Formation of selenosugars for excretion

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R-HSA-2408499
Type
Pathway
Species
Homo sapiens
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Selenite (SeO3(2-)), potentially formed from oxidised H2Se, combines with glutathione (GSH) and 1beta-methylseleno-N-acetyl-D-galactosamine derivative to form selonosugars which are further metabolised and then excreted.

Literature References
PubMed ID Title Journal Year
16842833 Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Suzuki, KT, Suzuki, N, Somekawa, L

Toxicol. Appl. Pharmacol. 2006
12441402 Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range

Kobayashi, Y, Suzuki, KT, Ogra, Y, Takayama, H, Aimi, N, Ishiwata, K

Proc. Natl. Acad. Sci. U.S.A. 2002
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