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HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane]
Stable Identifier
R-HSA-2130595
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
HA23_HUMAN, HLA-DQA1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Internalization of MHC II:Ii clathrin coated vesicle (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA II alpha chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Uncoating of clathrin-coated vesicles and fusion with endosomes (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA II alpha chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01909 HLA-DQA1
Gene Names
HLA-DQA1
Chain
signal peptide:1-23, chain:24-254
Reference Genes
BioGPS Gene:3117 HLA-DQA1
COSMIC (genes):HLA-DQA1 HLA-DQA1
CTD Gene:3117 HLA-DQA1
dbSNP Gene:3117 HLA-DQA1
ENSEMBL:ENSG00000196735 HLA-DQA1
ENSEMBL_homo_sapiens_GENE:ENSG00000196735.13 HLA-DQA1
ENSEMBL_homo_sapiens_GENE:ENSG00000206305.12 HLA-DQA1
ENSEMBL_homo_sapiens_GENE:ENSG00000232062.9 HLA-DQA1
HGNC:4942 HLA-DQA1
KEGG Gene (Homo sapiens):3117 HLA-DQA1
Monarch:3117 HLA-DQA1
NCBI Gene:3117 HLA-DQA1
OMIM:146880 HLA-DQA1
UCSC:P01909 HLA-DQA1
Reference Transcript
RefSeq:NM_002122.3 HLA-DQA1
Other Identifiers
11724799_x_at
11750528_x_at
11753898_x_at
11756083_x_at
11758340_x_at
17028326
17038609
17041240
203290_PM_at
203290_at
212671_PM_s_at
212671_s_at
213831_PM_at
213831_at
2903223
2903224
2903227
2903229
2903231
2903233
2903234
2903235
2903236
2903259
2903265
2903266
3117
32773_at
8118556
8178199
8179489
A_23_P30900
A_24_P196827
A_24_P326084
A_24_P393230
A_33_P3293049
GE81121
GE890404
GO:0000139
GO:0002250
GO:0002376
GO:0002503
GO:0002504
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0007155
GO:0010008
GO:0012507
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032395
GO:0032588
GO:0042605
GO:0042613
GO:0043226
GO:0050778
GO:0050870
GO:0060089
GO:0065003
GO:0098553
HMNXSV003000947
HMNXSV003054155
HMNXSV003055601
HMNXSV003056103
Hs.198253.1.A1_3p_a_at
Hs.198253.2.A1_3p_s_at
ILMN_1808405
K01160_s_at
M26041_s_at
M34996_s_at
PH_hs_0033085
TC6_cox_hap2000091.hg
TC6_qbl_hap6000082.hg
TC6_ssto_hap7000077.hg
g4504406_3p_at
p26545
p26546
Participates
as a member of
HLA II alpha chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DQ [lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DQ [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DQ [Golgi membrane]
HLA class II histocompatibility antigen, DQ [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DQ [transport vesicle membrane]
HLA class II histocompatibility antigen, DQ [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DQ [lysosomal membrane]
HLA class II histocompatibility antigen, DQ [plasma membrane]
Inferred To
hla-dpa1 [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
mhc2dgb [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
BOLA-DQA1 [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
Homologues of HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
RT1-Ba [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
mhc2-daa [clathrin-coated endocytic vesicle membrane]
(Xenopus tropicalis)
mhc2daa [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
si:busm1-194e12.8 [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
mhc2d8.45b1 [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
H2-Aa [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
HLA class II histocompatibility antigen, DQ [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
DLA-DQA1 [clathrin-coated endocytic vesicle membrane]
(Canis familiaris)
SLA-DQA1 [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
Cross References
RefSeq
NP_002113.2
OpenTargets
ENSG00000196735
GeneCards
P01909
HPA
ENSG00000196735-HLA-DQA1
Ensembl
ENSP00000413237
,
ENST00000399678
,
ENST00000374949
,
ENST00000399675
,
ENSG00000206305
,
ENSP00000382586
,
ENST00000343139
,
ENST00000418023
,
ENSP00000339398
,
ENSP00000364087
,
ENSP00000378767
,
ENST00000444296
,
ENSG00000232062
,
ENSP00000387892
,
ENSP00000372738
,
ENST00000383251
,
ENST00000395363
,
ENSG00000196735
,
ENSP00000382583
PRO
P01909
Pharos - Targets
P01909
Orphanet
16829
PDB
8W83
,
4OZI
,
5KSA
,
5KSB
,
4GG6
,
5KSU
,
8W86
,
8W84
,
1UVQ
,
1JK8
,
8W85
,
1S9V
,
6MFG
,
7SG0
,
6U3M
,
7SG1
,
5KSV
,
6MFF
,
6XP6
,
2NNA
,
4OZH
,
4OZF
,
6U3N
,
7SG2
,
4OZG
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04233 CD74
13
CD74(81-104) [lysosomal lumen]
(R-HSA-2213220)
CD74(81-104) [lysosomal membrane]
(R-HSA-2130446)
CD74(1-117) [lysosomal membrane]
(R-HSA-2130632)
CD74 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-1181241)
CD74 [ER to Golgi transport vesicle membrane]
(R-HSA-2130456)
CD74 [Golgi membrane]
(R-HSA-2214388)
CD74 [trans-Golgi network membrane]
(R-HSA-2130493)
CD74 [transport vesicle membrane]
(R-HSA-2130624)
CD74 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130522)
CD74 [endocytic vesicle membrane]
(R-HSA-2130460)
CD74(1-176) [lysosomal membrane]
(R-HSA-2130602)
CD74 [lysosomal membrane]
(R-HSA-2130320)
CD74 [plasma membrane]
(R-HSA-2130666)
0.674
4
UniProt:O43612 HCRT
2
HCRT(70-97) [extracellular region]
(R-HSA-389473)
HCRT(34-66) [extracellular region]
(R-HSA-389500)
0.564
2
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