Reactome | BCL2L14 [cytosol]

BCL2L14 [cytosol]

Stable Identifier

R-HSA-6791317

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Apoptosis facilitator Bcl-2-like protein 14, BCLG

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)
        
        TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain (Homo sapiens)
        
        TP53 stimulates BCL2L14 gene expression (Homo sapiens)
        
        BCL2L14 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BZR8 BCL2L14

Gene Names

BCL2L14, BCLG

Chain

chain:1-327

Reference Genes

BioGPS Gene:79370 BCL2L14

COSMIC (genes):BCL2L14 BCL2L14

CTD Gene:79370 BCL2L14

dbSNP Gene:79370 BCL2L14

ENSEMBL:ENSG00000121380 BCL2L14

HGNC:16657 BCL2L14

KEGG:hsa:79370 BCL2L14

Monarch:79370 BCL2L14

NCBI Gene:79370 BCL2L14

OMIM:606126 BCL2L14

UCSC:Q9BZR8 BCL2L14

Reference Transcript

Other Identifiers

11738850_a_at

11740374_a_at

11759226_at

1552841_PM_s_at

1552841_s_at

1569719_PM_at

1569719_at

221241_PM_s_at

221241_s_at

3405208

3405209

3405210

3405211

3405212

3405215

3405216

3405217

3405221

3405223

3405225

3405226

3405227

3405228

3405232

3405233

3405234

3405244

3405247

3405248

3405249

42131_at

50827_at

67547_at

79370

7953993

A_14_P127897

A_23_P116653

A_23_P128050

GE83170

GO:0005515

GO:0005737

GO:0005829

GO:0006915

GO:0012501

GO:0012505

GO:0016020

GO:0019901

GO:0042981

GO:0043226

GO:0043229

GO:2001236

GO:2001238

HMNXSV003018925

HMNXSV003028839

HMNXSV003049547

Hs2.11962.3.S1_3p_s_at

Hs2.171346.1.A1_3p_at

ILMN_1664235

ILMN_1717976

ILMN_1773925

ILMN_2279645

PH_hs_0001127

TC12002248.hg

g13540528_3p_s_at

Participates

as an output of

TP53 stimulates BCL2L14 gene expression (Homo sapiens)

Cross References

RefSeq

NP_620048.1, NP_620049.1, XP_011519151.1, XP_011519150.1, XP_016875452.1, XP_006719214.1, NP_110393.1

OpenTargets

ENSG00000121380

ENSEMBL

ENST00000631317, ENST00000627413, ENSP00000467086, ENST00000266434, ENST00000396367, ENST00000628315, ENST00000589718, ENSP00000487330, ENSP00000379653, ENSP00000486796, ENSP00000486050, ENSP00000266434, ENSP00000298566, ENSP00000485980, ENSP00000486560, ENST00000628783, ENST00000298566, ENST00000631251, ENSP00000309132, ENST00000308721

HPA

ENSG00000121380-BCL2L14

PRO

Q9BZR8

Pharos - Targets

Q9BZR8

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14680 MELK			0.645	4
UniProt:Q9Y296 TRAPPC4	2	TRAPPC4 [cytosol] (R-HSA-5683764) TRAPPC4 [plasma membrane] (R-HSA-2682314)	0.643	4
UniProt:Q8IUR0 TRAPPC5	1	TRAPPC5 [cytosol] (R-HSA-5683765)	0.643	4
UniProt:Q9Y5R8 TRAPPC1	3	TRAPPC1 [cytosol] (R-HSA-5683750) TRAPPC1 [extracellular region] (R-HSA-6806180) TRAPPC1 [azurophil granule lumen] (R-HSA-6799360)	0.643	4
UniProt:P48553 TRAPPC10	1	TRAPPC10 [cytosol] (R-HSA-5216159)	0.643	4
UniProt:O94776 MTA2	1	MTA2 [nucleoplasm] (R-HSA-4657009)	0.643	3
UniProt:O43617 TRAPPC3	1	TRAPPC3 [cytosol] (R-HSA-5683761)	0.643	4
UniProt:Q8WVR3 TPC14			0.643	4
UniProt:Q86SZ2 TRAPPC6B	1	TRAPPC6B [cytosol] (R-HSA-5685735)	0.643	4
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q96N21 AP4AT			0.556	3
UniProt:O14757 CHEK1	3	p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838) CHEK1 [nucleoplasm] (R-HSA-113826) CHEK1 [cytosol] (R-HSA-205285)	0.527	2
UniProt:trappc2_trappc2b_human EBI-20591397			0.527	3
UniProt:Q96Q05 TRAPPC9	1	TRAPPC9 [cytosol] (R-HSA-5683770)	0.527	3
UniProt:Q08380 LGALS3BP	2	LGALS3BP [extracellular region] (R-HSA-8848882) LGALS3BP [platelet dense granule lumen] (R-HSA-8848916)	0.499	2

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