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SEC11C [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-265065
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
Maturation of hRSV A proteins (Homo sapiens)
Nascent F signal peptide is cleaved at ER membrane (Homo sapiens)
(Signal Peptidase Complex) [endoplasmic reticulum membrane] (Homo sapiens)
SPC-C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Nascent G signal peptide is cleaved at ER membrane (Homo sapiens)
(Signal Peptidase Complex) [endoplasmic reticulum membrane] (Homo sapiens)
SPC-C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Nascent sG localizes to ER lumen, gets glycosylated (Homo sapiens)
(Signal Peptidase Complex) [endoplasmic reticulum membrane] (Homo sapiens)
SPC-C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Incretin synthesis, secretion, and inactivation (Homo sapiens)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Homo sapiens)
Signal peptidase hydrolyzes preproGLP-1 to proGLP-1 (Homo sapiens)
Signal Peptidase [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)
Signal peptidase hydrolyzes preproGIP to proGIP (Homo sapiens)
Signal Peptidase [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Synthesis, secretion, and deacylation of Ghrelin (Homo sapiens)
Cleavage of the signal peptide of Preproghrelin (Homo sapiens)
Signal Peptidase [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
Translation (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
Signal Peptidase [endoplasmic reticulum membrane] (Homo sapiens)
SEC11C [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BY50 SEC11C
Gene Names
SEC11C, SEC11L3, SPC21, SPCS4C
Chain
chain:1-192
Reference Genes
BioGPS Gene:90701 SEC11C
COSMIC (genes):SEC11C SEC11C
CTD Gene:90701 SEC11C
dbSNP Gene:90701 SEC11C
ENSEMBL:ENSG00000166562 SEC11C
HGNC:23400 SEC11C
KEGG:hsa:90701 SEC11C
Monarch:90701 SEC11C
NCBI Gene:90701 SEC11C
UCSC:Q9BY50 SEC11C
Reference Transcript
RefSeq:NM_033280.3 SEC11C
Other Identifiers
11744264_a_at
11760518_at
16852666
223299_PM_at
223299_at
235676_PM_at
235676_at
3790480
3790481
3790484
3790485
3790486
3790487
3790488
3790490
3790491
3790492
3790493
3790494
3790495
3790496
3790497
3790498
3790499
54079_at
54343_at
8021453
90701
A_23_P208009
GE62113
GO:0003824
GO:0004252
GO:0005515
GO:0005783
GO:0005787
GO:0005789
GO:0006465
GO:0006508
GO:0008233
GO:0016020
GO:0016787
GO:0043226
GO:0051604
GO:0140096
HMNXSV003020491
Hs.45107.0.A1_3p_at
ILMN_1701681
PH_hs_0022128
TC18000210.hg
g13182746_3p_at
Participates
as a component of
SPC-C [endoplasmic reticulum membrane] (Homo sapiens)
Signal Peptidase [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
SEC11C [endoplasmic reticulum membrane]
(Bos taurus)
SEC11C [endoplasmic reticulum membrane]
(Gallus gallus)
Ghost homologue of SEC11C [endoplasmic reticulum membrane]
(Canis familiaris)
Ghost homologue of SEC11C [endoplasmic reticulum membrane]
(Sus scrofa)
Sec11c [endoplasmic reticulum membrane]
(Mus musculus)
Sec11c [endoplasmic reticulum membrane]
(Rattus norvegicus)
sec11a [endoplasmic reticulum membrane]
(Danio rerio)
Cross References
RefSeq
NP_150596.1
ENSEMBL
ENSP00000468633
,
ENST00000587834
OpenTargets
ENSG00000166562
IntEnz
3.4.21.89
HPA
ENSG00000166562-SEC11C
PRO
Q9BY50
Pharos - Targets
Q9BY50
PDB
7P2Q
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IY26 PLPP6
1
PLPP6 [plasma membrane]
(R-HSA-8952144)
0.556
3
UniProt:P06681 C2
3
C2a [extracellular region]
(R-HSA-166780)
C2 [extracellular region]
(R-HSA-166778)
C2b [extracellular region]
(R-HSA-166781)
0.556
5
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.556
3
UniProt:Q9Y6X1 SERP1
2
SERP1 [endoplasmic reticulum membrane]
(R-HSA-381045)
SERP1 [cytosol]
(R-HSA-5250574)
0.556
3
UniProt:Q8N126 CADM3
1
CADM3 [plasma membrane]
(R-HSA-198169)
0.556
3
UniProt:P09601 HMOX1
4
HMOX1 [cytosol]
(R-HSA-9609901)
HMOX1 [endoplasmic reticulum membrane]
(R-HSA-189395)
HMOX1 [mitochondrial outer membrane]
(R-HSA-9708524)
HMOX1 [nucleoplasm]
(R-HSA-9708567)
0.556
3
UniProt:Q8WVV5 BTN2A2
1
BTN2A2 [plasma membrane]
(R-HSA-8851047)
0.556
3
UniProt:O00767 SCD
1
SCD [endoplasmic reticulum membrane]
(R-HSA-400117)
0.556
3
UniProt:Q5QGT7 RTP2
2
RTP2 [endoplasmic reticulum membrane]
(R-HSA-9752982)
RTP2 [plasma membrane]
(R-HSA-8939446)
0.556
3
UniProt:O95445 APOM
1
APOM [extracellular region]
(R-HSA-5216061)
0.527
2
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