Reactome | TUBB4A [cytosol]

TUBB4A [cytosol]

Stable Identifier

R-HSA-190588

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

beta tubulin 5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P04350 TUBB4A

Gene Names

TUBB4A, TUBB4, TUBB5

Chain

chain:1-444

Reference Genes

BioGPS Gene:10382 TUBB4A

COSMIC (genes):TUBB4A TUBB4A

CTD Gene:10382 TUBB4A

dbSNP Gene:10382 TUBB4A

ENSEMBL:ENSG00000104833 TUBB4A

HGNC:20774 TUBB4A

KEGG:hsa:10382 TUBB4A

Monarch:10382 TUBB4A

NCBI Gene:10382 TUBB4A

OMIM:602662 TUBB4A

UCSC:P04350 TUBB4A

Reference Transcript

Other Identifiers

10382

11744256_a_at

11744257_s_at

11748829_a_at

11749715_s_at

11751118_x_at

16867756

212664_PM_at

212664_at

213476_3p_x_at

213476_PM_x_at

213476_x_at

33678_i_at

3847960

3847961

3847962

3847963

3847964

3847965

3847966

3847967

3847968

3847969

3847971

3847972

3847973

3847974

3847975

3847976

38699_at

4050505

429_f_at

8033233

A_23_P113656

A_23_P50338

GE81597

GO:0000226

GO:0000278

GO:0003824

GO:0003924

GO:0005198

GO:0005200

GO:0005509

GO:0005515

GO:0005525

GO:0005634

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0005874

GO:0005929

GO:0005930

GO:0007010

GO:0007017

GO:0015630

GO:0016787

GO:0031115

GO:0033269

GO:0042995

GO:0043025

GO:0043209

GO:0043226

GO:0045171

GO:0046872

GO:0070062

GO:0072686

HMNXSV003056538

Hs.110837.0.S2_3p_at

ILMN_1682459

PH_hs_0006099

TC19001099.hg

X00734_at

Participates

as a component of

as a member of

beta tubulin [cytosol] (Homo sapiens)

as a candidate of

beta-tubulin [cytosol] (Homo sapiens)

Other forms of this molecule

TUBB4A folding intermediate [cytosol]

TUBB4A unfolded [cytosol]

Polyglycyl-TUBB4A [cytosol]

Polyglutamyl-TUBB4A [cytosol]

TUBB4A [axonemal microtubule]

Inferred To

ben-1 [cytosol] (Caenorhabditis elegans)

wu:fd02b12 [cytosol] (Danio rerio)

tubb4b [cytosol] (Danio rerio)

TUBB4A [cytosol] (Bos taurus)

TUBB4A [cytosol] (Caenorhabditis elegans)

TUBB4A [cytosol] (Canis familiaris)

TUBB4A [cytosol] (Dictyostelium discoideum)

TUBB4A [cytosol] (Drosophila melanogaster)

TUBB4A [cytosol] (Gallus gallus)

TUBB4A [cytosol] (Plasmodium falciparum)

TUBB4A [cytosol] (Rattus norvegicus)

TUBB4A [cytosol] (Sus scrofa)

tbb-1 [cytosol] (Caenorhabditis elegans)

tbb-6 [cytosol] (Caenorhabditis elegans)

wu:fj33a08 [cytosol] (Danio rerio)

Tubulin beta-4A chain [cytosol] (Mus musculus)

Homologues of TUBB4A [cytosol] (Caenorhabditis elegans)

Homologues of TUBB4A [cytosol] (Danio rerio)

Homologues of TUBB4A [cytosol] (Drosophila melanogaster)

tubb4a [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001276056.1, NP_006078.2, NP_001276052.1, NP_001276060.1, NP_001276059.1, NP_001276058.1

ENSEMBL

ENST00000264071, ENSP00000264071

OpenTargets

ENSG00000104833

HPA

ENSG00000104833-TUBB4A

PRO

P04350

Pharos - Targets

P04350

GlyGen

P04350

Orphanet

TUBB4A

HMDB Protein

HMDBP08047

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.67	6
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.569	10
UniProt:Q07954 LRP1	2	LRP1 [endocytic vesicle membrane] (R-HSA-2230981) LRP1 [plasma membrane] (R-HSA-1454844)	0.527	2
UniProt:P36404 ARL2	2	ARL2 [mitochondrial matrix] (R-HSA-5250216) ARL2 [cytosol] (R-HSA-5216230)	0.527	3
UniProt:P07437 TUBB	3	TUBB [extracellular region] (R-HSA-380317) TUBB [azurophil granule lumen] (R-HSA-6799370) TUBB [cytosol] (R-HSA-9020816)	0.527	2
UniProt:P54764 EPHA4	2	p-Y596,Y602-EPHA4 [plasma membrane] (R-HSA-3928352) EPHA4 [plasma membrane] (R-HSA-2682325)	0.527	2
UniProt:P22736 NR4A1	2	p-S351-NR4A1 [nucleoplasm] (R-HSA-199846) NR4A1 [nucleoplasm] (R-HSA-199831)	0.524	2

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