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Go!
centrosome [cytosol]
Stable Identifier
R-HSA-380268
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prometaphase (Homo sapiens)
Recruitment of NuMA to mitotic centrosomes (Homo sapiens)
Association of NuMA with microtubules (Homo sapiens)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Homo sapiens)
Mature centrosome:nucleated microtubules [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Translocation of NuMA to the centrosomes (Homo sapiens)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
AURKA Activation by TPX2 (Homo sapiens)
TPX2 binds AURKA at centrosomes (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
TPX2 promotes AURKA autophosphorylation (Homo sapiens)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome maturation (Homo sapiens)
Loss of proteins required for interphase microtubule organization from the centrosome (Homo sapiens)
Loss of C-Nap-1 from centrosomes (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Loss of Nlp from mitotic centrosomes (Homo sapiens)
Plk1-mediated phosphorylation of Nlp (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Recruitment of mitotic centrosome proteins and complexes (Homo sapiens)
Recruitment of CDK11p58 to the centrosomes (Homo sapiens)
Centrosomes containing recruited CDK11p58 [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Recruitment of Plk1 to centrosomes (Homo sapiens)
Centrosome associated Plk1 [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)
AJUBA binds centrosome-associated AURKA (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:AURKA:AJUBA [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
AJUBA facilitates AURKA autophosphorylation (Homo sapiens)
Centrosome:AURKA:AJUBA [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
AURKA phosphorylates PLK1 (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
BORA binds PLK1 and AURKA (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
Participants
components
ACTR1A [cytosol]
(Homo sapiens)
AKAP9 [cytosol]
(Homo sapiens)
ALMS1 [cytosol]
(Homo sapiens)
AZI1 [cytosol]
(Homo sapiens)
CCP110 [cytosol]
(Homo sapiens)
CDK1 [cytosol]
(Homo sapiens)
CDK5RAP2 [cytosol]
(Homo sapiens)
CENPJ [cytosol]
(Homo sapiens)
CEP135 [cytosol]
(Homo sapiens)
CEP152 [cytosol]
(Homo sapiens)
CEP164 [cytosol]
(Homo sapiens)
CEP192 [cytosol]
(Homo sapiens)
CEP250 [cytosol]
(Homo sapiens)
CEP290 [cytosol]
(Homo sapiens)
CEP41 [cytosol]
(Homo sapiens)
CEP57 [cytosol]
(Homo sapiens)
CEP63 [cytosol]
(Homo sapiens)
CEP70 [cytosol]
(Homo sapiens)
CEP72 [cytosol]
(Homo sapiens)
CEP76 [cytosol]
(Homo sapiens)
CEP78 [cytosol]
(Homo sapiens)
CETN2 [cytosol]
(Homo sapiens)
CKAP5 [cytosol]
(Homo sapiens)
CLASP1 [cytosol]
(Homo sapiens)
CNTRL [cytosol]
(Homo sapiens)
CSNK1D [cytosol]
(Homo sapiens)
CSNK1E [cytosol]
(Homo sapiens)
DCTN1-2 [cytosol]
(Homo sapiens)
DCTN2 [cytosol]
(Homo sapiens)
DCTN3 [cytosol]
(Homo sapiens)
DYNC1H1 [cytosol]
(Homo sapiens)
DYNC1I2 [cytosol]
(Homo sapiens)
DYNLL1 [cytosol]
(Homo sapiens)
FGFR1OP [cytosol]
(Homo sapiens)
HAUS complex [cytosol]
(Homo sapiens)
HSP90AA1 [cytosol]
(Homo sapiens)
MAPRE1 [cytosol]
(Homo sapiens)
NDE1 [cytosol]
(Homo sapiens)
NEDD1 [cytosol]
(Homo sapiens)
NEK2 [cytosol]
(Homo sapiens)
NINL [cytosol]
(Homo sapiens)
ODF2 [cytosol]
(Homo sapiens)
OFD1 [cytosol]
(Homo sapiens)
PAFAH1B1 [cytosol]
(Homo sapiens)
PCM1 [cytosol]
(Homo sapiens)
PCNT [cytosol]
(Homo sapiens)
PLK1 [cytosol]
(Homo sapiens)
PLK4 [cytosol]
(Homo sapiens)
PPP2R1A [cytosol]
(Homo sapiens)
PRKACA [cytosol]
(Homo sapiens)
PRKAR2B [cytosol]
(Homo sapiens)
SDCCAG8 [cytosol]
(Homo sapiens)
SFI1 [cytosol]
(Homo sapiens)
SSNA1 [cytosol]
(Homo sapiens)
TUBA1A [cytosol]
(Homo sapiens)
TUBA4A [cytosol]
(Homo sapiens)
TUBB [extracellular region]
(Homo sapiens)
TUBB4A [cytosol]
(Homo sapiens)
TUBB4B [cytosol]
(Homo sapiens)
TUBG1 [cytosol]
(Homo sapiens)
YWHAE [cytosol]
(Homo sapiens)
YWHAG [cytosol]
(Homo sapiens)
Participates
as a component of
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
Centrosome associated Plk1 [cytosol] (Homo sapiens)
Centrosomes containing recruited CDK11p58 [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
as an input of
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Homo sapiens)
Recruitment of Plk1 to centrosomes (Homo sapiens)
Recruitment of CDK11p58 to the centrosomes (Homo sapiens)
Plk1-mediated phosphorylation of Nlp (Homo sapiens)
Loss of C-Nap-1 from centrosomes (Homo sapiens)
Inferred To
centrosome [cytosol]
(Bos taurus)
centrosome [cytosol]
(Canis familiaris)
centrosome [cytosol]
(Gallus gallus)
centrosome [cytosol]
(Mus musculus)
centrosome [cytosol]
(Rattus norvegicus)
centrosome [cytosol]
(Sus scrofa)
centrosome [cytosol]
(Xenopus tropicalis)
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