Reactome | NFKBIB [cytosol]

NFKBIB [cytosol]

Stable Identifier

R-HSA-168132

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

IkBB, NF-kappaB inhibitor beta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15653 NFKBIB

Gene Names

NFKBIB, IKBB, TRIP9

Chain

chain:1-356

Reference Genes

BioGPS Gene:4793 NFKBIB

COSMIC (genes):NFKBIB NFKBIB

CTD Gene:4793 NFKBIB

dbSNP Gene:4793 NFKBIB

ENSEMBL:ENSG00000104825 NFKBIB

ENSEMBL_homo_sapiens_GENE:ENSG00000104825.17 NFKBIB

ENSEMBL_homo_sapiens_GENE:ENSG00000282905.2 NFKBIB

HGNC:7798 NFKBIB

KEGG Gene (Homo sapiens):4793 NFKBIB

Monarch:4793 NFKBIB

NCBI Gene:4793 NFKBIB

OMIM:604495 NFKBIB

UCSC:Q15653 NFKBIB

Reference Transcript

Other Identifiers

11725835_at

11725836_x_at

11745604_x_at

11745832_a_at

16861895

214062_3p_x_at

214062_PM_x_at

214062_x_at

214448_3p_x_at

214448_PM_x_at

214448_x_at

228388_3p_at

228388_PM_at

228388_at

3832763

3832764

3832765

3832767

3832768

3832769

3832770

3832771

3832772

3832773

3832774

41065_at

43069_at

4793

8028552

A_23_P330895

A_23_P79086

A_24_P161086

A_33_P3343545

GE81164

GE87209

GO:0003713

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006954

GO:0007165

GO:0023052

GO:0043122

GO:0043226

GO:0045893

GO:0071222

GO:0140110

HMNXSV003016327

HMNXSV003028472

HMNXSV003035878

Hs.9731.0.S1_3p_a_at

Hs.9731.0.S1_3p_at

Hs.9731.0.S1_3p_x_at

Hs.9731.1.S1_3p_a_at

Hs.9731.1.S1_3p_x_at

ILMN_1674152

ILMN_1712754

L40407_at

PH_hs_0030976

TC19000534.hg

TC19002129.hg

p34312

Participates

as a member of

Other forms of this molecule

p-S19,S23-Ub-NFKBIB [cytosol]

p-S19,S23-NFKBIB [cytosol]

Inferred To

si:dkeyp-110c7.1 [cytosol] (Danio rerio)

NFKBIB [cytosol] (Bos taurus)

NFKBIB [cytosol] (Canis familiaris)

NFKBIB [cytosol] (Gallus gallus)

NFKBIB [cytosol] (Sus scrofa)

Nfkbib [cytosol] (Mus musculus)

Nfkbib [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_002494.2, NP_001230045.1

OpenTargets

ENSG00000104825

GeneCards

Q15653

HPA

ENSG00000104825-NFKBIB

Ensembl

ENSG00000282905, ENSG00000104825, ENST00000634647, ENST00000313582, ENSP00000489138, ENST00000635517, ENSP00000459728, ENST00000572515, ENSP00000312988, ENSP00000489145

PRO

Q15653

Pharos - Targets

Q15653

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04206 RELA	6	MeK310-RELA [nucleoplasm] (R-HSA-8865233) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) p-S276-RELA [nucleoplasm] (R-HSA-5624468) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) RELA [cytosol] (R-HSA-168172) RELA [nucleoplasm] (R-HSA-177676)	0.75	6
UniProt:P19838 NFKB1	8	NFKB1(1-968) [specific granule lumen] (R-HSA-6799557) NFKB1(1-968) [extracellular region] (R-HSA-6806304) NFKB1(1-968) [secretory granule lumen] (R-HSA-6801004) NFKB1(1-433) [cytosol] (R-HSA-168168) NFKB1(1-433) [nucleoplasm] (R-HSA-177655) NFKB1(1-968) [cytosol] (R-HSA-451607) p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451611) 3xUb-p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451619)	0.604	3

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