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CADM3 [plasma membrane]
Stable Identifier
R-HSA-198169
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Necl-1, Cell adhesion molecule 3 precursor, CADM3_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Nectin/Necl trans heterodimerization (Homo sapiens)
Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1:Nectin 3 trans heterodimer interaction (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1:Nectin-3 trans heterodimer [cell junction] (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1:Nectin-1 trans heterodimer interaction (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1:Nectin-1 trans heterodimer [cell junction] (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Transhomodimerization of Nectin-like (Necl) proteins (Homo sapiens)
Necl-1/Necl-2/Necl-3 homodimer [plasma membrane] (Homo sapiens)
Necl-1 dimer [plasma membrane] (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
Necl-1/Necl-2/Necl-3 trans homodimer [cell junction] (Homo sapiens)
Necl-1/Necl-2/Necl-3 homodimer [plasma membrane] (Homo sapiens)
Necl-1 dimer [plasma membrane] (Homo sapiens)
CADM3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N126 CADM3
Gene Names
CADM3, IGSF4B, NECL1, SYNCAM3, TSLL1, UNQ225/PRO258
Chain
signal peptide:1-24, chain:25-398
Reference Genes
BioGPS Gene:57863 CADM3
COSMIC (genes):CADM3 CADM3
CTD Gene:57863 CADM3
dbSNP Gene:57863 CADM3
ENSEMBL:ENSG00000162706 CADM3
ENSEMBL_homo_sapiens_GENE:ENSG00000162706.13 CADM3
HGNC:17601 CADM3
KEGG Gene (Homo sapiens):57863 CADM3
Monarch:57863 CADM3
NCBI Gene:57863 CADM3
OMIM:609743 CADM3
UCSC:Q8N126 CADM3
Reference Transcript
RefSeq:NM_021189.4 CADM3
RefSeq:NM_001127173.2 CADM3
RefSeq:NM_001346510.1 CADM3
Other Identifiers
11723741_a_at
11723742_a_at
11723743_a_at
16672412
16672428
211677_PM_x_at
211677_x_at
213948_PM_x_at
213948_x_at
221921_PM_s_at
221921_s_at
226953_PM_at
226953_at
2362471
2362472
2362473
2362474
2362483
2362487
2362488
2362489
2362490
2362491
2362494
2362495
2362496
2362497
2362498
2362499
2362500
2362501
2362502
2362503
2362504
2362505
2362506
2362507
2362508
2362509
2362510
2362512
2362513
2362514
2362515
2362516
2362517
2362518
2362519
2362520
2362521
2362522
2362528
39288_at
46185_at
57863
7906417
7906435
87481_at
A_14_P129627
A_14_P132596
A_23_P115161
A_23_P201156
A_33_P3421923
GE56119
GE82601
GO:0005515
GO:0005886
GO:0005911
GO:0007155
GO:0007156
GO:0007157
GO:0016020
GO:0042803
GO:0070161
HMNXSV003002741
HMNXSV003013762
Hs.6164.0.S3_3p_at
Hs.6164.1.S1_3p_s_at
ILMN_1701827
PH_hs_0000025
PH_hs_0024045
PH_hs_0026955
TC01006336.hg
TC01006337.hg
g13631546_3p_s_at
Participates
as a component of
Necl-1 dimer [plasma membrane] (Homo sapiens)
Necl-1:Nectin-3 trans heterodimer [cell junction] (Homo sapiens)
Necl-1:Necl-2 trans heterodimer [cell junction] (Homo sapiens)
Necl-1:Nectin-1 trans heterodimer [cell junction] (Homo sapiens)
as an input of
Necl-1:Nectin 3 trans heterodimer interaction (Homo sapiens)
Necl-1:Necl-2 trans heterodimer interaction (Homo sapiens)
Necl-1:Nectin-1 trans heterodimer interaction (Homo sapiens)
Inferred To
cadm3 [plasma membrane]
(Xenopus tropicalis)
Cadm3 [plasma membrane]
(Mus musculus)
Cadm3 [plasma membrane]
(Rattus norvegicus)
CADM3 [plasma membrane]
(Bos taurus)
CADM3 [plasma membrane]
(Canis familiaris)
CADM3 [plasma membrane]
(Gallus gallus)
CADM3 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001120645.1
,
NP_067012.1
,
NP_001333439.1
OpenTargets
ENSG00000162706
GeneCards
Q8N126
HPA
ENSG00000162706-CADM3
Ensembl
ENST00000368125
,
ENST00000368124
,
ENSP00000357107
,
ENSG00000162706
,
ENSP00000357106
PRO
Q8N126
Pharos - Targets
Q8N126
HMDB Protein
HMDBP07527
PDB
1Z9M
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BY50 SEC11C
1
SEC11C [endoplasmic reticulum membrane]
(R-HSA-265065)
0.556
3
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