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3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region]
Stable Identifier
R-HSA-2268719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
4-Hyp 5-Gal-Hyl collagen alpha-2(I) propeptide
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Removal of fibrillar collagen N-propeptides (Homo sapiens)
Fibrillar procollagens [extracellular region] (Homo sapiens)
Procollagen type I [extracellular region] (Homo sapiens)
Alpha-2(I) propeptides [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens [extracellular region] (Homo sapiens)
Fibrillar procollagens [extracellular region] (Homo sapiens)
Procollagen type I [extracellular region] (Homo sapiens)
Alpha-2(I) propeptides [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08123 COL1A2
Gene Names
COL1A2
Chain
signal peptide:1-22, propeptide:23-79, chain:80-1119, propeptide:1120-1366
Reference Genes
BioGPS Gene:1278 COL1A2
COSMIC (genes):COL1A2 COL1A2
CTD Gene:1278 COL1A2
dbSNP Gene:1278 COL1A2
ENSEMBL:ENSG00000164692 COL1A2
ENSEMBL_homo_sapiens_GENE:ENSG00000164692.19 COL1A2
HGNC:2198 COL1A2
KEGG Gene (Homo sapiens):1278 COL1A2
Monarch:1278 COL1A2
NCBI Gene:1278 COL1A2
OMIM:120160 COL1A2
UCSC:P08123 COL1A2
Reference Transcript
RefSeq:NM_000089.3 COL1A2
Other Identifiers
11715353_s_at
11715354_a_at
11715355_at
11715356_x_at
11753294_a_at
11753295_x_at
1278
17048473
202403_PM_s_at
202403_s_at
202404_PM_s_at
202404_s_at
3013077
3013078
3013079
3013083
3013084
3013086
3013091
3013092
3013093
3013094
3013095
3013096
3013098
3013101
3013102
3013103
3013104
3013105
3013106
3013107
3013108
3013109
3013110
3013111
3013113
3013114
3013115
3013116
3013117
3013118
3013119
3013120
3013124
3013125
3013127
3013128
3013129
3013130
3013132
3013135
3013137
3013139
3013141
3013142
3013143
3013144
3013146
3013148
3013151
3013153
3013155
3013156
3013157
3013158
3013160
3013161
3013162
3013163
32305_at
32306_g_at
32307_s_at
49162_f_at
60071_s_at
63596_f_at
64347_s_at
75214_f_at
8134263
A_24_P265274
A_24_P277934
GE80889
GO:0001501
GO:0001568
GO:0002020
GO:0003013
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005584
GO:0005615
GO:0005783
GO:0005788
GO:0007179
GO:0007266
GO:0008217
GO:0023052
GO:0030020
GO:0030198
GO:0030199
GO:0030282
GO:0030312
GO:0030674
GO:0031012
GO:0032963
GO:0042476
GO:0042802
GO:0043226
GO:0043589
GO:0046332
GO:0046872
GO:0048407
GO:0048856
GO:0060090
GO:0062023
GO:0065003
GO:0070062
GO:0070208
GO:0071230
GO:0085029
HMNXSV003019525
Hs.179573.0.A1_3p_a_at
ILMN_1785272
ILMN_2104356
TC07000559.hg
TC07002463.hg
Z74616_s_at
g4502946_3p_a_at
Participates
as a member of
Alpha-2(I) propeptides [extracellular region] (Homo sapiens)
Other forms of this molecule
GlcGalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
GalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
5Hyl-COL1A2(25-1366) [endoplasmic reticulum lumen]
Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp Glu-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp Glu-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl Collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl Glu-Gal-Hyl-collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-hydroxyprolyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Lysino-5-ketonorlysyl 5-hydroxylysl-collagen alpha-1(I) chain [extracellular region]
Lysino-5-ketonorlysyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Lysino-5-ketonorlysyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
3x4Hyp-Alys-COL1A2 [extracellular region]
3x4Hyp-Alys-GlcGalHyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-Alys-GalHyl-COL1A2 [extracellular region]
Alys-GlcGalHyl-COL1A2 [extracellular region]
3x4Hyp-Alys-GalHyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-5Hyl-Alys-COL1A2 [extracellular region]
3x4Hyp-3Hyp-Alys-GlcGalHyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-Alys-COL1A2 [extracellular region]
3x4Hyp-5Hyl-Alys-COL1A2 [extracellular region]
Alys-COL1A2 [extracellular region]
5Hyl-Alys-COL1A2 [extracellular region]
Alys-GalHyl-COL1A2 [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp Glu-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp Glu-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-hydroxyprolyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl Glu-Gal-Hyl-collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp 5-Gal-Hyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl Collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-hydroxyprolyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Hydroxyallysyl 4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
Hydroxyallysyl 5-hydroxylysyl collagen alpha-2(I) chain [extracellular region]
Hydroxyallysyl 3,4-Hyp 5-Hyl collagen alpha-2(I) chain [extracellular region]
3x4Hyp-3Hyp-COL1A2(25-1366) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A2(25-1366) [extracellular region]
GlcGalHyl-COL1A2(25-1366) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A2(25-1366) [extracellular region]
3x4Hyp-COL1A2(25-1366) [extracellular region]
3x4Hyp-5Hyl-COL1A2(25-1366) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A2(25-1366) [extracellular region]
5Hyl-COL1A2(25-1366) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2(25-1366) [extracellular region]
GalHyl-COL1A2(25-1366) [extracellular region]
COL1A2(25-1366) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A2(80-1366) [extracellular region]
3x4Hyp-GalHyl-COL1A2(80-1366) [extracellular region]
3x4Hyp-COL1A2(80-1366) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A2(80-1366) [extracellular region]
GlcGalHyl-COL1A2(80-1366) [extracellular region]
GalHyl-COL1A2(80-1366) [extracellular region]
3x4Hyp-5Hyl-COL1A2(80-1366) [extracellular region]
3x4Hyp-3Hyp-COL1A2(80-1366) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A2(80-1366) [extracellular region]
5Hyl-COL1A2(80-1366) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2(80-1366) [extracellular region]
COL1A2(80-1366) [extracellular region]
3x4Hyp-GalHyl-COL1A2(80-953) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A2(954-1102) [extracellular region]
3x4Hyp-3Hyp-COL1A2(954-1102) [extracellular region]
3x4Hyp-5Hyl-COL1A2(1-954) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2(954-1102) [extracellular region]
3x4Hyp-5Hyl-COL1A2(80-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A2(80-953) [extracellular region]
3x4Hyp-GalHyl-COL1A2(954-1102) [extracellular region]
3x4Hyp-COL1A2(954-1102) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A2(80-953) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2(80-953) [extracellular region]
5Hyl-COL1A2(954-1102) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A2(954-1102) [extracellular region]
GalHyl-COL1A2(954-1102) [extracellular region]
COL1A2(80-954) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A2(954-1102) [extracellular region]
GalHyl-COL1A2(80-953) [extracellular region]
GlcGalHyl-COL1A2(954-1102) [extracellular region]
COL1A2(954-1102) [extracellular region]
3x4Hyp-COL1A2(80-953) [extracellular region]
GlcGalHyl-COL1A2(80-953) [extracellular region]
3x4Hyp-3Hyp-COL1A2(80-953) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A2(80-953) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A2 [extracellular region]
5Hyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-COL1A2 [extracellular region]
3x4Hyp-5Hyl-COL1A2 [extracellular region]
GalHyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A2 [extracellular region]
COL1A2 [extracellular region]
3x4Hyp-GalHyl-COL1A2 [extracellular region]
3x4Hyp-COL1A2 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A2 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A2 [extracellular region]
GlcGalHyl-COL1A2 [extracellular region]
COL1A2(25-1366) [endoplasmic reticulum lumen]
5Hyl-COL1A2(80-953) [extracellular region]
Inferred To
3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region]
(Bos taurus)
3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region]
(Mus musculus)
3x4Hyp-GalHyl-COL1A2(25-1366) [extracellular region]
(Rattus norvegicus)
col1a2 [extracellular region]
(Danio rerio)
col1a2 [extracellular region]
(Xenopus tropicalis)
COL1A2 [extracellular region]
(Canis familiaris)
COL1A2 [extracellular region]
(Gallus gallus)
COL1A2 [extracellular region]
(Sus scrofa)
cle-1 [extracellular region]
(Caenorhabditis elegans)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_000080.2
OpenTargets
ENSG00000164692
GeneCards
P08123
HPA
ENSG00000164692-COL1A2
Ensembl
ENSP00000297268
,
ENST00000297268
,
ENSG00000164692
PRO
P08123
Pharos - Targets
P08123
Orphanet
15768
PDB
5CTI
,
5CVA
,
6JEC
,
5CTD
HMDB Protein
HMDBP01758
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43765 SGTA
1
SGTA [cytosol]
(R-HSA-5423595)
0.805
11
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.718
6
UniProt:Q9UMX0-2 UBQLN1
0.718
6
UniProt:Q6PIL6 KCNIP4
1
KCNIP4 [plasma membrane]
(R-HSA-5577152)
0.718
9
UniProt:P02452 COL1A1
20
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023648)
3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023667)
GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023604)
GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022999)
3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023559)
3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023582)
COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1650777)
3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1985659)
3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022446)
3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022951)
3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022954)
5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1985663)
Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396137)
Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396440)
Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396471)
Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396464)
Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396068)
Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396388)
Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396315)
Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396441)
0.576
5
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
5
UniProt:Q96GM5 SMARCD1
1
SMARCD1 [nucleoplasm]
(R-HSA-389255)
0.556
3
UniProt:O00303 EIF3F
1
EIF3F [cytosol]
(R-HSA-72540)
0.556
3
UniProt:Q96EQ0 SGTB
0.556
3
UniProt:Q14696 MESD
0.556
3
UniProt:Q7Z624 CAMKMT
1
CAMKMT [cytosol]
(R-HSA-6786199)
0.527
2
UniProt:O43615 TIMM44
1
TIMM44(?-452) [mitochondrial inner membrane]
(R-HSA-1252038)
0.527
2
UniProt:O75616 ERAL1
1
ERAL1 [mitochondrial matrix]
(R-HSA-8932742)
0.527
2
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