Serotonin and melatonin biosynthesis

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R-HSA-209931
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Homo sapiens
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Serotonin (5-HT) is a hormone and neurotransmitter used for regulatory purposes in animal CNS. In the human brain, serotonin is involved in many physiological functions such as sleep, pain, mood and is the precursor to melatonin, a hormone produced in the pineal gland.

Literature References
PubMed ID Title Journal Year
18155917 Melatonin in the skin: synthesis, metabolism and functions

Wortsman, J, Slominski, A, Zmijewski, MA, Paus, R, Tobin, DJ

Trends Endocrinol Metab 2008
16942634 Tryptophan metabolism in the central nervous system: medical implications

Rook, GA, Lowry, CA, Lightman, SL, Evans, AK, Nutt, DJ, Ruddick, JP

Expert Rev Mol Med 2006
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