Reactome | GUSB [lysosomal lumen]

GUSB [lysosomal lumen]

Stable Identifier

R-HSA-1678846

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Beta-glucuronidase, BGLR_HUMAN

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External Reference Information

External Reference

UniProt:P08236 GUSB

Gene Names

GUSB

Chain

signal peptide:1-22, chain:23-651

Reference Genes

BioGPS Gene:2990 GUSB

COSMIC (genes):GUSB GUSB

CTD Gene:2990 GUSB

dbSNP Gene:2990 GUSB

ENSEMBL:ENSG00000169919 GUSB

ENSEMBL:ENSG00000169919.17 GUSB

HGNC:4696 GUSB

KEGG Gene (Homo sapiens):2990 GUSB

Monarch:2990 GUSB

NCBI Gene:2990 GUSB

OMIM:611499 GUSB

UCSC:P08236 GUSB

Reference Transcript

Other Identifiers

11719271_s_at

17058176

202605_PM_at

202605_at

2868809

2946613

2990

3004396

3053693

3053694

3053695

3053696

3053697

3053698

3053699

3053700

3053706

3053707

3053709

3053711

3053713

3053715

3053717

3053722

3053723

3053724

3053725

3053729

33308_at

8139859

A_23_P334608

GE61184

GO:0003824

GO:0004553

GO:0004566

GO:0005102

GO:0005576

GO:0005615

GO:0005764

GO:0005773

GO:0005975

GO:0006027

GO:0006790

GO:0008152

GO:0016020

GO:0016787

GO:0016798

GO:0019391

GO:0019904

GO:0030163

GO:0030200

GO:0030207

GO:0030214

GO:0030246

GO:0031410

GO:0035578

GO:0043202

GO:0043226

GO:0043231

GO:0070062

GO:1901135

GO:1904813

HMNXSV003041271

ILMN_1669878

M15182_at

PH_hs_0023271

PH_hs_0032345

TC07001457.hg

g4504222_3p_at

Participates

as a component of

GUSB tetramer [lysosomal lumen] (Homo sapiens)

Other forms of this molecule

GUSB R611W [lysosomal lumen]

GUSB R216W [lysosomal lumen]

GUSB A354V [lysosomal lumen]

GUSB R356* [lysosomal lumen]

GUSB [ficolin-1-rich granule lumen]

GUSB [extracellular region]

GUSB [azurophil granule lumen]

GUSB S52F [lysosomal lumen]

Inferred To

gusb [lysosomal lumen] (Xenopus tropicalis)

GUSB [lysosomal lumen] (Bos taurus)

GUSB [lysosomal lumen] (Caenorhabditis elegans)

GUSB [lysosomal lumen] (Canis familiaris)

GUSB [lysosomal lumen] (Danio rerio)

GUSB [lysosomal lumen] (Gallus gallus)

GUSB [lysosomal lumen] (Sus scrofa)

Dmel\CG15117 [lysosomal lumen] (Drosophila melanogaster)

Gusb [lysosomal lumen] (Mus musculus)

Gusb [lysosomal lumen] (Rattus norvegicus)

Cross References

RefSeq

NP_001280033.1, NP_000172.2, NP_001280034.1, XP_005250354.1, NP_001271219.1

OpenTargets

ENSG00000169919

ZINC - Substances

BGLR_HUMAN

ZINC - Biogenic

BGLR_HUMAN

ZINC target

P08236

PRO

P08236

PDB

3HN3, 1BHG

GeneCards

P08236

HPA

ENSG00000169919-GUSB

Ensembl

ENSP00000302728, ENST00000421103, ENSG00000169919, ENST00000304895, ENSP00000391390

Pharos - Targets

P08236

ZINC - Predictions - Purchasable

BGLR_HUMAN

Orphanet

16179

HMDB Protein

HMDBP00839

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.547	2

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