HS(3)-HSPG2 [plasma membrane]

Stable Identifier
R-HSA-2076627
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
HSPG2, Perlecan
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P98160 HSPG2
Gene Names
HSPG2
Chain
signal peptide:1-21, chain:22-4391, chain:3687-4391, chain:4197-4391
Reference Genes
BioGPS Gene:3339 HSPG2
COSMIC (genes):HSPG2 HSPG2
CTD Gene:3339 HSPG2
dbSNP Gene:3339 HSPG2
ENSEMBL:ENSG00000142798 HSPG2
ENSEMBL_homo_sapiens_GENE:ENSG00000142798 HSPG2
HGNC:5273 HSPG2
KEGG Gene (Homo sapiens):3339 HSPG2
Monarch:3339 HSPG2
NCBI Gene:3339 HSPG2
OMIM:142461 HSPG2
UCSC:P98160 HSPG2
Reference Transcript
Other Identifiers
0000070292
11753471_a_at
11757600_x_at
16683105
18892
201654_s_at
201655_3p_s_at
201655_s_at
20718
2400795
2400796
2400797
2400798
2400799
2400800
2400801
2400802
2400803
2400804
2400805
2400808
2400810
2400812
2400813
2400815
2400816
2400818
2400819
2400820
2400822
2400824
2400825
2400826
2400827
2400829
2400832
2400833
2400835
2400836
2400838
2400840
2400841
2400842
2400844
2400845
2400846
2400847
2400848
2400849
2400850
2400851
2400853
2400854
2400855
2400856
2400857
2400858
2400859
2400860
2400862
2400863
2400865
2400866
2400867
2400869
2400870
2400871
2400873
2400874
2400875
2400877
2400878
2400879
2400880
2400881
2400882
2400883
2400884
2400885
2400886
2400887
2400888
2400889
2400890
2400891
2400892
2400893
2400894
2400895
2400896
2400897
2400898
2400904
2400905
2400907
2400908
2400909
2400910
2400912
2400914
2400915
2400917
2400918
2400919
2400920
2400921
2400923
2400924
2400925
2400926
2400927
2400928
2400930
2400931
2400933
2400934
2400936
2400937
2400938
2400939
2400940
2400942
2400946
2400947
2400948
2400950
2400951
2400959
2400960
2400961
32845_at
3339
3SH4
3SH5
7913450
9820
A0A2R8YH07
A_33_P3321657
A_33_P3380612
A_33_P3380618
A_33_P3380625
AAA52699
AAA52700
AAB21121
AL445795
AL590103
AL590556
CAA44373
CAB009820
CAB020718
CAC18534
CCDS30625
ENSG00000142798
ENSP00000363827
ENST00000374695
EntrezGene:3339
g184426_3p_a_at
GE81524
GO:0001523
GO:0001525
GO:0003674
GO:0005198
GO:0005509
GO:0005515
GO:0005575
GO:0005576
GO:0005604
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0005886
GO:0005925
GO:0006024
GO:0006027
GO:0006629
GO:0006810
GO:0006898
GO:0006950
GO:0006954
GO:0007420
GO:0008022
GO:0008150
GO:0009056
GO:0009058
GO:0016192
GO:0016525
GO:0030021
GO:0030154
GO:0030198
GO:0031012
GO:0032991
GO:0043167
GO:0043202
GO:0043226
GO:0044267
GO:0046872
GO:0048646
GO:0048856
GO:0050750
GO:0062023
GO:0070062
GO:0072358
GO:0098797
HGNC:5273
HPA018892
Hs.211573.0.S1_3p_a_at
HSPG2
HSPG2-203
IPR000034
IPR000082
IPR000742
IPR001791
IPR001881
IPR002049
IPR002172
IPR003598
IPR003599
IPR007110
IPR013032
IPR013098
IPR013106
IPR013320
IPR013783
IPR023415
IPR036055
IPR036179
L22078
M64283
M85289
M85289_at
MIM:142461
MIM:224410
MIM:255800
NM_001291860
NM_005529
NP_001278789
NP_005520
PF00008
PF00052
PF00053
PF00054
PF00057
PF07679
PF13895
PF13927
PR00261
S76436
SM00179
SM00180
SM00181
SM00192
SM00200
SM00281
SM00282
SM00406
SM00408
SM00409
TC01002328.hg
uc001bfj.4
UPI0000212778
X62515
X62515_s_at
XM_011541318
XM_017001120
XM_017001121
XM_017001122
XP_011539620
XP_016856609
XP_016856610
XP_016856611
Participant Of
hasMember
Other forms of this molecule
HSPG2(22-4196) [extracellular region]
HSPG2(4197-4391) [extracellular region]
HSPG2(22-?) [extracellular region]
HSPG2(?-4391) [extracellular region]
HSPG2(22-4391) [extracellular region]
HSPG2(22-4391) [plasma membrane]
Heparan-HSPG2 [Golgi lumen]
Heparan(1)-HSPG2 [Golgi lumen]
Heparan(2)-HSPG2 [Golgi lumen]
Heparan(3)-HSPG2 [Golgi lumen]
Heparan(4)-HSPG2 [Golgi lumen]
HS(5)-HSPG2 [plasma membrane]
HS(1)-HSPG2 [plasma membrane]
HS(2)-HSPG2 [plasma membrane]
HS(4)-HSPG2 [plasma membrane]
HS(1)-HSPG2 [Golgi lumen]
HS(6)-HSPG2 [Golgi lumen]
HSPG2(3687-4391) [extracellular region]
Gal-Gal-Xyl-HSPG2 [Golgi lumen]
GlcA-Gal-Gal-Xyl-HSPG2 [Golgi lumen]
Gal-Xyl-HSPG2 [Golgi lumen]
XylS-HSPG2(22-4391) [Golgi lumen]
HSPG2(22-4391) [Golgi lumen]
HS(6)-HSPG2 [lysosomal lumen]
HSPG2(22-4391) [lysosomal lumen]
HS(6)-HSPG2 [plasma membrane]
HS(5)-HSPG2 [Golgi lumen]
HS(4)-HSPG2 [Golgi lumen]
HS(2)-HSPG2 [Golgi lumen]
HS(3)-HSPG2 [Golgi lumen]
Inferred To
HS(3)-HSPG2 [plasma membrane] (Bos taurus)
HS(3)-HSPG2 [plasma membrane] (Canis familiaris)
HS(3)-HSPG2 [plasma membrane] (Danio rerio)
HS(3)-HSPG2 [plasma membrane] (Drosophila melanogaster)
HS(3)-HSPG2 [plasma membrane] (Gallus gallus)
HS(3)-HSPG2 [plasma membrane] (Mus musculus)
HS(3)-HSPG2 [plasma membrane] (Rattus norvegicus)
HS(3)-HSPG2 [plasma membrane] (Sus scrofa)
HS(3)-HSPG2 [plasma membrane] (Xenopus tropicalis)
Homologues of HS(3)-HSPG2 [plasma membrane] (Canis familiaris)
Homologues of HS(3)-HSPG2 [plasma membrane] (Danio rerio)
Homologues of HS(3)-HSPG2 [plasma membrane] (Drosophila melanogaster)
Homologues of HS(3)-HSPG2 [plasma membrane] (Gallus gallus)
Homologues of HS(3)-HSPG2 [plasma membrane] (Mus musculus)
Homologues of HS(3)-HSPG2 [plasma membrane] (Sus scrofa)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63654) at unknown position
Modification
beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
OpenTargets
GeneCards
DOCK Blaster
PRO
Orphanet
HMDB Protein
PDB
Interactors (2)