N-acetylation of serotonin

Stable Identifier
R-HSA-209792
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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N-acetylation of serotonin
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Serotonin N-acetyltransferase (AANAT) catalyzes the N-acetylation of serotonin to form N-acetylserotonin. AANAT utilizes acetyl-CoA as the donor of the acetyl group.

Literature References
PubMed ID Title Journal Year
8661026 The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression.

Bernard, M, Klein, DC, Roseboom, PH, Coon, SL, Rodriguez, IR, Mazuruk, K

Genomics 1996
Participants
Input
Output
Participates
as an event of
Catalyst Activity

aralkylamine N-acetyltransferase activity of AANAT [cytosol]

Physical Entity
AANAT [cytosol] (Homo sapiens)
Activity
aralkylamine N-acetyltransferase activity (GO:0004059)
Orthologous Events
N-acetylation of serotonin (Bos taurus)
N-acetylation of serotonin (Canis familiaris)
N-acetylation of serotonin (Danio rerio)
N-acetylation of serotonin (Gallus gallus)
N-acetylation of serotonin (Mus musculus)
N-acetylation of serotonin (Rattus norvegicus)
N-acetylation of serotonin (Saccharomyces cerevisiae)
N-acetylation of serotonin (Schizosaccharomyces pombe)
N-acetylation of serotonin (Sus scrofa)
N-acetylation of serotonin (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-01-08)
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