecan-2:TRAPPC4 [plasma membrane] (Homo sapiens)

as an input of

Syndecan-2 binds TRAPPC4 (Homo sapiens)

Other forms of this molecule

TRAPPC4 [cytosol]

Cross References

RefSeq

NP_001305417.1, NP_001305419.1, NP_001305423.1, NP_001305415.1, NP_001305418.1, NP_001305421.1, NP_057230.1

OpenTargets

ENSG00000196655

HPA

ENSG00000196655-TRAPPC4

GeneCards

Q9Y296

Ensembl

ENST00000533632, ENSG00000196655, ENSP00000436005, ENSP00000486496, ENST00000629713, ENSG00000280495, ENSP00000487467, ENST00000629243, ENSP00000405033, ENST00000434101

PRO

Q9Y296

Pharos - Targets

Q9Y296

Orphanet

29244

PDB

2ZMV, 2JSN, 2J3T

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96QF0 RAB3IP	1	RAB3IP [cytosol] (R-HSA-5617610)	0.735	5
UniProt:P28482 MAPK1	18	MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293) MAPK1 [azurophil granule lumen] (R-HSA-6799225) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185-MAPK1 [cytosol] (R-HSA-9635773) MAPK1 [nucleoplasm] (R-HSA-199960) MAPK1 [cytosol] (R-HSA-59282) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354)	0.581	3
UniProt:O75865 TRAPPC6A	1	TRAPPC6A [cytosol] (R-HSA-5685733)	0.544	2
UniProt:Q9BZR8 BCL2L14	1	BCL2L14 [cytosol] (R-HSA-6791317)	0.527	2
UniProt:Q9Y5R8 TRAPPC1	3	TRAPPC1 [extracellular region] (R-HSA-6806180) TRAPPC1 [azurophil granule lumen] (R-HSA-6799360) TRAPPC1 [cytosol] (R-HSA-5683750)	0.508	2

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