Formation of selenosugars for excretion

Stable Identifier
R-HSA-2408499
Type
Pathway
Species
Homo sapiens
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Formation of selenosugars for excretion
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Selenite (SeO3(2-)), potentially formed from oxidised H2Se, combines with glutathione (GSH) and 1beta-methylseleno-N-acetyl-D-galactosamine derivative to form selonosugars which are further metabolised and then excreted.

Literature References
PubMed ID Title Journal Year
12441402 Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range

Kobayashi, Y, Ogra, Y, Ishiwata, K, Takayama, H, Aimi, N, Suzuki, KT

Proc. Natl. Acad. Sci. U.S.A. 2002
16842833 Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Suzuki, KT, Somekawa, L, Suzuki, N

Toxicol. Appl. Pharmacol. 2006
Participants
Events
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Event Information
Go Biological Process
selenium compound metabolic process (0001887)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)