WWTR1 (TAZ), TBX5, and PCAF form a complex

Stable Identifier
R-HSA-2032794
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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WWTR1 (TAZ), TBX5, and PCAF form a complex
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In the nucleus the WWTR1 (TAZ) transcriptional coactivator can bind the TBX5 transcription factor and PCAF (KAT2B) histone acetyltransferase to form a complex. The stoichiometry of this complex is unknown (Murakami et al. 2005).
Literature References
PubMed ID Title Journal Year
16332960 A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome

Murakami, M, Olson, EN, Nakagawa, O, Nakagawa, M

Proc Natl Acad Sci U S A 2005
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Orthologous Events
WWTR1 (TAZ), TBX5, and PCAF form a complex (Bos taurus)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Caenorhabditis elegans)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Canis familiaris)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Danio rerio)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Gallus gallus)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Mus musculus)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Rattus norvegicus)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Sus scrofa)
WWTR1 (TAZ), TBX5, and PCAF form a complex (Xenopus tropicalis)
Authored
D'Eustachio, P  (2012-02-03)
Reviewed
Sudol, M  (2012-02-03)
Created
D'Eustachio, P  (2012-01-08)
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