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NFKB1(1-433):RELA [nucleoplasm]
Stable Identifier
R-HSA-194047
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
NF-kB complex
GO Cellular Component
transcription regulator complex
(0005667)
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Activated CEBPB and NFKB complex bind IL8 promoter (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL8 Gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Regulation of IL6 transcription (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Stimulation of IL8 transcription in senescent cells (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL8 Gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
Regulation of NFE2L2 gene expression (Homo sapiens)
NFkB binds the NFE2L2 gene (Homo sapiens)
NFE2L2 gene:NFkB complex [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
NFkB dependent NFE2L2 expression (Homo sapiens)
NFE2L2 gene:NFkB complex [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Developmental Biology (Homo sapiens)
Adipogenesis (Homo sapiens)
Transcriptional regulation of white adipocyte differentiation (Homo sapiens)
Expression of PPARG (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by VENTX (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Regulation of IL6 transcription (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)
Activation of NF-kappaB in B cells (Homo sapiens)
NF-kappaB translocates from the cytosol to the nucleus (Homo sapiens)
NF-kappaB p50,p65,c-Rel dimer [nucleoplasm] (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CD209 (DC-SIGN) signaling (Homo sapiens)
Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
CLEC7A/inflammasome pathway (Homo sapiens)
IL1B gene is transcribed (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated NF-kB activation (Homo sapiens)
NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
p75NTR signals via NF-kB (Homo sapiens)
NF-kB is activated and signals survival (Homo sapiens)
NF-kB migrates to the nucleus and turns on transcription (Homo sapiens)
NFKB1(1-433):RELA [nucleoplasm] (Homo sapiens)
Participants
components
NFKB1(1-433) [nucleoplasm]
(Homo sapiens)
RELA [nucleoplasm]
(Homo sapiens)
Participates
as an input of
NFkB binds the NFE2L2 gene (Homo sapiens)
Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
Activated CEBPB and NFKB complex bind IL8 promoter (Homo sapiens)
as a component of
NFE2L2 gene:NFkB complex [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL8 Gene [nucleoplasm] (Homo sapiens)
as an output of
NF-kB migrates to the nucleus and turns on transcription (Homo sapiens)
NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)
as a member of
NF-kappaB p50,p65,c-Rel dimer [nucleoplasm] (Homo sapiens)
This entity regulates
Negatively
Expression of PPARG
(Homo sapiens)
Positively
IL1B gene is transcribed
(Homo sapiens)
Inferred To
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm]
(Drosophila melanogaster)
NFKB1(1-433):RELA [nucleoplasm]
(Bos taurus)
NFKB1(1-433):RELA [nucleoplasm]
(Canis familiaris)
NFKB1(1-433):RELA [nucleoplasm]
(Gallus gallus)
NFKB1(1-433):RELA [nucleoplasm]
(Mus musculus)
NFKB1(1-433):RELA [nucleoplasm]
(Sus scrofa)
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