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SLC15A1 [plasma membrane]
Stable Identifier
R-HSA-428022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
PEPT1, Solute carrier family 15 member 1, S15A1_HUMAN, Peptide transporter 1
Icon
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Proton/oligopeptide cotransporters (Homo sapiens)
SLC25A1 transports di-/tri-peptides and peptide-like drugs (Homo sapiens)
SLC15A1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46059 SLC15A1
Gene Names
SLC15A1, PEPT1
Chain
chain:1-708
Reference Genes
BioGPS Gene:6564 SLC15A1
COSMIC (genes):SLC15A1 SLC15A1
CTD Gene:6564 SLC15A1
dbSNP Gene:6564 SLC15A1
ENSEMBL:ENSG00000088386 SLC15A1
ENSEMBL_homo_sapiens_GENE:ENSG00000088386.17 SLC15A1
HGNC:10920 SLC15A1
KEGG Gene (Homo sapiens):6564 SLC15A1
Monarch:6564 SLC15A1
NCBI Gene:6564 SLC15A1
OMIM:600544 SLC15A1
UCSC:P46059 SLC15A1
Reference Transcript
RefSeq:NM_005073.3 SLC15A1
Other Identifiers
11735143_at
11752275_a_at
16780481
207254_PM_at
207254_at
32906_at
3522339
3522340
3522341
3522342
3522344
3522347
3522348
3522349
3522354
3522355
3522357
3522359
3522361
3522362
3522363
3522364
3522365
3522367
3522368
3522374
3522375
3522376
3522377
3522378
3522386
6564
7972461
A_23_P128609
A_33_P3373273
GE59010
GO:0005215
GO:0005427
GO:0005886
GO:0005903
GO:0006811
GO:0006857
GO:0015031
GO:0015293
GO:0015333
GO:0015833
GO:0016020
GO:0016324
GO:0022857
GO:0035673
GO:0042937
GO:0055085
GO:0071916
GO:0140206
GO:0140207
GO:1902600
HMNXSV003030467
PH_hs_0026493
TC13000824.hg
U21936_at
g4827007_3p_at
Inferred To
Homologues of SLC15A1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC15A1 [plasma membrane]
(Dictyostelium discoideum)
Homologues of SLC15A1 [plasma membrane]
(Drosophila melanogaster)
PEPT1 [plasma membrane]
(Gallus gallus)
pept-3 [plasma membrane]
(Caenorhabditis elegans)
CG32780 [plasma membrane]
(Drosophila melanogaster)
SLC15A1 [plasma membrane]
(Bos taurus)
SLC15A1 [plasma membrane]
(Canis familiaris)
SLC15A1 [plasma membrane]
(Dictyostelium discoideum)
SLC15A1 [plasma membrane]
(Sus scrofa)
Slc15a1 [plasma membrane]
(Mus musculus)
Slc15a1 [plasma membrane]
(Rattus norvegicus)
yin [plasma membrane]
(Drosophila melanogaster)
Dmel\CG9444 [plasma membrane]
(Drosophila melanogaster)
pept-1 [plasma membrane]
(Caenorhabditis elegans)
slc15a1b [plasma membrane]
(Danio rerio)
pept-2 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_005064.1
ZINC - World Drugs
S15A1_HUMAN
Guide to Pharmacology - Targets
984
OpenTargets
ENSG00000088386
ZINC - Substances
S15A1_HUMAN
ZINC target
P46059
ZINC - Biogenic
S15A1_HUMAN
PRO
P46059
PDB
7PMX
,
7PN1
,
7PMW
ZINC - Metabolites
S15A1_HUMAN
HPA
ENSG00000088386-SLC15A1
GeneCards
P46059
Ensembl
ENSP00000365686
,
ENSG00000088386
,
ENST00000376503
Pharos - Targets
P46059
ZINC - Predictions - Purchasable
S15A1_HUMAN
HMDB Protein
HMDBP02749
Interactors (26)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q29RF7 PDS5A
4
PDS5A [cytosol]
(R-HSA-2484799)
PDS5A [chromosome]
(R-HSA-2466360)
PDS5A [chromosome, centromeric region]
(R-HSA-2468259)
PDS5A [nucleoplasm]
(R-HSA-2468043)
0.527
2
UniProt:P0C0L4 C4A
11
p-C4A [endoplasmic reticulum lumen]
(R-HSA-8956932)
C4A [endoplasmic reticulum lumen]
(R-HSA-8956717)
C4A alpha4 fragment [extracellular region]
(R-HSA-981506)
C4A alpha3 [extracellular region]
(R-HSA-981503)
C4A(956-1336) [plasma membrane]
(R-HSA-981501)
C4A-derived C4a [extracellular region]
(R-HSA-166737)
C4 alpha [extracellular region]
(R-HSA-166729)
S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region]
(R-HSA-166736)
C4A(20-675) [extracellular region]
(R-HSA-166734)
C4A(1454-1744) [extracellular region]
(R-HSA-166731)
dNQ-C4A(757-1446) [extracellular region]
(R-HSA-2855053)
0.527
2
UniProt:P68366 TUBA4A
9
TUBA4A [cytosol]
(R-HSA-191694)
TUBA4A [axonemal microtubule]
(R-HSA-5610443)
TUBA4A [extracellular region]
(R-HSA-350734)
Polyglutamyl-TUBA4A [cytosol]
(R-HSA-8867386)
L-isoglutamyl polyglycyl-TUBA4A [cytosol]
(R-HSA-8867378)
TUBA4A unfolded [cytosol]
(R-HSA-392771)
TUBA4A folding intermediate [cytosol]
(R-HSA-392800)
Ac K40 TUBA4A [axonemal microtubule]
(R-HSA-5624859)
AcK-TUBA4A [cytosol]
(R-HSA-5618318)
0.527
2
UniProt:P24468 NR2F2
1
NR2F2 [nucleoplasm]
(R-HSA-1183002)
0.527
2
UniProt:Q96BW9 TAM41
0.527
2
UniProt:Q96A46 SLC25A28
1
SLC25A28 [mitochondrial inner membrane]
(R-HSA-1362394)
0.527
2
UniProt:A6NJ78 MET15
0.527
2
UniProt:Q14849 STARD3
1
STARD3 [cytosol]
(R-HSA-5216089)
0.527
2
UniProt:Q96DA6 DNAJC19
1
DNAJC19 [mitochondrial inner membrane]
(R-HSA-1252127)
0.527
2
UniProt:Q02338 BDH1
1
BDH1 [mitochondrial matrix]
(R-HSA-73922)
0.527
2
UniProt:Q96DA2 RAB39B
3
GGC-RAB39B [Golgi membrane]
(R-HSA-8877796)
GGC-RAB39B [cytosol]
(R-HSA-8874006)
RAB39B [cytosol]
(R-HSA-8873679)
0.527
2
UniProt:P33897 ABCD1
8
ABCD1 R617C [peroxisomal membrane]
(R-HSA-5685069)
ABCD1 T77_L82del [peroxisomal membrane]
(R-HSA-5685088)
ABCD1 S606L [peroxisomal membrane]
(R-HSA-5685104)
ABCD1 [peroxisomal membrane]
(R-HSA-382566)
ABCD1 [cytosol]
(R-HSA-382587)
ABCD1 G277R [peroxisomal membrane]
(R-HSA-5685058)
ABCD1 M1V [peroxisomal membrane]
(R-HSA-5685059)
ABCD1 R554H [peroxisomal membrane]
(R-HSA-5685072)
0.527
2
UniProt:P84085 ARF5
1
ARF5 [cytosol]
(R-HSA-6807737)
0.527
2
UniProt:P23458 JAK1
6
p-Y1034,Y1035-JAK1 [cytosol]
(R-HSA-9005335)
JAK1 [endosome]
(R-HSA-8983168)
p-JAK1 [cytosol]
(R-HSA-8950711)
p-Y1034-JAK1 [cytosol]
(R-HSA-1112543)
JAK1 [cytosol]
(R-HSA-451898)
p-Y-JAK1 [cytosol]
(R-HSA-451921)
0.527
2
UniProt:P20337 RAB3B
2
GGC-RAB3B [cytosol]
(R-HSA-8874009)
RAB3B [cytosol]
(R-HSA-8873715)
0.527
2
UniProt:B0YJ81 HACD1
1
PTPLA [endoplasmic reticulum membrane]
(R-HSA-5676076)
0.527
2
UniProt:Q96E52 OMA1
3
OMA1(144-447) [mitochondrial inner membrane]
(R-HSA-9840539)
OMA1(144-524) [mitochondrial inner membrane]
(R-HSA-9840540)
OMA1 [mitochondrial inner membrane]
(R-HSA-8867510)
0.527
2
UniProt:Q9BWM7 SFXN3
0.527
2
UniProt:Q6UXV4 APOOL
3
APOOL (MIC27) [mitochondrial inner membrane]
(R-HSA-8949612)
APOOL [extracellular region]
(R-HSA-8862979)
APOOL [platelet alpha granule lumen]
(R-HSA-8863003)
0.527
2
UniProt:Q9NR77 PXMP2
2
PXMP2 [cytosol]
(R-HSA-9603794)
PXMP2 [peroxisomal membrane]
(R-HSA-8953432)
0.527
2
UniProt:Q8NE86 MCU
1
MCU [mitochondrial inner membrane]
(R-HSA-8949184)
0.527
2
UniProt:Q8TD22 SFXN5
0.527
2
UniProt:A6ZKI3 RTL8C
0.527
2
UniProt:O14981 BTAF1
0.527
2
UniProt:Q86Y56 DAAF5
0.527
2
UniProt:P50748 KNTC1
1
KNTC1 [cytosol]
(R-HSA-376233)
0.527
2
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