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3x4Hyp-3Hyp-5Hyl-COL4A6(?-1691) [extracellular region]
Stable Identifier
R-HSA-2468233
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
3,4-Hyp 5-Hyl collagen alpha-6(IV) chain C-term fragment
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type IV degradation by MMP2,3,4,9,10,12 (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL4A6(?-1691) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL4A6(?-1691) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP19 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL4A6(?-1691) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14031 COL4A6
Gene Names
COL4A6
Chain
signal peptide:1-22, chain:23-1691
Reference Genes
BioGPS Gene:1288 COL4A6
COSMIC (genes):COL4A6 COL4A6
CTD Gene:1288 COL4A6
dbSNP Gene:1288 COL4A6
ENSEMBL:ENSG00000197565 COL4A6
ENSEMBL_homo_sapiens_GENE:ENSG00000197565.17 COL4A6
HGNC:2208 COL4A6
KEGG Gene (Homo sapiens):1288 COL4A6
Monarch:1288 COL4A6
NCBI Gene:1288 COL4A6
OMIM:303631 COL4A6
UCSC:Q14031 COL4A6
Reference Transcript
RefSeq:NM_033641.3 COL4A6
RefSeq:NM_001847.3 COL4A6
RefSeq:NM_001287760.1 COL4A6
Other Identifiers
11725910_a_at
11741797_a_at
11750015_a_at
11751887_a_at
11751888_x_at
11751893_a_at
1288
17113195
211473_PM_s_at
211473_s_at
213992_PM_at
213992_at
39939_at
4017539
4017540
4017541
4017542
4017543
4017544
4017545
4017547
4017548
4017549
4017550
4017551
4017552
4017553
4017556
4017557
4017558
4017560
4017561
4017563
4017564
4017565
4017567
4017568
4017569
4017570
4017571
4017577
4017578
4017579
4017580
4017581
4017582
4017583
4017584
4017586
4017589
4017592
4017593
4017594
4017595
4017596
4017597
4017598
4017599
4017601
4017603
4017605
4017607
4017608
4017609
4017611
4017613
4017614
4017615
4017617
4017620
4017625
4017626
4017632
4017633
4017634
4017661
4017677
4017678
4017679
779_at
8174389
A_23_P217379
D21337_at
GE83658
GE88012
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0023052
GO:0030020
GO:0030198
GO:0030312
GO:0031012
GO:0038063
GO:0043226
GO:0062023
GO:0071230
HMNXSV003029591
HMNXSV003040585
Hs.408.2.S1_3p_at
ILMN_1675857
ILMN_1811289
ILMN_1813021
PH_hs_0000049
TC0X001267.hg
g496977_3p_a_at
Participates
as a member of
Cleaved collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
GalHyl-COL4A6 [endoplasmic reticulum lumen]
COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen]
5Hyl-COL4A6 [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
3,4-Hyp 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
GlcGalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-COL4A6(?-1691) [extracellular region]
3x4Hyp-GalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-5Hyl-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A6(23-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6(23-?) [extracellular region]
COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6(?-1691) [extracellular region]
5Hyl-COL4A6(23-?) [extracellular region]
GalHyl-COL4A6(?-1691) [extracellular region]
5Hyl-COL4A6(?-1691) [extracellular region]
GlcGalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-GalHyl-COL4A6(23-?) [extracellular region]
GalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6(?-1691) [extracellular region]
COL4A6(23-?) [extracellular region]
3x4Hyp-5Hyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-COL4A6(23-?) [extracellular region]
3x4Hyp-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-COL4A6 [extracellular region]
5Hyl-COL4A6 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [extracellular region]
3x4Hyp-COL4A6 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A6 [extracellular region]
3x4Hyp-GalHyl-COL4A6 [extracellular region]
GalHyl-COL4A6 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6 [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6 [extracellular region]
3x4Hyp-5Hyl-COL4A6 [extracellular region]
COL4A6 [extracellular region]
GlcGalHyl-COL4A6 [extracellular region]
Inferred To
COL4A6 [extracellular region]
(Bos taurus)
COL4A6 [extracellular region]
(Canis familiaris)
COL4A6 [extracellular region]
(Sus scrofa)
Col4a6 [extracellular region]
(Mus musculus)
Col4a6 [extracellular region]
(Rattus norvegicus)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
(2S,5R)-5-hydroxylysine at unknown position
PsiMod Name
(2S,5R)-5-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to 5-hydroxy-L-lysine.
Cross References
RefSeq
NP_001838.2
,
NP_001274689.1
,
NP_378667.1
OpenTargets
ENSG00000197565
HPA
ENSG00000197565-COL4A6
GeneCards
Q14031
Ensembl
ENSG00000197565
,
ENSP00000361290
,
ENST00000334504
,
ENSP00000334733
,
ENST00000372216
PRO
Q14031
Pharos - Targets
Q14031
Orphanet
15775
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
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