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PDS5A [chromosome]
Stable Identifier
R-HSA-2466360
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
chromosome
Synonyms
Sister chromatid cohesion protein PDS5 homolog A, PDS5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prometaphase (Homo sapiens)
Resolution of Sister Chromatid Cohesion (Homo sapiens)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Homo sapiens)
Sister Chromosomal Arms:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome] (Homo sapiens)
Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
Sister Chromosomal Arms:Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Homo sapiens)
Sister Chromosomal Arms:Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
Sister Chromosomal Arms:p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
Resolution of sister chromatids (Homo sapiens)
Sister Chromosomal Arms:p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
S Phase (Homo sapiens)
Establishment of Sister Chromatid Cohesion (Homo sapiens)
CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Homo sapiens)
Sister Chromosomal Arms:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome] (Homo sapiens)
Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome] (Homo sapiens)
PDS5 [chromosome] (Homo sapiens)
PDS5A [chromosome] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q29RF7 PDS5A
Gene Names
PDS5A, KIAA0648, PDS5, PIG54
Chain
chain:1-1337
Reference Genes
BioGPS Gene:23244 PDS5A
COSMIC (genes):PDS5A PDS5A
CTD Gene:23244 PDS5A
dbSNP Gene:23244 PDS5A
ENSEMBL:ENSG00000121892 PDS5A
HGNC:29088 PDS5A
KEGG:hsa:23244 PDS5A
Monarch:23244 PDS5A
NCBI Gene:23244 PDS5A
OMIM:613200 PDS5A
UCSC:Q29RF7 PDS5A
Reference Transcript
RefSeq:NM_001100399.2 PDS5A
RefSeq:XM_054349456.1 PDS5A
RefSeq:XM_011513672.3 PDS5A
RefSeq:XM_017007928.1 PDS5A
RefSeq:XM_047449931.1 PDS5A
RefSeq:XM_054349457.1 PDS5A
RefSeq:NM_001100400.2 PDS5A
Participates
as a member of
PDS5 [chromosome] (Homo sapiens)
Other forms of this molecule
PDS5A [nucleoplasm]
PDS5A [chromosome, centromeric region]
PDS5A [cytosol]
Inferred To
PDS5 [chromosome]
(Saccharomyces cerevisiae)
evl-14 [chromosome]
(Caenorhabditis elegans)
pds5a [chromosome]
(Danio rerio)
PDS5A [chromosome]
(Bos taurus)
PDS5A [chromosome]
(Canis familiaris)
PDS5A [chromosome]
(Gallus gallus)
PDS5A [chromosome]
(Sus scrofa)
Pds5a [chromosome]
(Mus musculus)
Pds5a [chromosome]
(Rattus norvegicus)
pds5 [chromosome]
(Dictyostelium discoideum)
pds5 [chromosome]
(Drosophila melanogaster)
pds5 [chromosome]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001093869.1
,
XP_011511974.1
,
XP_054205431.1
,
XP_054205432.1
,
XP_047305887.1
,
NP_001093870.1
,
XP_016863417.1
OpenTargets
ENSG00000121892
ENSEMBL
ENSG00000121892
,
ENST00000503396
,
ENSP00000303427
,
ENST00000303538
,
ENSP00000426749
HPA
ENSG00000121892-PDS5A
GeneCards
PDS5A
PRO
Q29RF7
Pharos - Targets
Q29RF7
GlyGen
Q29RF7
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O60216 RAD21
14
RAD21 [nucleoplasm]
(R-HSA-163042)
RAD21 [chromosome, centromeric region]
(R-HSA-2466012)
RAD21 [chromosome]
(R-HSA-1638775)
p-S454-RAD21 [chromosome, centromeric region]
(R-HSA-2485163)
RAD21(1-172) [chromosome, centromeric region]
(R-HSA-2467793)
p-S454-RAD21(451-631) [chromosome, centromeric region]
(R-HSA-2467790)
RAD21(173-450) [chromosome, centromeric region]
(R-HSA-2500296)
RAD21(1-172) [cytosol]
(R-HSA-2484901)
RAD21(173-450) [cytosol]
(R-HSA-2500308)
p-S454-RAD21(451-631) [cytosol]
(R-HSA-2500309)
RAD21 [cytosol]
(R-HSA-2484795)
p-S454-RAD21 [chromosome]
(R-HSA-2485164)
p-S454-RAD21 [cytosol]
(R-HSA-2500310)
monoSUMO1-K-RAD21 [nucleoplasm]
(R-HSA-3108183)
0.857
6
UniProt:Q7Z5K2 WAPL
4
WAPAL [cytosol]
(R-HSA-2484802)
WAPAL [chromosome]
(R-HSA-2577090)
WAPAL [chromosome, centromeric region]
(R-HSA-2577088)
WAPAL [nucleoplasm]
(R-HSA-2466355)
0.813
9
UniProt:Q96FF9 CDCA5
6
p-S21,S75,T159-CDCA5 [chromosome]
(R-HSA-2468266)
p-S21,S75,T159-CDCA5 [cytosol]
(R-HSA-2484804)
p-S21,S75,T159-CDCA5 [chromosome, centromeric region]
(R-HSA-2468269)
CDCA5 [chromosome]
(R-HSA-2468149)
CDCA5 [chromosome, centromeric region]
(R-HSA-2468260)
CDCA5 [nucleoplasm]
(R-HSA-2466357)
0.642
4
UniProt:Q61550 Rad21
15
Rad21 [nucleoplasm]
(R-MMU-3108183)
Double-strand-break repair protein rad21 homolog [nucleoplasm]
(R-MMU-912350)
phospho-Rad21 [cytosol]
(R-MMU-2500310)
phospho-Rad21 [chromosome]
(R-MMU-2485164)
Rad21 [cytosol]
(R-MMU-2484795)
phospho-Rad21 [cytosol]
(R-MMU-2500309)
Rad21 [cytosol]
(R-MMU-2500308)
Rad21 [cytosol]
(R-MMU-2484901)
Rad21 [chromosome, centromeric region]
(R-MMU-2500296)
phospho-Rad21 [chromosome, centromeric region]
(R-MMU-2467790)
Rad21 [chromosome, centromeric region]
(R-MMU-2467793)
phospho-Rad21 [chromosome, centromeric region]
(R-MMU-2485163)
Rad21 [chromosome]
(R-MMU-1638775)
Rad21 [chromosome, centromeric region]
(R-MMU-2466012)
Rad21 [nucleoplasm]
(R-MMU-163042)
0.564
2
UniProt:P04201 MAS1
1
MAS1 [plasma membrane]
(R-HSA-9944591)
0.527
2
UniProt:P35414 APLNR
1
APLNR [plasma membrane]
(R-HSA-374259)
0.527
3
UniProt:Q9Y639 NPTN
1
NPTN [plasma membrane]
(R-HSA-8856422)
0.527
3
UniProt:O75695 RP2
1
RP2 [cilium]
(R-HSA-5624052)
0.527
2
UniProt:Q13304 GPR17
1
GPR17 [plasma membrane]
(R-HSA-416429)
0.527
2
UniProt:P46059 SLC15A1
1
SLC15A1 [plasma membrane]
(R-HSA-428022)
0.527
2
UniProt:Q5FBB7 SGO1
3
SGOL1 [cytosol]
(R-HSA-376227)
SGO1 [nucleoplasm]
(R-HSA-2468161)
p-S-SGO1 [nucleoplasm]
(R-HSA-9929718)
0.462
4
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.462
2
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